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Psien 500mg Tablet
Prescription Required
Salt Composition : Mycophenolate Mofetil
Manufacturer : BIOCON LTD
Origin of Medicine : India
10 Tablet(s) In A Strip
Introduction to Psien 500mg Tablet
Psien 500mg Tablet is an immunosuppressant with an active ingredient called Mycophenolate mofetil. It belongs to the inosine monophosphate dehydrogenase (IMPDH) inhibitor category. This medicine is used to prevent organ rejection in individuals who have previously received an organ transplant (such as kidney, heart, or liver transplantation). It is prescribed as part of a combination therapy that includes other immunosuppressive drugs.
This drug is contraindicated during pregnancy due to the risk of birth defects and miscarriage. It should not be advised in pregnant women unless there are no relevant alternatives and the potential benefits outweigh the risks. Women of birthing age are highly advised to use effective contraception while taking this tablet to prevent pregnancy. Live vaccines should not be administered while a person is taking a Psien 500mg Tablet due to reduced vaccine effectiveness and the risk of infection. Individuals taking this drug should not donate blood during treatment and at least six weeks after stopping treatment. It ensures that the medication has been adequately cleared from the body before donating blood.
It is generally advised not to take this medicine if you are allergic to the drug or any other ingredients. Inform your doctor of liver or heart disease before initiating the treatment. As this drug reduces the body's immune defenses, it can increase the chance of skin cancer. Individuals must take precautions to limit their exposure to sunlight and ultraviolet (UV) light. Seek your doctor immediately if you develop any bruising under the skin, fever, unexplained tiredness, dizziness, yellowing of the skin or eyes, vision impairment, reduced urine output, and seizures after taking this medicine. Psien 500mg Tablet is an immunosuppressive medication. It may affect the infant's developing immune system and should be avoided in breastfeeding. In some cases, alternative medications with a more favorable safety profile during breastfeeding may be considered.
Uses of Psien 500mg Tablet
- Prevent organ transplant rejections.Â
Therapeutic Effects of Psien 500mg Tablet
Psien 500mg Tablet works by inhibiting the enzyme inosine monophosphate dehydrogenase (IMPDH) and reducing the production of guanosine nucleotides. MMF specifically affects the proliferation of activated T and B lymphocytes. These lymphocytes are key players in the immune response that can lead to the rejection of a transplanted organ.
Interaction of Psien 500mg Tablet with other drugs
Inform your doctor about all your medicines, such as over-the-counter medications, prescription medications, vaccinations, nutritional and vitamin supplements, and herbal products. Certain groups of medications may interact with the effects of Psien 500mg Tablet and reduce its effectiveness by causing undesirable side effects.
More Information about Psien 500mg Tablet
- Store Psien 500mg Tablet at room temperature between (15°C to 30°C)
- Keep the medicine away from the reach of children and pets.
How to consume Psien 500mg Tablet
It is an orally available prescription drug. Your physician will decide the dose and duration of the treatment based on your disease condition, severity, and other factors. Always take Psien 500mg Tablet as prescribed by your doctor. Do not open, crush, break, or chew the medicine.Â
Safety Advices for Psien 500mg Tablet
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Pregnancy
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Psien 500mg Tablet is known to have harmful effects on the developing fetus and is generally not prescribed for use during pregnancy unless the benefits outweigh the risks.
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Breast Feeding
 ÂPsien 500mg Tablet is not recommended for breastfeeding mothers because small amounts of the drug can pass into the mother's milk and affect the nursing baby.
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Lungs
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Psien 500mg Tablet should be cautiously administered in patients with lung diseases. Dose adjustments are necessary. Inform your physician if you have lung problems before initiating the therapy. Â
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Liver
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It is generally considered safe for individuals with liver disease, including those with liver transplants. The dosage and use of Psien 500mg Tablet may need to be adjusted based on the severity of liver impairment.Â
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Alcohol
 ÂIt is unsafe to consume alcohol when taking Psien 500mg Tablet because it may cause excessive drowsiness or liver problems.
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Driving
  Driving vehicles or operating machinery while taking Psien 500mg Tablet is unsafe because it may cause drowsiness and vision problems.Â
Side Effects of Psien 500mg Tablet
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Serious
- Infections, fever, or sore throat
- Unusual bleeding or bruising
- Low blood cell count
- Severe allergic reactions
Common
- Higher risk of developing lymphoma and other cancers
- Nausea, abdominal pain
- Diarrhea
- Constipation
- Loss of appetite
- Shortness of breath
- Weight loss
- Increased heartbeat
- Headache
- Blood pressure problem
- Anaemia
Word of Advice
It is necessary to take the prescribed dose exactly as instructed by your doctor. Inform your doctor about all the medications (prescription, over-the-counter, and herbal) you are taking, as they can interact with this drug. If you plan to conceive or suspect you might be pregnant while taking Psien 500mg Tablet, it is important to consult your doctor immediately. They may suggest switching to alternative medications that are safer during pregnancy or adjusting your treatment plan.
FAQs
Q 1. Can I breastfeed while taking Psien 500mg Tablet?
Breastfeeding is generally not recommended while taking Psien 500mg Tablet. This drug can pass into the mother's breast milk and may hurt the nursing infant. Consult your doctor about breastfeeding if you are taking this tablet.
Q 2. How does Psien 500mg Tablet work?
Psien 500mg Tablet suppresses the immune system, preventing it from attacking the transplanted organ. It inhibits the activity of certain immune cells involved in the rejection process.
Q 3. What will happen if I stop taking Psien 500mg Tablet suddenly?
Stopping your treatment all of a sudden may cause your condition to become worse. Do not stop taking Psien 500mg Tablet without consulting your doctor.
Q 4. How should I take Psien 500mg Tablet?
Follow the instructions advised by your doctor or the medication label. Psien 500mg Tablet is taken orally with food to improve absorption. It should be swallowed, not chewed or broken.
Q 5. Can I drink alcohol while taking Psien 500mg Tablet?
It is highly recommended to limit or avoid alcohol consumption while taking Psien 500mg Tablet. Alcohol can interact with the medication, increasing the risk of side effects or interfering with its effectiveness.
Q 6. Whether Psien 500mg Tablet can cause miscarriage?
Yes, Psien 500mg Tablet can cause miscarriage. If you have childbearing potential, use effective contraception before or during treatment and at least six weeks after discontinuing the medication. Discuss contraceptive options with your doctor properly.
Q 7. Can I get vaccinated during the treatment with Psien 500mg Tablet?
Live vaccines should be avoided while taking Psien 500mg Tablet due to the risk of infection. Inform your healthcare provider about your immunization history and consult them regarding the appropriate timing of vaccinations.
Fact Box of Psien 500mg Tablet
Molecule name: Mycophenolate mofetil | Therapeutic class: Immunosuppressants |
Pharmacological class: Inosine monophosphate dehydrogenase (IMPDH) inhibitor | Indications: Prevent organ transplant rejections |
References
- Roche Products Limited, European Medicine Consortium (EMC), [Revised on April 2022],[Accessed on 25/05/2023], https://www.medicines.org.uk/emc/files/pil.1103.pdf
- Genentech USA, Inc., [ Revised on Oct 2021] [ Accessed on 25/05/2023], https://www.gene.com/download/pdf/cellcept_prescribing.pdf
- S.E. Marshall, Immunological Factors in Disease, Davidson's Principles and Practice of Medicine, 22nd Edition, 2014, 71-96.
- KD Tripathi, Immunosuppressant Drugs, Essentials of Medical Pharmacology, 8th Edition, 2019,.937-945.
- Goodman & Gilman's, The Pharmacological Basis of Therapeutics, Inflammation, Immunomodulation, and Hematopoiesis, 12th Edition, 2011, 1014.
Disclaimer
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