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Rabishield 100IU Injection
Prescription Required
Salt Composition : Rabies Human Monoclonal Antibody
Manufacturer : SERUM INSTITUTE OF INDIA
Origin of Medicine : India
1 Vial(s) Of 2.5ml
Introduction to Rabishield 100iu Injection
Rabishield 100IU injection contain active components called Rabies human monoclonal antibodies. One of the primary benefits of it is that it provides immediate passive immunity against the rabies virus. This is especially important in high-risk exposure situations where waiting for the body to generate its antibodies through vaccination may need to be faster. can be particularly advantageous for individuals with weakened or compromised immune systems, such as those with HIV/AIDS or those undergoing immunosuppressive treatments. By neutralizing the virus at the site of exposure, it can significantly reduce the risk of rabies infection, especially when administered promptly after a high-risk exposure, like a bite from a rabid animal. Some people may be hesitant to complete the full course of rabies vaccinations due to the number of required doses or the discomfort associated with injections. It can help improve compliance because they provides immediate protection, potentially reducing anxiety about rabies exposure.
Rabishield 100IU injection may be contraindicated if a person has a known hypersensitivity or severe allergic reaction to any of its components. It should be avoided for low-risk exposure situations with minimal chances of rabies transmission. Its use during pregnancy and breastfeeding may be contraindicated due to limited study data, and potential risks and benefits should be carefully considered. It can be used in older individuals when indicated. When indicated, Rabishield 100IU injection can be used in children as part of rabies post-exposure prophylaxis.Â
Uses of Rabishield 100iu Injection
Rabishield 100IU injection are used for the following:
- Rabies Post-Exposure Prophylaxis (PEP)
Therapeutic Effects of Rabishield 100iu Injection
Rabishield 100IU injection ( Rabishield 100IU injection ) work by binding to the rabies virus and neutralizing it, providing immediate passive immunity to individuals exposed to the virus. This complements rabies vaccinations, as the body's immune response takes time to develop antibodies.
Interaction of Rabishield 100iu Injection with other drugs
Inform the doctor about your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Rabishield 100IU injection, reducing effectiveness by causing undesirable side effects.Â
More Information about Rabishield 100iu Injection
- Store at room temperature below 2°C to 8°C
- Keep away from moisture, heat, and light.
- It should not be frozen.
- Keep away from children and pets.
How to consume Rabishield 100iu Injection
Rabishield 100IU injection are primarily administered intramuscularly, typically at the site of the potential rabies exposure. The best route of administration depends on the individual's needs and preferences, but oral administration is typically the most convenient.
Safety Advices for Rabishield 100iu Injection
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Pregnancy
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There is limited information on the safety of Rabishield 100IU injection in pregnancy. It is important to consult your healthcare provider before taking it in pregnancy.
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Breast Feeding
 ÂIt is important to talk to your doctor before taking any Rabishield 100IU injection  if you are breastfeeding, as there is limited information on its safety.
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Lungs
  If you have lung diseases, talking to your doctor before taking Rabishield 100IU injection is important.
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Liver
  People with liver disease should consult their doctor before taking Rabishield 100IU injection.
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Alcohol
 ÂAlcohol consumption does not typically interact with Rabishield 100IU injection. However, consult a healthcare provider before taking it with alcohol
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Driving
  Rabishield 100IU injection  do not cause any known side effects that would impair driving ability. If you experience any side effects, such as nausea, or vomiting, and dizziness, consult your healthcare provider before taking it while driving.
Side Effects of Rabishield 100iu Injection
Rabishield 100IU injection  cause some side effects like all medications, although not everyone will experience them.Â
Serious:
- Allergic reactions, including anaphylaxis
Common:
- Injection site pain
- Swelling and redness
- Low-grade fever
Word of Advice
Check if the person is allergic to any Rabishield 100IU injection components or has had problems with similar treatments before. Give it soon after a potential rabies exposure because delays can make them less effective. Look at the person's health condition, especially if they have a weak immune system, as it might not work well in such cases. Consider carefully using it during pregnancy or breastfeeding to weigh potential risks and benefits. Keep a close eye on the person during and after the treatment, especially if they have other health problems. Understand if the person has received rabies vaccines before because it is often given with these vaccines. If someone faces multiple possible rabies sources, consider giving more of its doses. If the person is very young or old, consider their age and weight to decide how much to use.
FAQs
Q 1. What are the common side effects of Rabishield 100IU injection?
Common side effects may include pain at the injection site, swelling, redness, and low-grade fever.
Q 2. Can Rabishield 100IU injection completely replace rabies vaccinations?
No, Rabishield 100IU injection are typically used in conjunction with rabies vaccinations. While Rabishield 100IU injection provide immediate protection, vaccinations are necessary to stimulate the person's immune system for long-term immunity.
Q 3. Are Rabishield 100IU injection effective against all strains of the rabies virus?
Rabishield 100IU injection are designed to be effective against various rabies virus strains. They are selected for their ability to neutralize the virus, protecting in most cases.
Q 4. How quickly should Rabishield 100IU injection be administered after a potential rabies exposure?
To maximize their protective benefits, Rabishield 100IU injection are most effective when given as soon as possible after exposure, ideally within hours or days.
Q 5. What happens if someone misses a dose of Rabishield 100IU injection or a scheduled rabies vaccination during the PEP process?
It's important to follow the prescribed schedule and not miss any doses. If a dose is missed, consult with a healthcare provider to determine the appropriate course of action, which may include additional doses.
Q 6. Are there long-term side effects associated with Rabishield 100IU injection?
Long-term side effects of Rabishield 100IU injection are not common. Side effects, if they occur, are typically short-term and mild.
Fact Box of Rabishield 100iu Injection
Molecule name: Rabies human monoclonal antibodies | Therapeutic class: Immune Globulins / Immune Sera |
Pharmacological class: Monoclonal Antibodies (mAbs) | Indications:Â Rabies Post-Exposure Prophylaxis (PEP) |
References
- Sudarshan MK. World Health Organization 2018 Guidelines on Rabies Prophylaxis: Contentious Issues. Pediatr Inf Dis 2019;1(4):154–156, https://www.pidjournal.com/doi/PID/pdf/10.5005/jp-journals-10081-1226
- Thomas Moulenat et al., Purified Vero Cell Rabies Vaccine (PVRV, Verorab®): A Systematic Review of Intradermal Use Between 1985 and 2019, Trop. Med. Infect. Dis., 2020, 5, 40, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7157209/pdf/tropicalmed-05-00040.pdf
- Serum Institute of India Pvt Ltd, [Revised on 2021] [Accessed on 10th Oct 2023], https://www.seruminstitute.com/product_ind_rabishield.php
- Anwith, H S & Ravish, Haradanahalli & Ashwathnarayana, Doddabele, Safety of new indigenous human Rabies Monoclonal Antibody (RMAb) for Post Exposure Prophylaxis, Indian Journal of Community Health, 2018, 30, 196-201, https://www.researchgate.net/publication/328743661_Safety_of_new_indigenous_human_Rabies_Monoclonal_Antibody_RMAb_for_Post_Exposure_Prophylaxis_Corresponding_Author_Citation_Article_Cycle
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