All Substitutes
Loading...
Disclaimer
Did you find this information helpful?
  Â
Tenectase 20mg Injection
Prescription Required
Salt Composition : Tenecteplase
Manufacturer : GENNOVA BIOPHARMACEUTICALS LTD
Origin of Medicine : India
1 Kit
Introduction to Tenectase 20mg Injection
Tenectase 20mg Injection belongs to the antiplatelet agent category, containing the active ingredient Tenecteplase. It is used to prevent blood clots in patients with acute coronary syndrome (ACS), including unstable angina or myocardial infarction (heart attack).
This drug is contraindicated in individuals with known hypersensitivity or allergic reactions to other ingredients in it. If you are scheduled for surgery (including dental work), it is important to inform your doctor. Due to the increased risk of bleeding associated with Tenectase 20mg Injection, your physician may advise you to stop taking the medication five days prior to the surgery. If you develop irregular breathing patterns such as speeding up, slowing down, or experiencing short pauses in breathing, it is recommended to consult your doctor for further evaluation.
Tenectase 20mg Injection is not recommended during pregnancy or if there is a possibility of becoming pregnant. It is advised for women to use appropriate contraceptive measures to prevent pregnancy while using this medication. If you are breastfeeding, it's important to consult with your physician before taking this drug.
Uses of Tenectase 20mg Injection
- Prevent blood clots in patients with acute coronary syndrome (ACS)
Therapeutic Effects of Tenectase 20mg Injection
Tenectase 20mg Injection works by inhibiting platelet activation and aggregation. It specifically blocks a receptor called P2Y12 on the platelets, preventing them from clumping together and forming blood clots. This helps reduce the risk of heart-related events in individuals with ACS.
Interaction of Tenectase 20mg Injection with other drugs
Inform your physician about all your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications such as rosuvastatin, rifampicin, phenytoin, digoxin, cyclosporine, verapamil and opioids may interact with Tenectase 20mg Injection and reduce effectiveness by causing undesirable side effects.
More Information about Tenectase 20mg Injection
- Do not store Tenectase 20mg Injection above (30°C).
- Keep out of reach of children.
How to consume Tenectase 20mg Injection
Tenectase 20mg Injection can be administered only as an intravenous injection into a vein by your physician in a hospital setting. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition.Â
Safety Advices for Tenectase 20mg Injection
 Â
Pregnancy
 Â
Tenectase 20mg Injection is not recommended during pregnancy or if there is a possibility of becoming pregnant. It is advised for women to use appropriate contraceptive measures to prevent pregnancy while using this medication.
 Â
Breast Feeding
 Â
If you are breastfeeding, it's important to consult with your physician before taking Tenectase 20mg Injection.
 Â
Lungs
  Inform your doctor if you have lung disease because the Tenectase 20mg Injection should be used cautiously with a lung condition.
 Â
Liver
  It is unknown whether Tenectase 20mg Injection is safe for patients with liver problems. Inform your physician if you have liver disease before starting the treatment.Â
 Â
Alcohol
 ÂIt is unknown whether consuming alcohol interacts with Tenectase 20mg Injection. Please consult your doctor for more advice.
 Â
Driving
 Â
Tenectase 20mg Injection are not known to cause drowsiness or impair driving ability, so they are generally considered safe for use while driving or operating machinery.
Side Effects of Tenectase 20mg Injection
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Serious
- Shortness of breath
- Blood clotting problem called TTP (purplish spots in the mouth or mouth, fever, confusion, yellowing of the eyes or skin, fever)
- Fainting
- Bleeding (red or black stools, coughing up or vomiting with blood, red, pink, or brown urine)
Common
- Headache
- Indigestion
- Nausea
- Constipation
- Rash, itching
- Pain and swelling in the joints
- Blurred vision
- Bleeding gums
- Bruising
Word of Advice
Since Tenectase 20mg Injection affects platelet production, it's essential to take precautions to avoid injuries and bleeding. Be cautious when engaging in activities that may increase your risk of injury, and report any unusual bleeding or bruising to your physician.
FAQs
Q 1. How does Tenectase 20mg Injection work?
Tenectase 20mg Injection works by inhibiting platelet activation and aggregation. It specifically blocks a receptor called P2Y12 on platelets, which prevents them from sticking together and forming blood clots. This helps maintain blood flow and reduce the risk of cardiovascular events in patients with ACS.
Q 2. How is Tenectase 20mg Injection taken?
Tenectase 20mg Injection can be administered only as an intravenous injection into a vein by your physician in a hospital setting. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition
Q 3. What are the common side effects of Tenectase 20mg Injection?
Common side effects of Tenectase 20mg Injection may include bleeding, shortness of breath, headache, dizziness, nausea, and fatigue. It is important to seek medical attention if you experience any signs of bleeding, such as prolonged or excessive bleeding from cuts, blood in urine or stool, or unexplained bruising.
Q 4. Are there any drug interactions with Tenectase 20mg Injection?
Tenectase 20mg Injection may interact with other medications, including prescription drugs, over-the-counter medications, and herbal supplements. It is crucial to inform your healthcare provider about all the medications you are taking to avoid potential interactions that may affect the safety or efficacy of this drug.
Q 5. What should I do if I miss a dose of Tenectase 20mg Injection?
If you miss a dose of Tenectase 20mg Injection, take it as soon as you remember and then continue with your regular dosing schedule. Do not take a double dose to make up for a missed dose unless advised by your healthcare provider.
Fact Box of Tenectase 20mg Injection
Molecule name: Tenecteplase | Therapeutic class: Thrombolytics |
Pharmacological class: Tissue-plasminogen activator (tPA) | Indications: Prevent blood clots |
References
- Boehringer Ingelheim Ltd, Electronic medicines compendium (EMC), [ Revised on Feb 2023] [ Accessed on 18th July 2023], https://www.medicines.org.uk/emc/files/pil.3013.pdf
- Genentech, Inc, US Food and Drug Administration, [ Revised on Feb 2018] [ Accessed on 18th July 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/103909s5187lbl.pdf
- Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Modulation of cardiovascular functions, 12th edition, 2011, 866.
- KD Tripathi, Essentials of Medical Pharmacology, Drugs affecting coagulation, bleeding and thrombosis, 7th edition, 2013, 627.
Disclaimer
MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.
