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Pirfenex Tablet
Prescription Required
Salt Composition : Pirfenidone
Manufacturer : CIPLA LTD
Origin of Medicine : India
15 Tablet(s) In A Strip
Introduction to Pirfenex Tablet
Pirfenex 200mg tablet belongs to the medication class known as transforming growth factor inhibitors. It contains an active ingredient called Pirfenidone. It is used to treat idiopathic pulmonary fibrosis (IPF). Idiopathic pulmonary fibrosis is a type of lung disorder in which tissues of the lungs become scarred and inflamed, resulting in breathing difficulties. This medicine should not be used if you have severe liver disorders or kidney disorders, if you are taking fluvoxamine (which treats depression and obsessive-compulsive disorder), or if you are allergic to any of the ingredients of this medicine. Do not drink grapefruit juice while taking this medicine.Â
This medicine may cause gastrointestinal disorders and elevation in liver enzymes. If you experience any of these, temporary dodge or discontinuation may be required. Consult your doctor for more information. Contact your doctor immediately if you experience any abnormalities, such as dark or brown urine, bruises, bleeding than usual, or jaundice. This medicine is not recommended for adolescents and children under 18. Avoid smoking as it may reduce the efficacy of the Pirfenex 200mg tablet. Avoid exposure to sunlight, including sunlamps. Use sunscreen daily and cover your head, legs, and arms to reduce exposure to sunlight.
Uses of Pirfenex Tablet
- Idiopathic pulmonary fibrosis
Therapeutic Effects of Pirfenex Tablet
Pirfenex 200mg tablet works to reduce the production and accumulation of extracellular matrix (ECM) proteins, which contribute to the fibrosis and stiffening of lung tissue. This helps to slow the progression of the disease and improve lung function.
Interaction of Pirfenex Tablet with other drugs
Inform your healthcare provider about all your medicines, including prescription, over-the-counter, nutritional and vitamin supplements, vaccines, and herbal products. Certain medications, such as Ciprofloxacin and Fluvoxamine, may interact with the effects of Pirfenex 200mg tablet and reduce its effectiveness by causing undesirable side effects.Â
More Information about Pirfenex Tablet
- Keep the Pirfenex 200mg tablet out of sight and reach of children.
- Store at a temperature of 25°C
- Store in the original package
- Do not refrigerate
How to consume Pirfenex Tablet
Take Pirfenex 200mg tablet in a dose and duration prescribed by your doctor. Swallow the tablets whole with water. Take the tablet after a meal at the same time each day to reduce the side effects. Do not crush or chew the tablets. Do not drink grapefruit juice while taking this medication.
Safety Advices for Pirfenex Tablet
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Pregnancy
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Pirfenex 200mg tablet may cause harm to the unborn baby. Tell your doctor if you are pregnant or planning to get pregnant before taking this medicine.Â
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Breast Feeding
 ÂIt is not recommended while taking Pirfenex 200mg tablet. Because the medicine can pass into breast milk, potentially harming a nursing infant. Consult the doctor for more information.Â
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Lungs
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Consult your doctor if you experience any upper respiratory tract infection while taking Pirfenex 200mg tablet.
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Liver
  Notify your doctor if you have any past severe liver problems before starting the treatment. It is recommended to perform a liver function test because Pirfenex 200mg tablet should be used with caution in patients with liver disease.
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Alcohol
 ÂIt is unknown if drinking alcohol while taking a Pirfenex 200mg tablet is safe. Please speak with your physician.
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Driving
  Pirfenex 200mg tablet may cause dizziness or sleepiness. So it is unsafe to drive while you are under this treatment.Â
Side Effects of Pirfenex Tablet
Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.
Serious
- Severe allergic reactions (swelling of face, lips, or tongue, wheezing, feeling faint)
- Liver problems (yellowing of skin or eyes, dark urine, bruising, or bleeding)
Common
- Nausea, vomiting
- Loss of appetite, tiredness
- Diarrhea, indigestion
- Headache, dizziness
- Skin reactions after exposure to sunlight
- Infections
- Weight loss
- Difficulty sleeping
- Changes in taste
- Cough
- Stomach pain, constipation, feeling bloated, heartburn
- Itchy, dry skin
- Muscle pain, joint pain
- Chest pain, shortness of breath
Word of Advice
If you experience any symptoms mentioned as a side effect, consult your doctor immediately. Abnormalities, such as dark or brown urine, bruises, bleeding than usual, or jaundice, must be notified immediately to your doctor. Avoid smoking while taking Pirfenex 200mg tablet because it may reduce the effectiveness of the medicine. Avoid exposure to sunlight, including sunlamps. Use sunscreen daily and cover your head, legs, and arms to reduce exposure to sunlight. Before starting the treatment, it is recommended to perform a liver function test.
FAQs
Q 1. How does Pirfenex 200mg tablet work?
Pirfenex 200mg tablet works by reducing inflammation and fibrosis in the lungs. It inhibits the production of certain molecules that cause scarring and stiffening of the lung tissue.
Q 2. How long should I take Pirfenex 200mg tablet?
Pirfenex 200mg tablet is a long-term medication that is taken indefinitely for treating IPF. Anyways, the duration of treatment may vary depending on the individual patient's response to the medication and other factors.
Q 3. Who should not take Pirfenex 200mg tablet?
Pirfenex 200mg tablet is not recommended for pregnant or breastfeeding women and those with severe liver or kidney disease.
Q 4. What dosage of Pirfenex 200mg tablet should I take?
It is important to note that the dosage of Pirfenex 200mg tablet may vary based on factors such as the patient's age, weight, renal function, and other medications they may be taking. Dosage adjustments may be necessary based on side effects or changes in the patient's condition. As with all medications, it is important to follow the dosage instructions provided by your healthcare provider and to consult with them if you have any questions or concerns.
Q 5. What should I do if I miss a dose of Pirfenex 200mg tablet?
If you miss a dose of Pirfenex 200mg tablet, take it as soon as you remember. Skip the missed dose and continue with your regular dosing schedule.
Q 6. What tests should I take before starting the Pirfenex 200mg tablet?
Your doctor will recommend you to take a liver function test before starting the cycles with Pirfenex 200mg tablet to monitor the functioning level.
Fact Box of Pirfenex Tablet
Molecule name: Pirfenidone | Therapeutic class: Antifibrotic drugs |
Pharmacological class: Transforming growth factor inhibitor | Indication: Idiopathic pulmonary fibrosis |
References
- Roche Products Limited, Electronic medicines compendium (emc), [Revised on Nov 2020] [Accessed on 1st April 2023] https://www.medicines.org.uk/emc/files/pil.2731.pdf
- Genentech USA, Inc, US Food and Drug Administration, [Revised on Jan 2017], [Accessed on 1st April 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/208780s000lbl.pdf
- Pirfenex Tablets; Cipla Ltd; Ciplamed; Accessed on 1st April 2023; https://www.ciplamed.com/content/pirfenex-tablets
Disclaimer
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