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Rotarix Injection
Prescription Required
Salt Composition : Rotavirus Vaccine
Manufacturer : GLAXO SMITHKLINE PHARMACEUTICALS LTD
Origin of Medicine : India
1 Vial(s)
Introduction to Rotarix Injection
Rotarix injection contains active components as Rotavirus vaccine. It is a vaccine that helps protect against rotavirus infection. Rotavirus is a highly contagious virus that can cause severe diarrhea, vomiting, fever, and dehydration, especially in young children. This vaccine has significantly reduced the incidence of rotavirus-related hospitalizations and complications, especially severe diarrhea and dehydration. Rotarix injections are typically included in many countries' routine childhood immunization schedules. The primary goal of rotavirus vaccination is to prevent severe gastroenteritis caused by rotavirus. Widespread vaccination against rotavirus protects vaccinated children and contributes to herd immunity.
It should not be used by individuals with a known hypersensitivity or allergy to it or its components. Intussusception is a rare medical condition where one part of the intestine telescopes into another part. There is a small increased risk of intussusception following rotavirus vaccination, particularly after the first dose. Children with severe immunodeficiency disorders, such as severe combined immunodeficiency (SCID), are generally contraindicated from receiving live attenuated vaccines like Rotarix injections. In some cases, if there is a household contact with a known severe immunodeficiency disorder, healthcare providers may advise against vaccinating an infant with a live attenuated vaccine like Rotarix injection due to the theoretical risk of shedding the vaccine virus to the immunocompromised individual.Â
Uses of Rotarix Injection
Rotarix injection is used in the following:
- Rotavirus disease
Therapeutic Effects of Rotarix Injection
Rotarix injections work by introducing weakened forms of the virus into the body. These weakened strains stimulate the immune system to produce protective antibodies without causing the disease. If a vaccinated individual is later exposed to the rotavirus, their immune system recognizes and fights it, preventing severe diarrhea and related complications.
Interaction of Rotarix Injection with other drugs
Inform the doctor about your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with the Rotarix injection, reducing effectiveness and causing undesirable side effects.Â
More Information about Rotarix Injection
- Stored at room temperature from 2°C and 8°C
- Keep away from moisture, heat, and light.
- It should not be frozen.
- Keep away from children and pets.
How to consume Rotarix Injection
The Rotarix injection is administered orally in liquid drops or an oral syringe. This mode of administration is well-suited for infants and young children and involves giving the vaccine by mouth. The vaccines are typically given at specific intervals, following a recommended dosing schedule, to ensure optimal protection
Safety Advices for Rotarix Injection
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Pregnancy
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Rotarix injection is typically not recommended during pregnancy. These vaccines are primarily intended for infants and young children. If there is a specific concern about rotavirus infection during pregnancy, it is best to consult a healthcare provider for personalized guidance.
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Breast Feeding
 ÂIf you are breastfeeding, discuss the potential risks and benefits of using the Rotarix injection with your healthcare provider.Â
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Lungs
  Rotarix injections are typically safe for individuals with lung conditions or respiratory issues. They do not contain live respiratory viruses or components that would pose a risk to the lungs. Consult with a healthcare provider if you have concerns or specific medical conditions.
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Liver
  Rotarix injections are generally considered safe for individuals with liver conditions. However, if you have concerns or specific liver-related health issues, it is advisable to consult with a healthcare provider for personalized advice.
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Alcohol
 ÂAlcohol consumption does not typically interfere with the safety or effectiveness of Rotarix injections. However, It's advisable to consult a healthcare provider.
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Driving
  The Rotarix injection is not known to impair one's ability to drive. However, some individuals may experience mild side effects, such as fatigue or dizziness, so it's advisable to consult a healthcare professional.
Side Effects of Rotarix Injection
Lactitol causes some side effects like all medications, although not everyone will experience them.Â
Serious
- Intussusception
- Allergic reactions
Common
- Irritability
- Mild diarrhea or vomiting
- Fever
- Soreness at the injection site
Word of Advice
After taking Rotarix injection evaluate individuals with moderate to severe acute illnesses, a history of gastrointestinal disorders, previous intussusception, severe immunodeficiency disorders, known allergies to vaccine components, households with immunocompromised members, and those with special medical conditions. Additionally, premature infants may warrant specific precautions, and individuals who have experienced significant adverse reactions to previous Rotarix injection doses may warrant specific precautions. It's crucial to adhere to recommended age and dosing schedules, maintain vaccine brand consistency throughout the series, and follow proper storage and handling guidelines. Open communication with healthcare professionals is essential to address any concerns or questions about vaccination precautions effectively and ensure the safe and effective use of Rotarix injections.
FAQs
Q 1. When should my child receive Rotarix injections, and how many doses are required?
The age at which your child should receive Rotarix injections and the number of doses depend on the specific vaccine used and local recommendations. The first dose is typically given around two months of age, followed by additional doses at specific intervals (e.g., 2, 4, and 6 months).
Q 2. What are the common side effects of Rotarix injections?
Common side effects of Rotarix injections are generally mild and can include irritability, mild diarrhea or vomiting, low-grade fever, and soreness at the injection site (for Rotarix, oral administration). Serious side effects are rare.
Q 3. Are Rotarix injections safe for premature infants?
Rotarix injections are generally safe for premature infants. However, healthcare providers may consider specific precautions for premature infants, so discussing this with your child's healthcare professional is essential.
Q 4. Can Rotarix injections be administered if my child has a cold or mild illness on the scheduled vaccination day?
In most cases, a mild illness, such as a cold, does not necessitate delaying rotavirus vaccination. However, if your child has a moderate to severe illness or a high fever, healthcare providers may recommend postponing the vaccine until they have recovered.
Q 5. Are there any specific travel considerations related to Rotarix injections?
Healthcare providers may discuss vaccination schedules and precautions to reduce the risk of illness during travel for infants traveling to regions with a high prevalence of rotavirus infection. Discuss your travel plans with your child's healthcare professional.
Q 6. How long does the protection from Rotarix injections last?
The duration of protection can vary, but Rotarix injections provide strong protection during the first few years of life, which is when children are most vulnerable to severe rotavirus infections. Booster doses are not typically required.
Fact Box of Rotarix Injection
Molecule name:Â Rotavirus vaccine | Therapeutic class: Immunological Agents |
Pharmacological class: Live Attenuated Viral Vaccines | Indications: Preventing rotavirus infection |
References
- GlaxoSmithKline Limited; European medicines compendium (EMC); [Revised on 31st Oct 2022]; [ Accessed on 6th September 2023] https://www.medicines.org.uk/emc/product/2739/smpc#grefÂ
- GlaxoSmithKline Limited); U.S Food and drug administration; [Revised on 11th July 2022]; [ Accessed on 6th September 2023]; https://www.fda.gov/vaccines-blood-biologics/vaccines/rotarix#:~:text=Indication%3A,to%2024%20weeks%20of%20age.Â
- Vesikari T. Rotavirus vaccination: a concise review; Clinical microbiology and infection; Published on October 2012 [Accessed on 6th September 2023]https://pubmed.ncbi.nlm.nih.gov/15246619/#:~:text=No%20side%20effects%20were%20seen,doses%2C%20depending%20on%20vaccine%20titer.Â
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