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Paraprime Injection
Prescription Required
Salt Composition : Paracetamol
Manufacturer : INTAS PHARMACEUTICALS LTD
Origin of Medicine : India
1 Bottle Of 100ml
Introduction to Paraprime Injection
Paraprime injection contains the active constituent Paracetamol. It belongs to the class of medications called analgesics and antipyretics. It is used to relieve mild to moderate pain and to reduce fever. It is also used in combination with opioid analgesics to manage moderate to severe pain in adult and pediatric patients 2 years and older. It works by changing the way the body senses pain and by cooling the body.Â
Do not take Paraprime injection if you are allergic to Paracetamol or any other ingredients and if you suffer from severe liver disease. Inform your physician if you have liver disease and kidney problems. Notify your physician if you suffer from alcohol abuse. This medicine can be used during pregnancy and breastfeeding. However, inform your physician if you are pregnant or planning to get pregnant during the treatment.Â
The most common side effects of Paraprime injection are nausea, vomiting, headache, and insomnia in adult patients and nausea, vomiting, constipation, and pruritus in pediatric patients. This medicine will be administered to you by a healthcare professional. Do not self-administer the medicine.Â
Uses of Paraprime Injection
- Mild to moderate pain
- To reduce fever
- Moderate to severe pain in combination with opioid analgesics
Therapeutic Effects of Paraprime Injection
Paraprime injection reduces fever by inhibiting the formulation and release of hormone-like substances (prostaglandins) in the CNS and by inhibiting substances like endogenous pyrogens at the hypothalamic thermoregulator center. The analgesic activity of Paraprime injection is by inhibiting cyclooxygenase enzymes, particularly COX-3, in the CNS.
Interaction of Paraprime Injection with other drugs
Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional and vitamin supplements, and herbal products. Certain medications interact with Paraprime injection and reduce its effectiveness by causing undesirable side effects.
More Information about Paraprime Injection
- Do not store above 30°C
- Do not refrigerate or freeze.
- Protect the medicine from light and excessive moisture.
- Keep the medicine out of reach of children and pets
- If you missed the dosing schedule, inform your healthcare professional immediately and reschedule.
How to consume Paraprime Injection
Paraprime injection will be given by infusion into your veins. Your physician will decide the dose and duration of the infusion based on your disease condition. Do not self-administer the injection. This will take over 15 minutes. Generally, it is given every 4 to 6 hours or as needed to relieve pain or reduce fever.Â
Safety Advices for Paraprime Injection
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Pregnancy
 ÂParaprime injection can be used during pregnancy. However, inform your physician if you are pregnant, planning for pregnancy during the treatment.
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Breast Feeding
 ÂParaprime injection can be used during breast-feeding. Inform your physician if you are nursing a child.Â
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Lungs
 ÂParaprime injection can be used in patients with lung disorders. Inform your doctor if you have any lung diseases before starting the treatment.
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Liver
 ÂParaprime injection is contraindicated in patients with severe liver disease. Inform your physician if you have any liver diseases before initiating the treatment.
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Alcohol
 ÂIt is unsafe to consume alcohol during the treatment with Paraprime injection.
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Driving
 ÂParaprime injection does not affect your ability to drive and operate heavy machinery. Inform your physician if you face any symptoms that alter your concentration.
Side Effects of Paraprime Injection
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Common
- Itchy skin
- Constipation
- Nausea
- Vomiting
- Headache
- Insomnia
- Agitation
SeriousÂ
- Liver injury
- Pneumonitis
- Skin reactions
Word of Advice
This medicine is given through a needle placed in a vein. The medicine will be injected slowly over 15 minutes. A nurse or other health provider will give you this medicine. Do not consume alcohol while taking this injection. This medicine is safe when administered during pregnancy or breastfeeding. Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
FAQs
Q 1. Why would I need a Paraprime injection instead of the oral form?
Paraprime injection is typically used when immediate and precise pain relief is required or when oral administration is not possible, such as in case of nausea or vomiting. The injection allows for direct delivery of the medication into the bloodstream, resulting in a faster onset of action.
Q 2. How long does a Paraprime injection take to start working?
The onset of action for a Paraprime injection is generally faster compared to the oral form. Depending on the individual and the specific condition being treated, you may start experiencing pain relief within 5 to 10 minutes after the injection.
Q 3. Can I self-administer a Paraprime injection at home?
Healthcare professionals typically administer Paraprime injection in a clinical setting. Self-administration at home is generally not recommended unless specifically instructed and supervised by a healthcare provider.
Q 4. Can a Paraprime injection be used during pregnancy or breastfeeding?
Paraprime injection are generally considered safe during pregnancy and breastfeeding when used as directed. However, it is recommended to consult with a healthcare provider before using any medication during these periods to assess appropriate dosage and potential risks.
Q 5. Can a Paraprime injection be used for migraine headaches?
Paraprime injection can be used for migraine headaches, especially when oral medications are ineffective or tolerated due to severe nausea or vomiting. However, consulting with a healthcare provider for proper diagnosis and treatment options specific to your migraines is recommended.
Fact Box of Paraprime Injection
Molecule name: Paracetamol | Therapeutic class: Antipyretic, Analgesics |
Pharmacological class: Antipyretic, Analgesics | Indications: 1. Mild to moderate pain 2. To reduce fever 3. Moderate to severe pain in combination with opioid analgesics |
References
- Perfalgan 10mg/ml Solution for Infusion - Summary of Product Characteristics (SmPC) - (emc). www.medicines.org.uk. Published May 2021. Accessed May 16, 2023. https://www.medicines.org.uk/emc/product/60/smpc
- Acetaminophen Injection - Highlights of Prescribing Information.; 2021. Accessed May 16, 2023. https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/204957s000lbl.pdf
- KD Tripathi, Essentials of Medical Pharmacology, Nonsteroidal Anti-inflammatory Drugs and Antipyretics-Analgesics, 7th edition, 2013, 206-207.
- Goodman & Gilman’s, The Pharmacological Basics of Therapeutics, Anti-inflammatory, Antipyretic, and Analgesic Agents; Pharmacotherapy of Gout, 12th edition, 2011, 982-984.
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