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Sibolone 2.5mg Tablet
Prescription Required
Salt Composition : Tibolone
Manufacturer : SERUM INSTITUTE OF INDIA
Origin of Medicine : India
15 Tablet(s) In A Strip
Introduction to Sibolone 2.5mg Tablet
Sibolone 2.5 mg tablet contains the active constituent tibolone, which belongs to the group of medicines called synthetic steroid hormone. It is a hormone replacement therapy used in women to treat postmenopausal symptoms and prevent osteoporosis. Postmenopause occurs when a woman has not had a period of 12 months or more. In postmenopausal women, a decrease in estrogen levels may cause symptoms such as hot flashes (hot neck, face, and chest). Osteoporosis is a bone disease that is common in postmenopausal women and weakens and thins bones by reducing bone density.
Inform your doctor before taking Sibolone 2.5 mg tablet if you experience allergic (hypersensitive) to medicine. Notice your doctor if yo have pulmonary embolism (blood clot in lungs), history of heart disease (angina, myocardial infarction, stroke, or transient ischemic Attack) Before starting treatment with this medication, let your physician know if you have any liver, kidney, or uterine conditions. Inform your doctor if you have high blood pressure, diabetes, migraine or severe headaches, epilepsy, asthma, otosclerosis (a problem with hearing), or ever had breast cancer, vaginal bleeding, and thrombosis (blood clot in a vein). It is not recommended if you are a pregnant or breastfeeding woman.
Uses of Sibolone 2.5mg Tablet
- Treats estrogen deficiency symptoms
- Prevents osteoporosis (weak and brittle bones) in postmenopausal women.
Therapeutic Effects of Sibolone 2.5mg Tablet
Tibolone is a hormonal medication that works by imitating the actions of the hormones progesterone, estrogen, and testosterone found in the body. As a result, it alleviates menopausal symptoms by restoring hormone levels in the body. Additionally, Tibolone inhibits bone loss and fractures in postmenopausal women and prevents osteoporosis by restoring the body's estrogen levels.
Interaction of Sibolone 2.5mg Tablet with other drugs
Inform your healthcare provider about all your medicines, including prescription, over-the-counter, nutritional, supplements, and herbal products. Certain medications like fampridine interact with Tibolone and reduce their effectiveness by causing undesirable side effects.Â
More Information about Sibolone 2.5mg Tablet
- Store away from light & moisture.
- Keep Sibolone 2.5 mg tablet out of sight and reach of children.
How to consume Sibolone 2.5mg Tablet
Take a Sibolone 2.5 mg tablet as prescribed by your doctor. The suggested dose is one tablet daily, taken at the same time every day, before or after meals. Avoid breaking or chewing the tablet. Instead, swallow it whole with a glass of water.
Safety Advices for Sibolone 2.5mg Tablet
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Pregnancy
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Consult your doctor if you think you're pregnant or are planning to get pregnant. Do not take this medication during pregnancy as it may harm the unborn baby.
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Breast Feeding
 ÂDo not breastfeed while using a Sibolone 2.5 mg tablet , as it may be unsafe during breastfeeding.
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Lungs
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It is unknown whether Sibolone 2.5 mg is safe to be administered in patients with lung diseases. Inform your physician if you have any lung diseases before initiating the therapy.Â
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Liver
  Sibolone 2.5 mg tablet is used with caution if you have a history of liver diseases and requires dose adjustment.Â
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Alcohol
 ÂAvoid consuming alcohol while on treatment with Sibolone 2.5 mg tablet as it may increase the risk of breast cancer.
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Driving
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This medicine is not likely to affect the ability to drive and use any tools or machines.Â
Side Effects of Sibolone 2.5mg Tablet
Side effects are unwanted symptoms caused by medicines. Even though all medications cause side effects, not everyone gets them.
Serious
- High blood pressure
- Jaundice (yellowing of skin or eyes)
- Migraine-type headaches
Common
- Stomach pain
- Breast pain
- Vaginal bleeding, itching or irritation
- Abnormal hair growth
- Weight gain
- Postmenopausal hemorrhage
- Pelvic pain
- Cervical dysplasia (development of abnormal cells in cervix)
- Genital discharge
- Vaginal yeast infection
- Endometrial hyperplasia (excessive thickening of the uterus)
- Abnormal cervical smear
Word of Advice
It is suggested to inform your doctor if you have a history of allergic reactions to Sibolone 2.5 mg tablet to avoid life-threatening complications. Tell your doctor before the treatment commencement if you are pregnant or having liver, kidney, or uterine problems. Your doctor may prescribe you to regularly check your breasts for any changes in the nipple, dimpling of the skin, or lumps, and undergo regular breast screening and cervical smear tests while on treatment with this medicine.
FAQs
Q 1. What is the Sibolone 2.5 mg tablet prescribed for?
Sibolone 2.5 mg tablet is a synthetic steroid hormone used to treat estrogen deficiency symptoms and prevent osteoporosis (weak and brittle bones) in postmenopausal women.
Q 2. How does Sibolone 2.5 mg tablet work?
Sibolone 2.5 mg tablet works by imitating the effects of the body's progesterone, estrogen, and testosterone hormones. As a result, it reduces menopausal symptoms by balancing hormone levels in the body. In addition, Tibolone restores the body's estrogen levels, which prevents bone loss, fractures, and osteoporosis in postmenopausal women
Q 3. Can a pregnant woman take Sibolone 2.5 mg tablet ?
No, Sibolone 2.5 mg tablets should not be used during pregnancy or if you want to get pregnant. You should tell your doctor right away if you find out you're pregnant while taking this drug, and the medication should be stopped right away.
Q 4. Can alcohol be taken with a Sibolone 2.5 mg tablet ?
Taking alcohol is unsafe with Sibolone 2.5 mg tablet as it may increase the risk of breast cancer.
Q 5. Is Sibolone 2.5 mg tablet a contraceptive?
Sibolone 2.5 mg tablet is not a contraceptive. It is a hormone replacement therapy used in women to treat postmenopausal symptoms and prevent osteoporosis. Therefore, you are advised to use extra contraceptive methods to prevent pregnancy if you are under 50 or if it has been less than 12 months since your last period. However, if you have any concerns about this, consult your doctor.
Fact Box of Sibolone 2.5mg Tablet
Molecule name: Abacavir | Therapeutic class:Â Hormone replacement therapy |
Pharmacological class: Synthetic steroid hormone | Indications: 1. Treats estrogen deficiency symptoms 2. Prevents osteoporosis (weak and brittle bones) in postmenopausal women. |
References
- KD Tripathi, Essentials of Medical Pharmacology, Estrogens, Progestins and Contraceptives, 7th Edition, 2013, 306-311.
- Mercury Pharmaceuticals Limited., Electronic Medicines Compendium (EMC), [Revised on September 2020] [Accessed on 20th Sept 2023] https://www.medicines.org.uk/emc/files/pil.4429.pdf
- Steven R Cummings et al; The effects of tibolone in older postmenopausal women; published on Aug 2014; [Accessed on 20th Sept 2023]; https://pubmed.ncbi.nlm.nih.gov/18703472/
Disclaimer
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