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Palozest 0.25mg Injection
Prescription Required
Salt Composition : Palonosetron
Manufacturer : ZEE LABORATORIES LTD
Origin of Medicine : India
1 Vial(s)
Introduction to Palozest 0.25mg Injection
Palozest 0.25mg Injection is an antiemetic drug belonging to the class of 5-HT3 receptor antagonists, containing the active ingredient Palonosetron. It is used to prevent and treat nausea, vomiting, or sickness caused by cancer treatments such as chemotherapy, radiotherapy, or after surgery. Nausea is characterised by stomach pain and the urge to vomit. The forcible voluntary or involuntary emptying of the stomach's contents through the mouth is known as vomiting.
The common side effects that are likely to occur with this medicine are hives, swollen face, breathing trouble and chest pain. Inform your healthcare provider if these side effects concern you or persist for longer than usual. It is given right away or later with anticancer medicines. It is usually given up to 24 hours while recovering from anaesthesia after surgery.
Talk to your physician if you have a history of repeated constipation, blockage in the bowel, heart problems, or imbalance of certain minerals in your blood (such as magnesium and potassium). This medicine should not be used if you are allergic to Palozest 0.25mg Injection. Tell your physician about all the medications you are taking recently, including herbal medicines and supplements, before taking Palonosetron.
Uses of Palozest 0.25mg Injection
Palozest 0.25mg Injection is a prescription medicine, and it is used to treat
- Postoperative nausea and vomiting.
- Chemotherapy induced nausea and vomiting.
Therapeutic Effects of Palozest 0.25mg Injection
Palonosetron is an Isoquinoline derivative that interacts with 5-HT3 receptor antagonists. It is a type of serotonin receptor antagonist, which works by blocking the action of serotonin in the body that induces nausea and vomiting. They are also effective in the prevention and treatment of nausea and vomiting in patients undergoing radiation therapy to the whole body or abdomen.
Interaction of Palozest 0.25mg Injection with other drugs
Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Palozest 0.25mg Injection and reduce effectiveness by causing undesirable side effects.
More Information about Palozest 0.25mg Injection
- Store Palozest 0.25mg Injection in the original package at room temperature (25°C). Do not freeze.
- Keep it out of reach from children and pets.
- It is important to get the dose at the scheduled time. If you missed the schedule, contact your doctor and reschedule the dose.
How to consume Palozest 0.25mg Injection
The medicine will be administered to you by a qualified healthcare professional in a hospital setting. This injection will be given intravenously into a vein in your arm or hand. Do not self-administer this medicine. The dose of the injection will be decided by your doctor based on your disease condition and other factors. Palozest 0.25mg Injection is usually given about 30 minutes before you receive your anti-cancer medicine (chemotherapy) or right before anaesthesia for surgery. If you are taking palonosetron as an oral tablet, it should be swallowed whole with a glass of water, with or without food, as directed by your healthcare provider. Do not crush, chew, or break the tablet before swallowing it.
Safety Advices for Palozest 0.25mg Injection
Pregnancy
It is unknown whether Palozest 0.25mg Injection can be administered during pregnancy. Consult your doctor if you are pregnant or planning for pregnancy during the treatment.
Breast Feeding
It is unsafe to breastfeed during the treatment with this injection because it may cause harm to the baby. Please consult your doctor before breastfeeding.
Lungs
It is unknown whether Palozest 0.25mg Injection can be administered to patients with lung problems. Consult your doctor if you have any lung diseases before starting the treatment.
Liver
It is unknown whether Palozest 0.25mg Injection can be administered to patients with liver disorders. Inform your physician if you have any liver problems before starting treatment with Palonosetron.
Alcohol
It is unknown whether consuming alcohol interacts with Palozest 0.25mg Injection. Please consult your doctor for more advice.
Driving
It is unsafe to drive vehicles or operate heavy machinery after taking Palozest 0.25mg Injection because Palonosetron contains a small amount of alcohol which may cause dizziness and impair your concentration.
Side Effects of Palozest 0.25mg Injection
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Common:
- Headache
- Fatigue
- Dizziness
- Abdominal pain.
Serious:
- Allergic reactions
- Hives
- Swollen face
- Breathing trouble
- Chest pain
Word of Advice
Talk to your physician if you have a history of repeated constipation, blockage in the bowel, heart problems, or imbalance of certain minerals (such as potassium and magnesium) in your blood before taking Palozest 0.25mg Injection. Inform your doctor or nurse if you are taking any medicines that affect your heart beat because they could cause a heart beat problem when taken with Palonosetron solution for injection.
FAQs
Q 1. Where Palozest 0.25mg Injection can be administered?
Palozest 0.25mg Injection is usually administered as an injection into a vein (intravenous or IV injection).
Q 2. Who should not take an Palozest 0.25mg Injection?
Palozest 0.25mg Injection should not be taken by individuals who are allergic to it or its ingredients.
Fact Box of Palozest 0.25mg Injection
Molecule name: Palonosetron | Therapeutic class: Antiemetics |
Pharmacological class: 5-HT3 receptor antagonists | Indications:
|
References
- Accord Healthcare SLU, Electronic medicines compendium (emc), [Revised on Feb 2021] [ Accessed on 01st March 2023], https://www.medicines.org.uk/emc/files/pil.7235.pdf
- Fresenius kabi, US Food and Drug Administration, [Revised on Dec 2018] [Accessed on 01st March 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/208109s001lbl.pdf
- Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Treatment of disorders of bowel motility and water flux, 12th edition, 2011, 1341.
- KD Tripathi, Essentials of Medical Pharmacology, Antiemetic, prokinetic and digestant drugs, 7th edition, 2013, 669.
Disclaimer
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