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SPNIB 70MG TABLET_201145_1
SPNIB 70MG TABLET_201145_2
SPNIB 70MG TABLET_201145_3
SPNIB 70MG TABLET_201145_1
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Spnib 70mg Tablet

Prescription Required

Salt Composition : Dasatinib

Manufacturer : ZYDUS CADILA

Origin of Medicine : India

MRP: ₹4390
Price : ₹3731
You Save : ₹659 (15%)

60 Tablet(s) In A Bottle

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Introduction to Spnib 70mg Tablet

Spnib 70mg tablet consists of the active ingredient Dasatinib. It is prescribed for adults and children above one year of age with Chronic Myeloid Leukemia. This medicine is used to treat newly diagnosed Philadelphia chromosome-positive (Ph+) chronic myeloid leukemia (CML) in the chronic phase and Ph+ acute lymphoblastic leukemia in patients resistant to other therapies. Chronic Myeloid Leukemia refers to a type of blood cancer that makes the body produce too many white blood cells that happen due to alteration in the Philadelphia chromosome. Acute Lymphoblastic Leukemia is the most common form of blood cancer that affects children. In this case, the lymphocytes of white blood cells multiply too quickly and live too long.

 

The common side effects that are likely to be associated with the Spnib 70mg tablet are diarrhea, headache, cough, rash, nausea, tiredness, vomiting, muscle pain, weakness, low appetite, and high or low blood pressure. Inform your doctor if these side effects disturb or persist.

 

Inform your doctor if you are allergic to Spnib 70mg and its ingredients. Before starting treatment with this medication, you should let your physician know if you have liver or heart problems, breathing difficulties, chest pain, cough, hepatitis B infection, or bleeding problems. This medicine could cause a severe reduction in the number of platelets, WBC or RBC in the blood. Ensure that your physician monitors your blood levels at regular intervals. Tell your healthcare professional about all the medicines you take, including prescription and over-the-counter medicines, vitamins, antacids, and herbal supplements. It is not recommended for children below one year of age.

Uses of Spnib 70mg Tablet

Spnib 70mg tablet is indicated for the following conditions:

  • Children and adults with chronic myeloid leukemia.
  • Adults with Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL) with resistance to prior therapy.

Therapeutic Effects of Spnib 70mg Tablet

Spnib 70mg tablet works by preventing the abnormal protein from signaling the growth of cancer cells. This aids in preventing or reducing the spread of cancer cells.

Interaction of Spnib 70mg Tablet with other drugs

Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional or vitamin supplements, and herbal products that you are taking or have taken before the treatment. Certain medications may interact with Spnib 70mg tablet and can cause undesirable side effects. 

More Information about Spnib 70mg Tablet

Store protected from light at a temperature not exceeding 30c.

How to consume Spnib 70mg Tablet

Take the tablet with or without food at the same time each day. Do not break, crush or chew the tablet. Your doctor will decide the dose and frequency of administration of Spnib 70mg tablet based on your disease severity and other factors. Do not stop taking the tablet without consulting your healthcare professional. 

Safety Advices for Spnib 70mg Tablet

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Pregnancy

  

Spnib 70mg tablet is not recommended to use during pregnancy unless clearly necessary. Your physician will discuss the potential risk during pregnancy. Women should use effective birth control during treatment and 30 days after the final dose. 

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Breast Feeding

  

It is not recommended to breastfeed while taking Spnib 70mg tablet as it is not known whether this medication passes into breast milk. You should not breastfeed during treatment and for 2 weeks after your final dose.

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Lungs

  

It is unknown whether Spnib 70mg is safe to administer in patients with lung problems. Inform your physician if you have any lung disease before starting the treatment.

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Liver

  

Inform your physician before starting this treatment if you have liver diseases. Your physician will prescribe a dose accordingly.

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Alcohol

  

It is not known whether it is safe to consume alcohol with Spnib 70mg tablet. Consult your doctor for advice.

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Driving

  

Avoid driving or using machinery if you experience symptoms like breathlessness or altered consciousness. 

Side Effects of Spnib 70mg Tablet

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. 

Serious

  • Unusual bleeding or bruising
  • Rapid heart rate
  • Changes in consciousness or speech
  • Breathlessness and swelling all over the body
  • Fever or signs of infection
  • Fluid retention
  • Heart problems
  • Myelosuppression
  • Severe allergic reaction

Common

  • Diarrhea
  • Headache
  • Cough
  • Rash
  • Nausea, tiredness, vomiting
  • Muscle pain, weakness
  • Low appetite
  • High or low BP

Word of Advice

It is advised to use effective contraceptives for both men and women taking Spnib 70mg tablet during treatment and 30 days after the last dose. Monitor your blood pressure regularly while taking this medication. Inform your doctor if you notice blood in your urine or stools. If you take an antacid medicine, take it 2 hours before or 2 hours after taking this tablet. 

FAQs

Q 1. Can children use Spnib 70mg tablet?

Spnib 70mg tablet is not recommended for children under the age of one.

Q 2. Can Spnib 70mg tablet cause hair loss?

Yes, Hair loss is one of the common side effects of taking Spnib 70mg. Consult your doctor for advice if this side effects disturbs or persists you.

Q 3. Is Spnib 70mg tablet a chemotherapy drug?

Yes, Spnib 70mg tablet is a chemotherapy medication that belongs to the group of Tyrosine kinase inhibitor.

Q 4. Spnib 70mg tablet be taken with food?

Yes, Spnib 70mg tablet can be taken with or without food. Do not take this medication with grapefruit and its juices.

Q 5. Who is contraindicated to take Spnib 70mg tablet?

Spnib 70mg tablet is contraindicated for pregnant and breastfeeding women and children whose ages below one year. It is not recommended if you are allergic to Dasatinib and its ingredients.

Fact Box of Spnib 70mg Tablet

Molecule Name: Dasatinib

 

Therapeutic class: Anti-neoplastics
Pharmacological class: Tyrosine kinase inhibitor

Indications: 

1. Myeloid leukemia 

2. Philadelphia chromosome-positive acute lymphoblastic leukemia 

References

  1. Bristol-Myers Squibb Pharma, Electronic Medicines Compendium (EMC), [Revised on Mar 2022] [Accessed on 1st Dec 2022], https://www.medicines.org.uk/emc/files/pil.7745.pdf
  2. Bristol-Myers Squibb Company, [Revised on Jun 2021] [Accessed on 1st Dec 2022], https://packageinserts.bms.com/ppi/ppi_sprycel.pdf
  3. H.G. Watson, J.I.O. Craig, L.M. Manson, Blood disease, Davidson’s Principles and Practice of Medicine, 22nd Edition, 2014, 989-1056.
  4. Edward Chu, Cancer Chemotherapy, Lange’s Basic and Clinical Pharmacology, 14th Edition, 2018, 948-976.

Disclaimer

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