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Paclicad N Injection
Prescription Required
Salt Composition : Albumin Bound Paclitaxel
Manufacturer : CADILA PHARMACEUTICALS LTD
Origin of Medicine : India
1 Vial(s)
Introduction to Paclicad N Injection
Paclicad N Injection is an anticancer medicine. It treats breast cancer, non-small cell lung cancer, ovarian cancer, and AIDS (Acquired Immuno-Deficiency Syndrome). Cancer is a condition in which cells are dividing and growing fast and in an uncontrolled manner. This Injection may be given alone or in combination with other anticancer medicines. It should not be used for severe liver problems, uncontrolled infection, and low white blood cell or platelet count. This medicine is not recommended for adolescents and children under the age of 18. Talk to your doctor if you have heart disorders before taking this medicine. Administration of this medicine can cause serious allergic reactions. Use effective birth control during the treatment and for at least six months after the last dose. This Injection may harm patients suffering from alcoholism as this medicine contains alcohol.
Uses of Paclicad N Injection
- Ovarian cancer
- Breast cancer
- Non-small cell lung cancer
- AIDS-related Kaposi’s sarcoma
Therapeutic Effects of Paclicad N Injection
Paclicad N Injection binds to β-tubulin subunits of microtubules, interferes with interphase (a process involving cell growth) and mitotic functions (a process of cell division), and prevents the growth of cancer cells.
Interaction of Paclicad N Injection with other drugs
Inform your doctor about any prescribed medicines, over-the-counter medications, nutritional and vitamin supplements, or herbal products that you are taking or have taken before the treatment. Certain medications may interact with Paclicad N Injection and cause undesirable side effects.
More Information about Paclicad N Injection
- Keep Paclicad N Injection out of sight and reach of children.
- Do not store above 25°C.
How to consume Paclicad N Injection
It will be given to you by a doctor or nurse. Do not self-administer. Your doctor will decide the dose and dosage of the Paclicad N Injection.
Safety Advices for Paclicad N Injection
Pregnancy
Paclicad N Injection can harm your unborn baby. Tell your doctor if you are pregnant or planning to get pregnant before taking this injection.
Breast Feeding
Stop breastfeeding during the treatment with Paclicad N Injection. Consult your doctor for potential risks.
Lungs
It is unknown whether Paclicad N Injection can be given to patients with lung disorders. Please consult your physician for more advice.
Liver
It is contraindicated in patients with severe liver disorders. Inform your doctor if you have any liver disorders before taking Paclicad N Injection.
Alcohol
It is unsafe to consume alcohol with Paclicad N Injection.
Driving
The alcohol present in Paclicad N Injection may affect your ability to drive. Avoid driving if you feel unwell.
Side Effects of Paclicad N Injection
Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.
Serious:
- Serious allergic reactions (rash, swelling of face, lips, throat, or tongue, trouble breathing, and swallowing)
- Severe diarrhea
- Severe stomach pain
Common:
- Anemia, feeling tired
- Hair loss
- Burning, tingling, or numbness in your feet or hands
- Muscle and joint pain
- Vomiting, nausea
- Mouth or lip sores
- Infections
- Swelling of hands, feet, and face
- Bleeding
- Irritation at the injection site
- Low blood pressure
Word of Advice
Inform the doctor if the patient is allergic to this medication, liver, heart conditions, and other medication taken for different medical conditions before taking this medicine. Liver, blood pressure, and blood count should be monitored while taking this medication. Don't take this medication if the patient is planning for pregnancy or during pregnancy and in breastfeeding mothers, as it causes harmful effects on developing babies. Avoid driving and handling heavy machinery after taking this medication, as it can affect concentration and alertness.
FAQs
Q 1. Can Paclicad N Injection cause hair loss?
Yes, the common side effects of this medication are hair loss, and inform the doctor if there is excessive hair loss.
Q 2. How does Paclicad N Injection work?
It works by interfering with the microtubule structures, which help the cancer cells to divide and multiply and it slows the growth of cancer cells.
Q 3. Does Paclicad N Injection cause liver problems?
Yes, this medication is contraindicated in patients with severe liver disorders. Inform the doctor before starting this medication.
Q 4. Can I take Paclicad N Injection while driving?
It is unsafe to use this medication while driving because it can cause dizziness, lack of concentration, and alertness.
Q 5. What are the side effects of Paclicad N Injection?
The common side effects of Paclicad N Injection are anemia, hair loss, numb feet or hands, muscle pain, nausea, vomiting, infections, swelling, bleeding, irritation on the injection site, and low blood pressure.
Q 6. Can I take Paclicad N Injection during pregnancy?
It is unsafe to take this medication during pregnancy as it causes harmful effects on the developing baby. Inform the doctor if the patient is planning for pregnancy before starting this medication.
Fact Box of Paclicad N Injection
Molecule name: Albumin Bound Paclitaxel | Therapeutic class: Anti-neoplastics |
Pharmacological class: Microtubule Inhibitor | Indications: 1.Ovarian cancer 2.Breast cancer 3.Non-small cell lung cancer 4.AIDS-related Kaposi’s sarcoma |
References
- Hospira UK Limited, Electronic medicines compendium (EMC), [ Revised on March 2020] [ Accessed on 22nd June 2021], https://www.medicines.org.uk/emc/files/pil.3891.pdf
- Bristol-Myers Squibb Company, US Food and Drug Administration, [ Revised on April 2011] [ Accessed on 22nd June 2021], https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/020262s049lbl.pdf
- Spyridon Sideris et al; Efficacy of weekly paclitaxel treatment as a single agent chemotherapy following first-line cisplatin treatment in urothelial bladder cancer; Molecular and Clinical Oncology; Published on 17/03/2016; Accessed on 26/05/2022; https://www.spandidos-publications.com/10.3892/mco.2016.821
- Hiroko Machida et al; Efficacy of Modified Dose-dense Paclitaxel in Recurrent Cervical Cancer; American Journal of Clinical Oncology; Published on 01/10/2020; Accessed on 26/05/2022; https://pubmed.ncbi.nlm.nih.gov/28763329
- Dashan Ai MD et al; Comparison of 3 Paclitaxel-Based Chemoradiotherapy Regimens for Patients With Locally Advanced Esophageal Squamous Cell Cancer A Randomized Clinical Trial; JAMA; Published on 21/02/2022; Accessed on 26/05/2022; https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2789153
- Linyan Zhu, Liqun Chen; Progress in research on paclitaxel and tumor immunotherapy; Cellular & Molecular Letters; Published on 13/06/2019; Accessed on 26/05/2022; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6567594/
- Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Cytotoxic agents, 12th edition, 2011, 1707 - 1709.
- KD Tripathi, Essentials of Medical Pharmacology, Anticancer drugs, 7th edition, 2013, 865.
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