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Tazid 250mg Injection
Prescription Required
Salt Composition : Ceftazidime
Manufacturer : ALKEM LABORATORIES LTD
Origin of Medicine : India
1 Vial(s)
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Introduction to Tazid 250mg Injection
Tazid 250mg Injection contains an active component as Ceftazidime. It is an antibiotic medication that belongs to the class of drugs known as cephalosporins. This medication has a broad spectrum of activity against Gram-negative bacteria, including Pseudomonas aeruginosa, Klebsiella species, Escherichia coli, Proteus species, and many others. It is commonly used to treat various bacterial infections caused by susceptible organisms. It is used in treating lower respiratory tract infections, skin and skin structure infections, bone and joint infections, urinary tract infections, gynecologic infections, bacterial septicemia (bacterial infection entering the bloodstream), abdominal infections, and central nervous system infections caused by various strains of bacteria. This medicine can be combined with other antibiotics to create synergistic effects, enhancing the overall effectiveness of treatment in certain cases.
Individuals with a known allergy to cephalosporin antibiotics or penicillin antibiotics may have an increased risk of allergic reactions to Tazid 250mg Injection. It is primarily excreted through the kidneys. Patients with impaired kidney function may require dose adjustments or close monitoring to avoid potential side effects or toxicity. This can sometimes cause gastrointestinal disturbances such as diarrhea, colitis, or pseudomembranous colitis. Patients with a history of gastrointestinal diseases should be monitored closely while taking this medication. Some formulations of Tazid 250mg Injection may contain ingredients not recommended for use in newborns and infants. Always check with a pediatrician before administering any medication to young children.
Uses of Tazid 250mg Injection
Tazid 250mg Injection is used to treat the following:
- Respiratory tract infections
- Urinary tract infections
- Bone and joint infections
- Gynecologic infections
- Skin infections
- Abdominal infections
- Bacterial septicemia
- Infections in the nervous system
Therapeutic Effects of Tazid 250mg Injection
The therapeutic effect of Tazid 250mg Injection is its ability to effectively treat a wide range of serious bacterial infections, particularly those caused by Gram-negative bacteria. As a potent and broad-spectrum cephalosporin antibiotic, this medication works by inhibiting bacterial cell wall synthesis, leading to the destruction of susceptible bacteria. Its bactericidal action makes it a crucial choice in combating infections like complicated intra-abdominal infections, hospital-acquired pneumonia, bloodstream infections, urinary tract infections, and certain skin and soft tissue infections. Its intravenous formulation allows for rapid delivery and steady blood levels, making it well-suited for severe infections requiring immediate treatment.Â
Interaction of Tazid 250mg Injection with other drugs
Inform the doctor about your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Tazid 250mg Injection, reducing effectiveness by causing undesirable side effects.Â
More Information about Tazid 250mg Injection
- Store at room temperature, between 20°C to 25°C (68°F to 77°F).
- Keep away from moisture, heat, and light.
- It should not be frozen.
- Keep away from children and pets.
How to consume Tazid 250mg Injection
Tazid 250mg Injection is typically administered via injections in hospital settings by a healthcare professional. The dosage and frequency of administration depend on the severity of the infection, the patient's age, and kidney function.
Safety Advices for Tazid 250mg Injection
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Pregnancy
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Pregnant women should inform their healthcare provider about their pregnancy status before starting treatment with Tazid 250mg Injection. The healthcare provider will carefully consider the specific circumstances and the severity of the infection before deciding to use this antibiotic during pregnancy.
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Breast Feeding
 ÂTazid 250mg Injection can pass into breast milk, but the amount transferred is usually considered low. It is generally considered safe to use this medication while breastfeeding, especially in short courses or single doses. However, as a precaution, it is advisable to consult a healthcare professional before using this medication while breastfeeding.Â
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Lungs
  Patients with lung infections or other respiratory conditions should consult their healthcare providers to ensure the appropriate use of Tazid 250mg Injection or any other medication.Â
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Liver
  If you have liver-related medical conditions, such as liver disease or liver dysfunction, it is crucial to inform your healthcare provider about your condition before starting Tazid 250mg Injection or any other medication.Â
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Alcohol
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There is no direct interaction between Tazid 250mg Injection and alcohol. However, it's always advisable to avoid excessive alcohol consumption while on any medication, as alcohol can interfere with the body's ability to metabolize drugs, potentially leading to increased side effects or reduced medication efficacy.
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Driving
  Tazid 250mg Injection is not known to cause drowsiness or impair cognitive functions that could significantly affect driving ability.Â
Side Effects of Tazid 250mg Injection
Tazid 250mg Injection causes some side effects like all medications, although not everyone will experience them.Â
Serious:
- Severe allergic reactions
- Severe skin reactions
- Clostridium difficile-associated diarrhea
- Liver problems (jaundice, dark urine, and persistent abdominal pain)
- Decreased urine output
- Swelling in the legs or ankles
- Changes in urination frequency
Common:
- Nausea
- Vomiting
- Diarrhea
- Rash
- Itching
- Pain or inflammation at the injection site (for intravenous use)
- Headache
- Fever
Word of Advice
Patients with a history of allergies to cephalosporin or penicillin antibiotics should inform their healthcare provider to avoid potential allergic reactions. It is essential to complete the full course of treatment as prescribed, even if symptoms improve, to prevent antibiotic resistance. Tazid 250mg Injection can disrupt normal gut flora, leading to Clostridium difficile-associated diarrhea, so any signs of persistent diarrhea should be reported to the healthcare provider. Patients with impaired kidney or liver function may require dose adjustments or close monitoring.Â
Since this medication can affect electrolyte levels, careful monitoring may be necessary, especially in high-risk patients. Use during pregnancy and breastfeeding requires careful evaluation by a healthcare professional to balance potential risks and benefits. Caution should be exercised in patients with central venous catheters to prevent catheter-related infections. Patients should promptly report any unusual or severe side effects to their healthcare provider.
FAQs
Q 1. What should I do if I miss a dose of Tazid 250mg Injection?
If you miss a dose of Tazid 250mg Injection, contact your healthcare provider or nurse immediately to determine the appropriate course of action. It may be necessary to administer the missed dose as soon as possible or adjust the dosing schedule to maintain the effectiveness of the medication.
Q 2. Can I stop taking Tazid 250mg Injection if I feel better?
No, it's essential to complete the full course of Tazid 250mg Injection as prescribed by your healthcare provider, even if you start feeling better. Stopping the medication prematurely could lead to incomplete eradication of the infection and potential development of antibiotic resistance. Always follow the full treatment duration to ensure effective results.
Q 3. Can Tazid 250mg Injection cause birth control pills to be less effective?
Tazid 250mg Injection does not directly interfere with the efficacy of hormonal birth control methods like pills, patches, or injections. However, it's always a good idea to discuss any concerns with your healthcare provider, who can provide more personalized advice on contraceptive methods and potential interactions.
Q 4. How long does it take for Tazid 250mg Injection to start working?
The time it takes for Tazid 250mg Injection to start working varies depending on the individual's infection and response to the medication. Some patients may experience symptom improvement within a few days of starting treatment, while others may take longer.
Q 5. Can Tazid 250mg Injection be used for children or elderly patients?
Tazid 250mg Injection can be used in both pediatric and elderly patients. However, dosages may need adjustment based on the patient's age, weight, kidney function, and other medical conditions. Pediatric and geriatric patients may require more frequent monitoring during treatment.
Q 6. What should I do if I experience severe or persistent side effects while taking Tazid 250mg Injection?
If you experience severe or persistent side effects while taking Tazid 250mg Injection, such as difficulty breathing, severe rash, or persistent diarrhea, seek immediate medical attention.
Fact Box of Tazid 250mg Injection
Molecule name: Ceftazidime | Therapeutic class: Antibiotic |
Pharmacological class: Cephalosporins
| Indications:Â 1. Respiratory tract infections 2. Urinary tract infections 3. Bone and joint infections 4. Gynecologic infections 5. Skin infections 6. Abdominal infections 7. Bacterial septicemia 8. Infections in the nervous system |
References
- KD Tripathi, Essentials of Medical Pharmacology, Beta-Lactam Antibiotics, 7th edition, 2013,728.
- Goodman & Gilman’s, The Pharmacological Basics of Therapeutics, Penicillins, Cephalosporins and other Beta-Lactam Antibiotics, 12th edition, 2011, 1498.
- B. Braun Medical Inc., US Food and Drug Administration, [Revised on October 2021] [ Accessed on 21st July 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/050823s009lbl.pdf.
- Wockhardt UK Ltd, Electronic medicines compendium (EMC), [Revised on 16 Aug 2021] [ Accessed on 21st July 2023], https://www.medicines.org.uk/emc/files/pil.6346.pdfÂ
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