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Noxafil 40mg Syrup
Prescription Required
Salt Composition : Posaconazole
Manufacturer : MSD PHARMACEUTICALS PVT LTD
Origin of Medicine : United States of America
1 Bottle(s) Of 105ml
Introduction to Noxafil 40mg Syrup
Noxafil 40mg Syrup belongs to a class of drugs called azole antifungals containing the active ingredient Posaconazole. It is used to treat and prevent certain fungal infections. The medication is commonly prescribed for preventing and treating invasive fungal infections in patients with weak immune systems, such as those undergoing cancer chemotherapy, stem cell transplantation, or those with HIV/AIDS. It also treats certain fungal infections in individuals who cannot tolerate or have not responded to other antifungal treatments.
This drug is contraindicated in individuals with known hypersensitivity or allergy to other antifungal medications like ketoconazole, fluconazole, itraconazole, or voriconazole. Before taking Noxafil 40mg Syrup, it is necessary to consult with your physician if you have certain heart conditions like abnormal heart rhythm (long QTc interval), weakness of the heart muscle, heart failure, or any heart rhythm disturbances, or if you experience severe kidney problems, diarrhea or vomiting while on treatment with this drug, it's important to inform your physician immediately, as these conditions may affect the medicine's effectiveness.
Noxafil 40mg Syrup may affect the levels of potassium, magnesium, or calcium in the blood. If you have any problems with these electrolyte levels, your doctor will monitor you closely during treatment. If you are taking medications such as vincristine, vinblastine, or any other vinca alkaloids drugs which are used to treat cancer, you should also inform your physician before initiating the treatment. If you are pregnant, use this drug only if your doctor advises. Consuming this drug while breastfeeding may be unsafe because it passes into breast milk and affects the child. Do not breastfeed while taking this medicine.
Uses of Noxafil 40mg Syrup
- Treatment of fungal infections
Therapeutic Effects of Noxafil 40mg Syrup
Noxafil 40mg Syrup works by inhibiting the synthesis of ergosterol, a vital component of the fungal cell membrane. This disruption weakens the membrane, leading to cell death, and effectively treats fungal infections.
Interaction of Noxafil 40mg Syrup with other drugs
Inform your physician about all your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications such as terfenadine, astemizole, cisapride, pimozide, halofantrine, and quinidine may interact with Noxafil 40mg Syrup and reduce effectiveness by causing undesirable side effects.
More Information about Noxafil 40mg Syrup
- Store Noxafil 40mg Syrup below (30°C).
- Protect from light and moisture.
How to consume Noxafil 40mg Syrup
It is necessary to take the syrup as directed by the physician. Shake the Noxafil 40mg Syrup well before use. Do not freeze and any syrup left in a bottle more than four weeks after it was first opened should not be used.
Safety Advices for Noxafil 40mg Syrup
Pregnancy
If you are pregnant, suspecting, or planning for the pregnancy, consult your doctor for more advice before taking Noxafil 40mg Syrup.
Breast Feeding
Taking Noxafil 40mg Syrup while breastfeeding may be unsafe because it passes into breast milk and affects the child. Do not breastfeed while taking this medicine.
Lungs
It is unknown whether Noxafil 40mg Syrup is safe for patients with lung problems. Inform your physician if you have lung disease before starting the treatment.
Liver
Inform your doctor if you have liver disease because the Noxafil 40mg Syrup should be used cautiously with a liver condition.
Alcohol
It is unknown whether consuming alcohol during treatment with Noxafil 40mg Syrup is safe. Please speak with your physician.
Driving
Some side effects of Noxafil 40mg Syrup may impair your ability to drive or operate machinery safely. It is unsafe to consume this drug.
Side Effects of Noxafil 40mg Syrup
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Serious
- Serious allergic reactions
- Skin rash or ulcers in the mouth, bruising, pale skin
- Yellow discoloration of eyes and skin, abdominal pain
Common
- Loss of appetite
- Low white blood cells
- Mild increase in blood pressure
- Diarrhea
- Nausea, vomiting
- Rectal discomfort
Word of Advice
Before taking this drug, your doctor will likely assess your medical history and perform any necessary tests to determine if it suits your specific condition. They will also provide instructions on taking the medication properly and monitoring your progress during treatment. If you have been prescribed Noxafil 40mg Syrup and have any questions or concerns about the medication or its potential side effects, be sure to discuss them with your physician for better clarification.
FAQs
Q 1. What conditions does Noxafil 40mg Syrup treat?
Noxafil 40mg Syrup treats and prevents invasive fungal infections caused by certain fungi, such as Aspergillus and Candida species. It is commonly prescribed for patients undergoing cancer chemotherapy, stem cell transplantation, or those with HIV/AIDS.
Q 2. What formulations are available for Noxafil 40mg Syrup?
Noxafil 40mg Syrup is available in different formulations, including oral suspension, syrup, delayed-release tablets, and intravenous (IV) infusion. The specific formulation and dosing will depend on the individual's condition and the physician's recommendation.
Q 3. Are there any precautions or contraindications for using Noxafil 40mg Syrup?
Individuals who have had an allergic reaction to other azole antifungal medications, those with certain heart conditions, liver problems, or abnormal potassium, magnesium, or calcium levels in the blood should exercise caution or avoid Noxafil 40mg Syrup. Always inform your physician about your medical history before initiating the treatment.
Q 4. Are there any side effects associated with Noxafil 40mg Syrup?
Common side effects of Noxafil 40mg Syrup include nausea, diarrhea, headache, and abdominal pain. Serious side effects are rare but may also include liver problems and allergic reactions. If you experience any concerning side effects, contact your physician immediately.
Q 5. Can pregnant or breastfeeding individuals take Noxafil 40mg Syrup?
Noxafil 40mg Syrup may not be safe during pregnancy, and its use during breastfeeding is not recommended. If you are pregnant, planning to become pregnant, or breastfeeding, discuss the risks and benefits of this drug with your doctor.
Q 6. Why is noxafil 40mg Syrup so expensive?
Each mL of oral noxafil 40mg Syrup contains 40 mg of posaconazole. The active ingredient per ml for syrup is high. Hence, it is so expensive when compared to other form of noxafil drug.
Fact Box of Noxafil 40mg Syrup
Molecule name: Posaconazole | Therapeutic class: Antifungal |
Pharmacological class: Azole derivative | Indications: Treatment of fungal infections |
References
- Merck Sharp & Dohme (UK) Limited, Electronic medicines compendium (EMC), [Revised on June 2023] [ Accessed on 20th July 2023], https://www.medicines.org.uk/emc/files/pil.5388.pdf
- Merck & Co. Inc, US FDA, [Revised on Dec 2016] [Accessed on 20th July 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2015/022003s018s020,0205053s002s004,0205596s001s003lbl.pdf
- KD Tripathi, Antifungal drugs, Essentials of Medical Pharmacology, 7th Edition, 2013, 795.
- Goodman & Gilman's, The Pharmacological Basis of Therapeutics, Antifungal agents, 12th edition, 2011, 1581.
Disclaimer
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