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Refra 5mg Tablet
Prescription Required
Salt Composition : Midodrine
Manufacturer : SANFEGAN BIOTECH PVT LTD
Origin of Medicine : India
15 Tablet(s) In A Strip
Introduction to Refra 5mg Tablet
Refra 5mg Tablet consists of the active ingredient Midodrine. This medication is primarily used to treat low blood pressure (hypotension). It belongs to a class of drugs known as alpha-1 adrenergic agonists, which constrict blood vessels and increase blood pressure. Refra 5mg Tablet is commonly prescribed for conditions such as orthostatic hypotension, a form of low blood pressure that occurs when standing up from a seated or lying position. It helps to improve symptoms such as lightheadedness, dizziness, and fainting associated with this condition. This medication should be used cautiously in individuals with severe kidney impairment or end-stage renal disease. Dosing adjustments may be necessary to prevent the accumulation of the drug or its metabolites.
You should not take the medication if you have a known allergy or hypersensitivity to Refra 5mg Tablet or its components. Before taking it, talk to your doctor if you have difficulty in urinating, cardiac diseases, eye problems resulting from diabetes, tumors in the adrenal glands, enlarged prostate, severe kidney disease, high blood pressure, slow pulse, and thyroid disorders. Refra 5mg Tablet should not be used in individuals with severe heart conditions, such as unstable angina, congestive heart failure, or recent myocardial infarction (heart attack). The medication can increase cardiac workload and may not be well-tolerated in these cases.
Uses of Refra 5mg Tablet
- Treatment of orthostatic hypotension (low BP when a person stands up from a seated or lying)
Therapeutic Effects of Refra 5mg Tablet
The therapeutic effect of Refra 5mg Tablet is to increase blood pressure in individuals with low blood pressure or orthostatic hypotension. Acting as an alpha-1 adrenergic agonist and constricting blood vessels, helps to raise peripheral vascular resistance and improve blood flow to vital organs, particularly the brain. This medication enhances blood pressure and offers a therapeutic benefit by improving quality of life, functional capacity, and cognitive function in individuals with orthostatic hypotension.
Interaction of Refra 5mg Tablet with other drugs
Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Refra 5mg Tablet and reduce effectiveness by causing undesirable side effects.
More Information about Refra 5mg Tablet
- Refra 5mg Tablet should be stored at room temperature between 68°F to 77°F (20°C to 25°C).
- Keep in the original package.
- Keep away from light, moisture, and heat.
- Keep away from children and pets.
- Avoid taking double doses for missed doses.
How to consume Refra 5mg Tablet
Refra 5mg Tablet is taken orally as a Tablet 10'S and should be taken with or without food. The Tablet 10'Ss should be swallowed whole with water and not crushed, chewed, or opened. The dosage and duration of treatment will depend on the individual's condition and response to the medication and should be determined by a healthcare provider.
Safety Advices for Refra 5mg Tablet
Pregnancy
The safety of using Refra 5mg Tablet during pregnancy has not been established. Limited studies are available regarding the use of this medication in pregnant women, so it is recommended to use caution and consult a doctor before considering its use during pregnancy.
Breast Feeding
It is unknown whether Refra 5mg Tablet is excreted in milk. So it is better to consult a healthcare provider if you are a breastfeeding mother before taking this medication.
Lungs
If you have a history of lung or respiratory disorders, it is important to consult your healthcare provider before taking Refra 5mg Tablet.
Liver
Refra 5mg Tablet is predominantly metabolized in the liver. While it is generally considered safe for individuals with normal liver function, caution is advised in patients with liver impairment or liver disease. If you have a pre-existing liver condition or impaired liver function, informing your healthcare provider before starting Refra 5mg Tablet is crucial.
Alcohol
It is generally recommended to avoid or limit alcohol consumption while taking Refra 5mg Tablet. Alcohol can interact with this medication and potentially increase the risk of side effects
Driving
Patients receiving Refra 5mg Tablet should be advised to avoid driving or operating machinery if they experience side effects such as fatigue, dizziness, or blurred vision, impairing a patient's ability to drive or operate machinery safely.
Side Effects of Refra 5mg Tablet
Refra 5mg Tablet can cause side effects like all medications, although not everyone who takes it will experience them.
Serious:
- Chest pain or tightness
- Rapid or irregular heartbeat
- Severe dizziness or lightheadedness
- Shortness of breath or difficulty breathing
- Severe headache
- Blurred vision or other vision changes
- Fainting or loss of consciousness
- Signs of an allergic reaction (e.g., hives, swelling, difficulty breathing)
Common:
- Scalp tingling or piloerection (goosebumps)
- Itching or rash
- Abdominal discomfort or pain
- Nausea
- Headache
- High blood pressure (especially when lying down)
Word of Advice
It is advised to use caution when using Refra 5mg Tablet in individuals with pre-existing heart conditions, as it may worsen symptoms. It should be used cautiously in individuals with urinary retention and kidney patients. Any signs of hypersensitivity or allergic reactions should be promptly addressed. This medication should be avoided in individuals with pheochromocytoma (a type of adrenal gland tumor) and peripheral vascular disease. Medication should not be discontinued abruptly. Pregnancy and breastfeeding are not recommended during treatment before consulting a doctor. It is contraindicated in individuals with hypertension (high blood pressure) or other hypertensive states where a significant increase in blood pressure would be detrimental. This medication should be avoided in heart conditions, such as unstable angina, congestive heart failure, or recent myocardial infarction (heart attack). Pediatric and geriatric populations require close monitoring when using Refra 5mg Tablet.
FAQs
Q 1. Can I take Refra 5mg Tablet if I have a history of heart disease?
Refra 5mg Tablet should be used cautiously in individuals with pre-existing heart conditions, as it may exacerbate certain cardiac conditions. It is important to discuss your medical history with your healthcare provider, who will evaluate the risks and benefits of using this medication in your specific case.
Q 2. Can I drink caffeinated beverages while taking Refra 5mg Tablet?
Caffeine can stimulate the cardiovascular system and may interact with Refra 5mg Tablet. Limiting or avoiding excessive consumption of caffeinated beverages while taking this medication is recommended. However, individual tolerance and response may vary, so it's best to consult your healthcare provider for personalized advice.
Q 3. Can I take Refra 5mg Tablet if I have diabetes?
Refra 5mg Tablet can potentially affect blood sugar levels and may require monitoring or adjustments in diabetic patients. It is important to inform your healthcare provider if you have diabetes, as they can guide how to manage blood sugar levels while taking it.
Q 4. Can I work or engage in physically demanding activities while taking Refra 5mg Tablet?
Refra 5mg Tablet can cause dizziness or lightheadedness as a side effect. If you experience these symptoms, it is important to exercise caution when engaging in activities that require alertness and coordination. Depending on individual response to the medication, a person may need to adjust the work or physical activity routine. Discuss any concerns with your healthcare provider.
Q 5. Can I take Refra 5mg Tablet if I plan to undergo surgery or dental procedures?
It is important to inform your healthcare provider, surgeon, or dentist about using Refra 5mg Tablet. They can evaluate the potential interactions with anesthesia and make appropriate recommendations. It may be necessary to adjust the timing of your this medication doses before and after the procedure.
Fact Box of Refra 5mg Tablet
Molecule name: Midodrine | Therapeutic class: Vasopressor Agent |
| Pharmacological class: Alpha-1 adrenergic agonists | Indications: Orthostatic hypotension |
References
- Goodman & Gilman’s, The Pharmacological Basics of Therapeutics, Adrenergic agonists and antagonists, 12th edition, 2011,294-295.
- Tillomed Laboratories Ltd, Electronic medicines compendium (EMC), [Revised on 16 November 2022], [Accessed on 30th May 2023], https://www.medicines.org.uk/emc/files/pil.12496.pdf
- Shrine US, US Food and Drug Administration, [Revised on Jan 2017] [Accessed on 30th May 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/019815s010lbl.pdf
Disclaimer
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