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Stamaril Injection
Prescription Required
Salt Composition : Yellow Fever Vaccine
Manufacturer : SANOFI AVENTIS
Origin of Medicine : France
1 Prefilled Syringe(s)
Introduction to Stamaril Injection
Stamaril injection contains active components as Yellow fever vaccine. It is a crucial immunization that protects against the yellow fever virus. Yellow fever is a viral disease transmitted to humans through the bite of infected mosquitoes, primarily the Aedes aegypti mosquito. The primary benefit of this vaccine is its ability to prevent the potentially life-threatening disease caused by the yellow fever virus. Vaccinated individuals are far less likely to contract yellow fever when exposed to the virus. When a significant portion of the population is immune to the virus, it reduces the overall risk of transmission, protecting vulnerable individuals who cannot receive the vaccine due to medical reasons. A single dose of this vaccine typically provides long-lasting immunity for many years, often for a lifetime. The vaccine helps reduce the burden on healthcare systems by preventing yellow fever cases.
If an individual has previously experienced a severe allergic reaction (anaphylaxis) to any component of the Stamaril injection, such as eggs or gelatin, they should not receive the vaccine. People with weakened immune systems due to conditions like HIV/AIDS, certain cancers, or immunosuppressive medications (e.g., high-dose steroids, chemotherapy) should generally not receive this vaccine. Individuals with severe thymus disorders like DiGeorge syndrome should avoid the vaccine. If an individual has had their thymus gland removed, they are typically advised not to receive this vaccine. Older adults can receive the vaccine if they are in good health and meet the other eligibility criteria. People allergic to Sorbital should not take this medicine. This Stamaril injection is not recommended for infants under 6 months of age.Â
Uses of Stamaril Injection
Stamaril injection is used for the following:
- Prevent yellow fever
- Travel health
- Epidemic control
- Laboratory workers
- Occupational risk
Therapeutic Effects of Stamaril Injection
The Stamaril injection functions by introducing a weakened form of the yellow fever virus into the body. This weakened virus triggers an immune response, teaching the immune system to recognize and defend against the virus. In the event of future exposure to the virus, the immune system is prepared to swiftly and effectively combat it, protecting against yellow fever.
Interaction of Stamaril Injection with other drugs
Inform the doctor about your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with the Stamaril injection, reducing effectiveness by causing undesirable side effects.Â
More Information about Stamaril Injection
- Stored at room temperature from 2°C to 8°C
- Keep away from moisture, heat, and light.
- It should not be frozen.
- Keep away from children and pets.
How to consume Stamaril Injection
The Stamaril injection is typically administered via a single subcutaneous (under the skin) injection. This administration route allows the vaccine to enter the bloodstream and stimulate the immune system to develop protection against the yellow fever virus. It is a standard practice to administer the vaccine just under the skin, usually in the upper arm.
Safety Advices for Stamaril Injection
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Pregnancy
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Consult your doctor before using Stamaril injection if you are pregnant or planning to become pregnant.
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Breast Feeding
 ÂConsult your doctor before using Stamaril injection if you are breastfeeding women. They will assess your condition individually.
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Lungs
  Stamaril injection is generally not associated with adverse effects on lung health. However, consult your healthcare provider for specific concerns or lung conditions.
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Liver
  Individuals with mild liver conditions can usually receive the Stamaril injection safely. However, those with severe liver disease should consult their healthcare provider for an individual risk assessment.
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Alcohol
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It is generally not safe to take alcohol with the Stamaril injection as excessive alcohol intake can weaken the immune response.
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Driving
  The Stamaril injection is not known to impair one's ability to drive, so it is typically safe to operate a vehicle after vaccination. However, some individuals may experience mild side effects, such as fatigue or dizziness, so it's advisable to consult a healthcare professional.
Side Effects of Stamaril Injection
The Stamaril injection causes some side effects like all medications, although not everyone will experience them.Â
Serious
- Respiratory depression
- Cardiovascular effects
- Malignant hyperthermia
- Allergic reactions
- Liver and kidney function changes
- Neurological effects
Common
- Nausea and vomiting
- Headache
- Sore throat and cough
- Shivering
- Confusion or memory changes
Word of Advice
Individuals planning to receive the Stamaril injection should consult a healthcare provider experienced in travel medicine for personalized guidance. Precautions include assessing overall health, discussing medical history and medications, considering potential allergies, verifying vaccine availability, adhering to recommended timing, and obtaining an International Certificate of Vaccination. Special attention is warranted for pregnant and breastfeeding individuals, those with weakened immune systems, and individuals with severe allergies. While traveling, it is vital to stay informed about regional vaccination requirements, potential outbreaks, and emergency medical care options.Â
FAQs
Q 1. When should I get the Stamaril injection before traveling?
You should receive the vaccine at least ten days before your planned travel to a yellow fever-endemic area. This allows your body to develop immunity before potential exposure.
Q 2. How long does the protection from the Stamaril injection last?
In many cases, a single dose of the Stamaril injection provides long-lasting immunity, often for a lifetime. However, some individuals may require booster doses after ten years if they are still at risk of exposure.
Q 3. Can I receive the Stamaril injection during a yellow fever outbreak in my destination?
During outbreaks, vaccination recommendations may change. Consult with healthcare providers and local health authorities for guidance on whether to proceed with your travel plans and vaccination
Q 4. What should I do if I develop symptoms such as fever or rash after receiving the Stamaril injection?
Mild side effects like fever, headache, and muscle aches can occur but usually resolve independently. However, seek medical attention promptly if you experience severe or unusual symptoms.
Q 5. Is receiving the Stamaril injection safe if I have a history of a severe mosquito-borne disease, such as dengue fever?
A history of other mosquito-borne diseases is generally not a contraindication for the Stamaril injection. Consult with a healthcare provider for personalized advice.
Q 6. Is there a risk of transmitting the vaccine virus to others, such as through close contact or sexual activity?
The risk of transmitting the vaccine virus to others through close contact or sexual activity is exceedingly low and not a significant concern.
Fact Box of Stamaril Injection
Molecule name:Â Â Yellow fever vaccine | Therapeutic class: Immunization Agent |
Pharmacological class: Viral Vaccine | Indications:  1. Prevent yellow fever 2. Travel health 3. Epidemic control 4. Laboratory workers 5. Occupational risk |
References
- Sanofi Pasteur Europe, Electronic Medicines Compendium (EMC), [Revised on 15 Feb 2021] [Accessed on 5th September 2023], https://www.medicines.org.uk/emc/product/1683/smpc#grefÂ
- D.H. Dockrell, S. Sundar, B.J. Angus, R.P. Hobson, Infectious disease, Davidson’s Principles and Practice of Medicine, 22nd Edition, 2014, 293-386.
- Sanofi Pasteur Inc. US Food and Drug Administration, [Revised on February 2019.] [Accessed on 5th September 2023], https://www.fda.gov/media/76015/download#:~:text=YF-VAX®%2C%20Yellow%20Fever,is%20hermetically%20sealed%20under%20nitrogen.
- Roberto Tinoco and James E. Crowe, Jr., Immune Globulins and Vaccines, Goodman & Gilman's The Pharmacological Basis of Therapeutics, 13th Edition, 2018, 655-672.
Disclaimer
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