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Solu Medrol 1gm Injection
Prescription Required
Salt Composition : Methylprednisolone
Manufacturer : PFIZER LTD
Origin of Medicine : United States of America
1 Vial(s) Of 8ml
Introduction to Solu Medrol 1gm Injection
Solu medrol 1gm injection is an anti-inflammatory drug belonging to the class of glucocorticoids, containing the active ingredient methylprednisolone. It is used to treat inflammatory or allergic conditions affecting the brain (caused by tumor or meningitis), lungs (caused by asthma, hypersensitivity, tuberculosis, or breathing in vomit or stomach contents), gut, and bowel (Crohn’s disease and ulcerative colitis). It treats rheumatic, skin, eye, and endocrine disorders. It is also used for the palliative management of cancers (leukemia and lymphoma) and the reduction of pain after surgery. In higher doses, it is used to treat flare-ups of symptoms of multiple sclerosis. This injection should not be used if you have a fungal infection, swelling of the brain due to malaria, traumatic brain injury, or if you recently had vaccinated or about to have any vaccination. The common side effects that are likely to occur with this medicine are headache, vision problems, poor wound healing, and bone weakness. Some serious side effects also include blood clots in the leg veins, lungs, and bleeding ulcers. Inform your healthcare provider if these side effects concern you or persist for longer than usual. Consult your doctor immediately for more advice.
This drug can increase the risk of certain eye problems, such as posterior subcapsular cataracts and glaucoma. These conditions can lead to vision loss if not treated properly. Additionally, corticosteroids can weaken the immune system, making individuals more susceptible to secondary ocular infections caused by fungi or viruses. Therefore, it is important to use corticosteroids at the lowest effective dose for the shortest possible duration to minimise the risk of these side effects.Â
If you experience any changes in your vision or eye discomfort while taking Solu medrol 1gm injection or any other corticosteroid, it is important to inform your doctor right away. Your healthcare provider will monitor your blood pressure, electrolyte levels, and kidney function closely while you are taking corticosteroids to prevent the side effects. In addition, all corticosteroids can increase calcium excretion, which can lead to osteoporosis and increased risk of fractures with prolonged use. Your doctor will prescribe calcium and vitamin D supplementation to help maintain bone health while taking corticosteroids. Tell your physician about all the medications you have been taking recently, including herbal medicines and supplements, before taking this injection.
Uses of Solu Medrol 1gm Injection
- Treatment of allergic conditions
- Rheumatic, blood, skin, eye, and endocrine disorders
- Leukemia and lymphomas (palliative management)
- Pain related to surgery (organ transplants)
- Multiple sclerosis
- Ulcerative colitis
Therapeutic Effects of Solu Medrol 1gm Injection
It works by binding to glucocorticoid receptors and inhibits the production of substances (such as prostaglandins) that lead to inflammation and allergies.
Interaction of Solu Medrol 1gm Injection with other drugs
Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Solu medrol 1gm injection and reduce effectiveness by causing undesirable side effects.Â
More Information about Solu Medrol 1gm Injection
- Store Solu medrol 1gm injection at controlled room temperature (20°-25°C).
- Protect from sunlight
- Keep it out of reach from children and pets.
How to consume Solu Medrol 1gm Injection
Solu medrol 1gm injection will be administered to you by a healthcare professional in a hospital setting. This injection will be given intramuscularly or intravenously into a vein in your arm. Do not self-administer this medicine. It is available in two strengths 40 mg/mL and 80 mg/mL. The dose of the injection will be decided by your doctor based on your disease condition and other factors.
Safety Advices for Solu Medrol 1gm Injection
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Pregnancy
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Solu medrol 1gm injection is not recommended for pregnant women as it may cause fetal harm. Consult your doctor if you are pregnant or planning for pregnancy during the treatment. A dose adjustment is suggested.
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Breast Feeding
 ÂBreastfeeding is not recommended in patients administered with a Solu medrol 1gm injection because it may harm your baby. Do not breastfeed during the treatment.Â
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Lungs
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It is not known whether Solu medrol 1gm injection can be administered to patients with lung problems. Consult your doctor if you have any lung diseases before starting the treatment.
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Liver
  Inform your doctor if you have any liver problems before taking Solu medrol 1gm injection. Regular monitoring of liver function tests is recommended.
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Alcohol
 ÂConsuming alcohol may affect the effectiveness of Solu medrol 1gm injection. Stop consuming alcohol if you are taking this medicine.
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Driving
  It is unsafe to drive vehicles or operate heavy machinery after taking Solu medrol 1gm injection, it may cause dizziness and impair your concentration.
Side Effects of Solu Medrol 1gm Injection
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Serious
- Allergic reactions (wheezing, swelling of face, difficulty breathing)
- Stomach pain spreading to your back, accompanied by vomiting and loss of consciousness
- Bleeding ulcers
- Infections
- Blood clots in the lung (chest pain, coughing up blood, breathlessness)
- Raised pressure within the skull (lack of energy, drowsiness)
- Blood clots in the leg vein
Common
- High blood pressure, headache
- Swelling
- Ulcers
- Vision problems
- Poor wound healing
- Round or moon-shaped face
- Slow growth in infants, children, and adolescents
- Muscle and bone weakness
- Feeling depressed or high, difficulty in thinking, memory loss
- Acne, bruising
- Thinning of skin
Word of Advice
Solu medrol 1gm injection can cause harm to a developing fetus or nursing baby, so it is important to notify your physician if you are pregnant, breastfeeding, or planning to have a baby. Grapefruit juice and grapefruit should be avoided by individuals taking this drug. This medicine can cause several side effects related to electrolyte and fluid balance. When given in large doses, these medications can increase blood pressure, cause salt and water retention, and increase the excretion of potassium. These effects are less likely to occur with prolonged use or high doses. To prevent these side effects, dietary salt restriction and potassium supplementation may be necessary.Â
FAQs
Q 1. Can I drive after receiving a Solu medrol 1gm injection?
It is generally unsafe to drive after receiving a Solu medrol 1gm injection. However, you may experience vertigo, dizziness, or drowsiness as a side effect, which may impair your ability to operate a vehicle or heavy machinery. It is important to wait until you feel fully alert and able to function normally before driving.
Q 2. What does Solu medrol 1gm injection do to your body?
Solu medrol 1gm injection works by suppressing the immune system and reducing the production of certain inflammatory chemicals in the body. This can help reduce the symptoms of cancer and the side effects of cancer treatment, such as pain, swelling, and nausea.
Q 3. What are the special precautions I should be aware of before starting treatment with Solu medrol 1gm injection?
Inform your doctor about your pre-existing conditions (heart, kidney, liver, hepatitis B, or lung disease) and vaccination history. It is necessary to consult a doctor if you are taking medicines for blood pressure.
Q 4. Can Solu medrol 1gm injection be used in combination with other drugs?
Yes, Solu medrol 1gm injection is often used in combination with other chemotherapy drugs to improve treatment outcomes.
Q 5. Whether Solu medrol 1gm injection is safe to use during pregnancy?
Solu medrol 1gm injection is not recommended during pregnancy and it is unsafe because it may harm a developing fetus. Women who are pregnant or planning to become pregnant should discuss their treatment options with their doctor immediately.
Q 6. What to avoid while taking Solu medrol 1gm injection?
Avoid consuming alcohol while taking Solu medrol 1gm injection as it may increase the risk of stomach irritation and other side effects.
Fact Box of Solu Medrol 1gm Injection
Molecule name: Methylprednisolone | Therapeutic class: Anti-inflammatory |
Pharmacological class: Glucocorticoids | Indications:Â 1. Treatment of allergic conditions 2. Rheumatic, blood, skin, eye, and endocrine disorders 3. Leukaemia and lymphomas (palliative management) 4. Pain related to surgery (organ transplants) 5. Multiple sclerosis 6. Ulcerative colitis |
References
- Pfizer Limited, Electronic medicines compendium (emc), [ Revised on April 2021] [ Accessed on 7th July 2021], https://www.medicines.org.uk/emc/files/pil.1550.pdf
- Pfizer, US Food and Drug Administration, [ Revised on Oct 2011] [ Accessed on 7th July 2021], https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/011856s103s104lbl.pdf
- Medrol, Food and Drug Administration, (Accessed on March 20, 2023),https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/011153s075lbl.pdf
- Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, ACTH, adrenal steroids, and pharmacology of the adrenal cortex, 12th edition, 2011, 1231.
- KD Tripathi, Essentials of Medical Pharmacology, Corticosteroids, 7th edition, 2013, 288.
Disclaimer
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