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Rybrevant 350mg Injection
Prescription Required
Salt Composition : Amivantamab
Manufacturer : JANSSEN-CILAG PHARMACEUTICALS
Origin of Medicine : Belgium
1 Vial(s)
PAP Information : Buy 4, Get 1 Free. Contact us for latest updates
Program Overview: JANSSEN-CILAG PHARMACEUTICALS, Patient Assistance Program (PAP) is dedicated to helping patients in need of Rybrevant 350mg injection. The program aims to provide eligible patients with access to the medication at a more affordable cost.
Program Benefits: Purchase four vials of Rybrevant 350mg injection and you will receive one free additional vial. Therefore, if eligible, you will have to pay only Rs.3,54,600 for five vials, which is Rs.70,920 per vial.
With MrMed's MRP discount of Rs.9850 per vial and janssen-cilag’s PAP program, the overall savings is over 1.3 lakhs.
Contact us for the latest updates on this exclusive offer.
Eligibility Criteria: To qualify for the Rybrevant Patient Assistance Program (PAP), you must meet specific criteria, including having a valid prescription for Amivantamab 350mg from a medical oncologist and being an Indian patient with a valid identity card. Eligibility is determined based on the diagnosed condition and program-specific requirements.
Contact Information: If you have any questions or need assistance with the application process, our dedicated patient support team is here to help. You can reach us by phone at 89391 69999 or email us at [email protected].
Please note that MrMed is not involved in the PAP program. They offer free consultations to patients to provide information about the program. Patients eligible for the PAP program by janssen-cilag can avail of it without having to purchase the medication from MrMed.
Patient Assistance Programs
Program Overview: JANSSEN-CILAG PHARMACEUTICALS, Patient Assistance Program (PAP) is dedicated to helping patients in need of Rybrevant 350mg injection. The program aims to provide eligible patients with access to the medication at a more affordable cost.
Program Benefits: Purchase four vials of Rybrevant 350mg injection and you will receive one free additional vial. Therefore, if eligible, you will have to pay only Rs.3,54,600 for five vials, which is Rs.70,920 per vial.
With MrMed's MRP discount of Rs.9850 per vial and janssen-cilag’s PAP program, the overall savings is over 1.3 lakhs.
Contact us for the latest updates on this exclusive offer.
Eligibility Criteria: To qualify for the Rybrevant Patient Assistance Program (PAP), you must meet specific criteria, including having a valid prescription for Amivantamab 350mg from a medical oncologist and being an Indian patient with a valid identity card. Eligibility is determined based on the diagnosed condition and program-specific requirements.
Contact Information: If you have any questions or need assistance with the application process, our dedicated patient support team is here to help. You can reach us by phone at 89391 69999 or email us at [email protected].
Please note that MrMed is not involved in the PAP program. They offer free consultations to patients to provide information about the program. Patients eligible for the PAP program by janssen-cilag can avail of it without having to purchase the medication from MrMed.
Introduction to Rybrevant 350mg Injection
Rybrevant 350mg injection contains the active substance Amivantamab. It is an antineoplastic drug that belongs to the class of medications called bispecific antibodies. It is used to treat a type of cancer called non-small cell lung cancer (NSCLC) that spreads to other parts of the body and has certain changes in a gene called EGFR. It is also used if it cannot be removed by surgery and has worsened during or after treatment with other anticancer medications.
Do not take this injection if you are allergic to amivantamab or any other ingredients of this medicine. Inform your physician if you have suffered from inflammation of your lungs or any other lung conditions before initiating the therapy. Report to your physician if you face any symptoms of sudden difficulty in breathing, cough, or fever that may suggest inflammation of the lungs. Rybrevant 350mg injection is not recommended for children or young people below 18 years of age.
Inform your physician if you have kidney problems, liver or lung problems before initiating the therapy. The common side effects of Rybrevant 350mg injection are rash, nail inflammation, musculoskeletal pain, shortness of breath, nausea, fatigue, swelling, inflamed and sore mouth, cough, constipation, and vomiting. This medicine may cause harm to the fetus hence use effective contraception during the treatment.
Uses of Rybrevant 350mg Injection
- Non-small cell lung cancer (NSCLC)
Therapeutic Effects of Rybrevant 350mg Injection
Rybrevant 350mg injection is an epidermal growth factor receptor (EGFR), and mesenchymal-epithelial transition factor (MET) targeted bispecific antibody that has been designed to recognize and attach to specific targets in the body. It targets two proteins found in cancer cells. It works by attaching to these proteins and may help to slow or stop your lung cancer from growing. It may also reduce the size of the tumor.
Interaction of Rybrevant 350mg Injection with other drugs
Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, recent vaccinations, nutritional and vitamin supplements, and herbal products. Certain medications may interact with Rybrevant 350mg injection and reduce its effectiveness by causing undesirable side effects.
More Information about Rybrevant 350mg Injection
- Store Rybrevant 350mg injection in the refrigerator (2°C to 8°C)
- Do not freeze
- keep the injection away from the reach of children and pets.
- If you have missed any dosing appointments, inform your doctor and schedule immediately.
How to consume Rybrevant 350mg Injection
It will be given to you by a doctor or nurse in a hospital or clinic setting trained in cancer chemotherapy. It is given as an intravenous infusion drip (into your vein) for several hours. Do not self-administer the injection. Your doctor will decide the dose and duration of the treatment based on your disease severity, body weight, and other factors.
Safety Advices for Rybrevant 350mg Injection
Pregnancy
Rybrevant 350mg injection is unsafe to administer in pregnant women because it may affect the fetus. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant. Using an effective birth control method during the treatment and for 3 months after your last dose is necessary.
Breast Feeding
Breastfeeding is not recommended in patients taking Rybrevant 350mg injection because the medicine passes into the breast milk in small amounts and may harm your baby.
Lungs
It is unknown whether Rybrevant 350mg injection can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.
Liver
It is unknown whether Rybrevant 350mg injection can be used in patients with liver disorders. Consult your doctor if you have any liver problems before starting the treatment.
Alcohol
It is unknown whether consuming alcohol is safe during the treatment with Rybrevant 350mg injection. Inform your doctor if you are a chronic drinker.
Driving
Rybrevant 350mg injection does not affect the ability to drive. If you feel tired or dizzy after taking this medicine, do not drive and consult your doctor for more advice.
Side Effects of Rybrevant 350mg Injection
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Common
- Swelling in the face, hands, and feet
- Inflammation in the nails
- Constipation
- Nausea, vomiting
- Inflamed and sore mouth
- Musculoskeletal pain
- Cough
- Shortness of breath
- Tiredness
Serious
- Severe rashes in the skin
- Eye pain and infection
- Inflammation of the lungs
- Infusion reactions
Word of Advice
To reduce skin problems, limit sun exposure during and for 2 months after treatment, wear protective clothing, and apply sunscreen and moisturizers that are alcohol-free regularly on your skin and nails while taking this medicine. Contact your doctor or nurse immediately if you have eye pain or vision problems. Consult your doctor before using contact lenses when you are taking this medicine. Do not breastfeed during the treatment and for 3 months after the last dose. Your doctor may advise you to take certain tests to check for the effectiveness of the therapy.
FAQs
Q 1. What are the infusion reactions that might happen during Rybrevant 350mg infusion?
Allergic reactions like itching. Swelling in your face or hands, tingling in mouth or throat, chest tightness, difficulty in breathing, fever, chills, cough, sore throat, body aches, unusual bleeding, bruising, or weakness should be informed to your doctor immediately.
Q 2. How long should I have to take Rybrevant 350mg injection?
Rybrevant 350mg injection is given as a cycle therapy. Your doctor will decide the dose and duration of the therapy based on your disease severity and condition.
Q 3. How long does Rybrevant 350mg infusion take?
Your first dose (the infusion on Day 1 and Day 2) can take about 4 to 6 hours. Infusions can get shorter starting on Week 2, and can take about 2 to 4 hours. Your doctor will decide the infusion rate based on your disease condition and other factors.
Q 4. What are the eye problems that may occur while taking Rybrevant 350mg injection?
Eye pain, dry eyes, eye redness, blurred vision, changes in the vision, itchy eyes, excessive tearing, sensitivity to light are the eye problems that may occur with this treatment. Inform your physician if you face any of the symptoms.
Q 5. Why should I avoid sun exposure during te treatment with Rybrevant 350mg injection?
Rybrevant 350mg injection can cause skin reactions. You should limit your time in the sun during your treatment with this medicine.
Q 6. Can I take vitamin supplements with Rybrevant 350mg injection?
Certain medications may interact with the effectiveness of Rybrevant 350mg injection including prescription, over-the-counter medicines, vitamin or nutritional supplements and herbal products. Inform your physician about all your medication history.
Fact Box of Rybrevant 350mg Injection
Molecule name: Amivantamab | Therapeutic class: Antineoplastics |
Pharmacological class: EGFR inhibitor & MET tyrosine kinase inhibitors | Indications: Treat non small cell lung cancer (NSCLC) |
References
- Rybrevant (amivantamab) 50mg/mL concentrate for solution for infusion - Patient Information Leaflet (PIL) - (emc). www.medicines.org.uk. [revised on 2021] [cited 2023 Apr 6]. Available from: https://www.medicines.org.uk/emc/product/13084/pil
- HIGHLIGHTS OF PRESCRIBING INFORMATION - amivantamab. [revised on 2021] [cited 2023 Apr 6]. Available from: https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/761210s000lbl.pdf
- Park K, Haura EB, Leighl NB, Mitchell P, Shu CA, Girard N, et al. Amivantamab in EGFR Exon 20 Insertion–Mutated Non–Small-Cell Lung Cancer Progressing on Platinum Chemotherapy: Initial Results from the CHRYSALIS Phase I Study. Journal of Clinical Oncology [revised on 2021 Aug 2] [cited 2023 Apr 6];39(30):JCO.21.00662. Available from: https://pubmed.ncbi.nlm.nih.gov/34339292/
Disclaimer
MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.
