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  ÂPentasa Rectal 1gm Suspension
Prescription Required
Salt Composition : Mesalazine
Manufacturer : FERRING PHARMACEUTICALS
Origin of Medicine : Czech Republic
7 Suppository(ies) In A Packet
Introduction to Pentasa Rectal 1gm Suspension
Pentasa rectal 1gm suspension is an anti-inflammatory drug that contains the active ingredient Mesalazine. It belongs to the family known as aminosalicylates. It is used to treat ulcerative colitis and Crohn’s ileocolitis. Ulcerative colitis and Crohn's ileocolitis are inflammatory bowel diseases (IBD). Ulcerative colitis mainly inflames the colon and rectum, causing diarrhea and rectal bleeding. Crohn's ileocolitis affects the small intestine and colon, involving deeper layers of the intestinal wall and leading to abdominal pain, weight loss, and complications.
Do not take Pentasa rectal 1gm suspension if you are allergic to Mesalazine, aspirin, salicylate, or any of its ingredients. Do not take this medicine if you have severe kidney disease or blood abnormalities while taking other medicines, such as sulphasalazine. This medicine is not for use in children under the age of 2. Inform your doctor if you have or have had a history of severe skin rash or skin peeling, blistering, and mouth sore.Â
Before initiating Pentasa rectal 1gm suspension treatment, your kidney and blood function will be assessed through tests. Your doctor will periodically monitor your liver, kidney, and blood health using blood and urine samples throughout your treatment. Pentasa rectal 1gm suspension use may lead to kidney stones, which could cause abdominal pain and blood in urine. Ensure proper hydration during Pentasa rectal 1gm suspension treatment.
Uses of Pentasa Rectal 1gm Suspension
- Ulcerative colitis
- Crohn’s ileocolitis
Therapeutic Effects of Pentasa Rectal 1gm Suspension
Pentasa rectal 1gm suspension works by reducing gut inflammation. It inhibits inflammatory compounds, counters free radicals, and adjusts the immune response, providing relief, promoting healing, and managing these conditions.
Interaction of Pentasa Rectal 1gm Suspension with other drugs
Inform your healthcare provider about all your medicines, including prescription, over-the-counter, nutritional, supplements, and herbal products. Certain medications, such as Lactulose, interact with Pentasa rectal 1gm suspension and reduce their effectiveness by causing undesirable side effects.
More Information about Pentasa Rectal 1gm Suspension
- Store Pentasa rectal 1gm suspension at 30°C.
- Protect the medicine from light and excessive moisture.
- Keep the medicine out of reach of children and pets.
- Always look for the expiration date before consuming it.
How to consume Pentasa Rectal 1gm Suspension
It comes in the form of a powder that needs to be mixed with water to create a suspension. Your healthcare provider will provide the exact dosing instructions, so it is crucial to follow their recommendations carefully. Generally, the suspension is taken three times a day, with at least 4 to 6 hours between doses. It can be taken with or without food. Shake the bottle well before each use and measure the prescribed dose using the provided oral syringe or dosing cup.
Safety Advices for Pentasa Rectal 1gm Suspension
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Pregnancy
 ÂDo not use Pentasa rectal 1gm suspension unless your doctor advises. Notify your healthcare professional if you are pregnant or planning to have a baby; think you may be pregnant so that your doctor may decide to give you this medicine if the expected benefits outweigh any potential risks.
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Breast Feeding
 ÂDo not use Pentasa rectal 1gm suspension unless your doctor advises. It is unknown whether Pentasa rectal 1gm suspension is excreted in breast milk. So, before starting the treatment, inform your doctor if you are breastfeeding. Contact your doctor for more information.
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Lungs
 ÂIt is unknown whether Pentasa rectal 1gm suspension is safe for patients with lung problems. Inform your physician if you have any lung disease before starting the treatment. Contact your doctor if you experience any lung-related symptoms.
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Liver
 ÂPentasa rectal 1gm suspension should be used cautiously in liver patients. Before starting the treatment, inform your physician about pre-existing liver conditions.
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Alcohol
 ÂIt is unknown whether consuming alcohol while taking Pentasa rectal 1gm suspension is safe or not. So, consult your doctor for more information.
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Driving
 ÂPentasa rectal 1gm suspension doesnt alter the capacity of driving or operating machinery. Contact your doctor for more information.
Side Effects of Pentasa Rectal 1gm Suspension
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Serious
- Unexpected nose bleeds, bleeding gums, bruising more easily
- Problems with kidney function
- Skin rash with flaking, boils or sore lips, or mouth
- Fever, sore throat
- Mouth or lip ulcers
- Spots underneath your skin
- Swollen ankles
Common
- Diarrhea
- Abdominal pain
- Nausea
- Headache
- Indigestion
- Bloating
- Muscle pain
Word of Advice
Follow the prescribed dosage and usage instructions provided by your healthcare professional. Inform your doctor about any known allergies or medical conditions you have before receiving Pentasa rectal 1gm suspension. Do not consume this medicine if you have kidney related condition. Before stating the treatment inform your doctor if you have liver condition as this medicine is cautiously recommended in such conditions. If you notice any unexpected or severe side effects, like an allergic reaction, seek immediate medical attention. Inform your healthcare professional about any other medications or supplements you are consuming to avoid potential drug interactions. If you have any concerns regarding the treatment, consult your healthcare professional for information.
FAQs
Q 1. How can I manage side effects while taking Pentasa rectal 1gm suspension?
If you observe any side effects while taking Pentasa rectal 1gm suspension, stay hydrated by drinking plenty of fluids. Your medical professional may also recommend over-the-counter or prescription medications to help manage your symptoms. You should contact your physician if your side effects are severe or persistent.
Q 2. Can I give the Pentasa rectal 1gm suspension to children?
No, Pentasa rectal 1gm suspension should not be given to children under 2 years of age. It's important to follow the recommended age guidelines and consult a healthcare professional for appropriate pediatric dosing and alternatives for younger children.
Q 3. Are there any dietary restrictions while taking Pentasa rectal 1gm suspension?
There are no specific dietary restrictions associated with these medications. However, it is recommended to maintain a healthy and balanced diet to support overall health and well-being.
Q 4. Can Pentasa rectal 1gm suspension be taken during pregnancy or while breastfeeding?
It is unsafe to consume Pentasa rectal 1gm suspension during pregnancy and breastfeeding. Notify your healthcare professional if you are pregnant or planning to have a baby think you may be pregnant. Your doctor will decide whether you should use this medicine.
Q 5. How long does it take for Pentasa rectal 1gm suspension to start working?
The time it takes for the Pentasa rectal 1gm suspension to start working varies from person to person. However, it is important to continue taking the medication as your healthcare provider prescribes to achieve optimal treatment outcomes.
Q 6. What are the side effects of Pentasa rectal 1gm suspension?
The common side effects of Pentasa rectal 1gm suspension are diarrhea, abdominal pain, nausea, headache, indigestion, bloating, and muscle pain.
Fact Box of Pentasa Rectal 1gm Suspension
Molecule name: Mesalazine | Therapeutic class: Anti-inflammatory drug |
Pharmacological class: Aminosalicylates | Indications: 1. Ulcerative colitis 2. Crohn’s ileocolitis |
References
- AbbVie Lt, Electronic Medicines Compendium (EMC), [Revised on May 2023] [Accessed on 31st August 2023], pil.2217.pdf (medicines.org.uk)
- Actavis Pharma, Inc., US Food and Drug Administration, [Revised on Sept 2015] [Accessed on 31st August 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2015/204412s006lbl.pdf
- KD Tripathi, Nonsteroidal Antiinflammatory Drugs and Antipyretic-Analgesics, Essentials of Medical Pharmacology, 8th Edition, 2019, 209-226.
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