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Soraliz 200mg Tablet_203306
Soraliz 200mg Tablet_203306
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Soraliz 200mg Tablet

Prescription Required

Salt Composition : Sorafenib

Manufacturer : KHANDELWAL LABORATORIES PVT LTD

Origin of Medicine : India

MRP: 2399
Price : 1191
You Save : 1208 (50%)

30 Tablet(s) In A Bottle

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Molecule Name:  Sorafenib 

Therapeutic class: Antineoplastics

Pharmacological class: Multikinase inhibitors.

Indications: 

  1. Advanced renal cell carcinoma
  2. Advanced hepatocellular carcinoma
  3. Differentiated  thyroid carcinoma 
Dosage form:  TabletsHabit forming: No

Introduction to Soraliz 200mg Tablet

Soraliz 200mg Tablet belongs to the class of cancer medications known as multikinase inhibitors containing the active ingredient sorafenib. Soraliz 200mg Tablet is a medication primarily used in the treatment of advanced renal cell carcinoma (kidney cancer), hepatocellular carcinoma (liver cancer), and thyroid cancer.  

It is not recommended to take Soraliz 200mg Tablet if you are allergic to the active compound and other ingredients of the medicine. Speak with your doctor immediately if you experience skin rashes, heart problems, chest pain, bleeding problems, high blood pressure, or have had or are about to have surgery. It is not recommended for use in children and adolescents.  Patients with diabetes should have their blood sugar levels examined frequently to see whether the dosage of anti-diabetic medications needs to be changed to reduce the risk of low blood sugar. Your doctor will monitor liver function tests, fluid and electrolyte balance to help identify and manage potential side effects promptly.

It is not advised to use this medication while pregnant since it may harm the fetus Therefore, for women of reproductive age, it is recommended to get a pregnancy test before beginning this medication. It is preferable to keep using birth control for at least six months after treatment is finished. While receiving treatment, it is not advised to breastfeed your child because this medication might affect your baby's growth and development. This treatment may affect the fertility in both men and women, it is advised to consult your doctor before starting the therapy.

It is necessary to inform your doctor about all the medicines you are taking including prescription, over the counter drugs, vitamins and supplements.


Uses of Soraliz 200mg Tablet

  • Advanced renal cell carcinoma
  • Advanced hepatocellular carcinoma
  • Differentiated  thyroid carcinoma

Therapeutic Effects of Soraliz 200mg Tablet

Soraliz 200mg Tablet works by inhibiting multiple protein kinases involved in tumor cell proliferation and angiogenesis (the formation of new blood vessels that supply tumors). Specifically, it targets receptors for vascular endothelial growth factor (VEGF), platelet-derived growth factor (PDGF), and Raf kinases, which play key roles in cancer development and progression.  This stops the growth and spread of the tumor cells to other organs, as well the formation of blood vessels in the tumor cells.


Interaction of Soraliz 200mg Tablet with other drugs

Inform your healthcare provider about all the medicines you take, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Soraliz 200mg Tablet and reduce effectiveness by causing undesirable side effects. 


More Information about Soraliz 200mg Tablet

  • Store Soraliz 200mg Tablet Tablet in the original package at room temperature (20°C to 25°C).
  • Keep it out of reach from children

How to consume Soraliz 200mg Tablet

The medicine will be prescribed to you by a healthcare professional in a hospital setting. It is not recommended to take this medication with meals that are high in fat since this may reduce Soraliz 200mg Tablet's effectiveness. Take the pills at least one hour before or two hours after a high-fat meal if you plan to eat one.

The dose will be decided by your healthcare professional based on your conditions.  Avoid crushing, opening, or dissolving the tablet and swallow it whole with a glass of water. Take the Soraliz 200mg Tablet tablet at the same time every day.


Safety Advices for Soraliz 200mg Tablet

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Pregnancy

  

It is not recommended to take Soraliz 200mg Tablet during pregnancy as it may harm your unborn baby. It is necessary to inform your doctor if you are pregnant or planning to become pregnant

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Breast Feeding

  

It is unknown whether Soraliz 200mg Tablet  passes into the breast milk. It is not recommended to nurse a child during the therapy. This medication might affect your baby's growth and development. Please consult your doctor before breastfeeding. 

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Lungs

  

Consult your doctor if you have any lung diseases before starting the treatment with Soraliz 200mg Tablet Tablet.

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Liver

  

It is unknown whether Soraliz 200mg Tablet is safe in individuals with liver disorders.  Inform your physician if you have any liver problems before starting the treatment.

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Alcohol

  

Alcohol consumption can lead to hepatotoxicity and might alter the metabolism of Soraliz 200mg Tablet. Please consult your doctor for more advice.

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Driving

  

There is no proof that Soraliz 200mg Tablet will impair one's capacity to operate machinery or drive a car. However if you experience any of the side effects like dizziness, fatigue it is not advised to drive or operate heavy machinery. 


Side Effects of Soraliz 200mg Tablet

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

 Common:

  • Nausea
  • Vomiting
  • Fatigue
  • Diarrhoea
  • Alopecia
  • Hand foot skin reaction
  • Gut wall bleeding

Serious:

  • gastrointestinal perforation
  • abnormal heart rhythm (QT prolongation)
  • inflammation of the liver
  • breathing or swallowing difficulties
  • Stevens Johnsons Syndrome and toxic epidermal necrolysis
  • Decreased blood flow to the heart
  • Increased risk of bleeding (blood in urine, stool, vomit, cough, etc)

Word of Advice

Follow all instructions and dosing recommendations provided by your healthcare provider. Do not take more or less of the medication than prescribed. Report any new or worsening symptoms to your healthcare provider immediately, especially if they relate to your lungs, eyes, skin, liver, kidneys, heart, or bleeding. When undergoing this therapy, stay out of direct sunlight and wear sunscreen with an SPF of at least 50 before going outside. Soraliz 200mg Tablet should not be stopped without first talking to your doctor. Even if you feel better or see a change in your symptoms, you should still talk to your doctor before stopping Soraliz 200mg Tablet. It is recommended to inform your doctor about other anticancer drugs you have been taking.   It's critical to maintain a sufficient fluid intake because dehydration can exacerbate symptoms such as diarrhea and other gastrointestinal disorders. 

Remember to attend all scheduled appointments and follow-up visits with your healthcare provider to ensure your treatment is effective and any side effects are managed appropriately. 


FAQs

Q 1. Can Soraliz 200mg Tablet be taken during pregnancy or breastfeeding?

Soraliz 200mg Tablet may harm an unborn baby and should not be used during pregnancy. It is also not recommended while breastfeeding, as it may pass into breast milk and harm the nursing infant.

Q 2. What side effects does Soraliz 200mg Tablet typically cause?

Fatigue, weakness, diarrhea, nausea, vomiting, lack of appetite, hand-foot skin reaction (palmar-plantar erythrodysesthesia), rash, hair thinning, elevated blood pressure, and abnormal liver enzyme levels are common adverse effects of Soraliz 200mg Tablet.

Q 3. Will Soraliz 200mg Tablet cause hair loss?

Alopecia, or hair thinning or loss, is a possible adverse effect of Soraliz 200mg Tablet therapy, however it is less frequent than with certain other chemotherapy medications. While using Soraliz 200mg Tablet, not every patient will experience hair loss, and each patient's level of hair thinning will differ.


References

  1. Bayer (Pty) Ltd, [Revised on 22nd Apr 2016] [Accessed on  15th March 2024], https://www.bayer.com/sites/default/files/NEXAVAR_200_EN_PI.pdf
  2. Bayer HealthCare Pharmaceuticals Inc., US Food & Drug Administration, [Revised on Dec 2018] [Accessed on 15th  March 2024]], https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/021923s020lbl.pdf
  3. Bayer AG, European Medicines Compendium (emc), [Revised on April 2023], [Accessed on  15th March 2024], https://www.medicines.org.uk/emc/files/pil.226.pdf
  4. Zentiva Pharma UK Limited,  Medicines Compendium (emc), [Revised on April 2022], [Accessed on  15th March 2024] https://www.medicines.org.uk/emc/files/pil.13098.pdf
  5. KD Tripathi, Anticancer Drugs, Essentials of Medical Pharmacology, 8th Edition, 2019, 915-936.

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