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  ÂTerifrac PEN Injection
Prescription Required
Salt Composition : Pen Device
Manufacturer : INTAS PHARMACEUTICALS LTD
Origin of Medicine : India
1 Pen Device(s)
Introduction to Terifrac Pen Injection
Terifrac Pen injection contains the active component of Teriparatide, which is a synthetic version of parathyroid hormone (PTH). It is used to reduce osteoporosis in both men and postmenopausal women. Osteoporosis is a condition that weakens bones and increases the risk of fractures. This medicine works by promoting the creation of new bone tissue, enhancing bone mineral density, and accelerating bone healing.Â
Do not take Terifrac pen injection if you are allergic to Teriparatide or its ingredients. Do not take this medicine if you have elevated calcium levels (pre-existing hypercalcemia), serious kidney issues, bone cancer or metastatic cancer to bones, specific bone diseases, unexplained high alkaline phosphatase levels in the blood, or a history of bone-related radiation therapy. Before starting the treatment with Terifrac pen injection, notify your doctor if you experience persistent nausea, vomiting, constipation, low energy, or muscle weakness, which could indicate elevated blood calcium levels. If you have a history of kidney stones or any kidney issues, it's crucial to inform your healthcare provider. This medicine is not recommended for use in children or adolescents under 18 years and in growing adults.Â
Uses of Terifrac Pen Injection
- Used to reduce osteoporosis in men and postmenopausal women.Â
Therapeutic Effects of Terifrac Pen Injection
Terifrac Pen injection stimulates new bone tissue formation and increases mineral density by activating bone-forming osteoblasts. This process strengthens bones, reduces fracture risk, and promotes healing.
Interaction of Terifrac Pen Injection with other drugs
Inform the doctor about your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with the Terifrac Pen injection, reducing effectiveness by causing undesirable side effects.Â
More Information about Terifrac Pen Injection
- Stored at controlled room temperature, between 2°C to 8°C.
- Keep away from moisture, heat, and light.
- It should not be frozen.
- Keep away from children and pets.
How to consume Terifrac Pen Injection
Terifrac Pen injection is typically administered by a healthcare professional. It is usually given as an injection. It is usually administered subcutaneously in the thighs or in the abdomen. Your doctor will decide the dose, route of administration, and frequency based on your disease condition and other factors.Â
Safety Advices for Terifrac Pen Injection
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Pregnancy
 ÂIt is unsafe to use Terifrac Pen injection during pregnancy. Before starting the treatment, inform your doctor if you are pregnant, planning to get pregnant, or think you may be pregnant.Â
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Breast Feeding
 ÂIt is unsafe to use Terifrac Pen injection during breastfeeding. So, before starting the treatment, inform your doctor if you are breastfeeding. Contact your doctor for more information.Â
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Lungs
 ÂIt is unknown whether Terifrac Pen injection is safe for patients with lung problems. Inform your physician if you have any lung disease before starting the treatment. Contact your doctor if you experience any lung-related symptoms.
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Liver
 ÂWhether Terifrac Pen injection is safe for patients with liver problems is unknown. Inform your physician if you have any liver disease before starting the treatment. Contact your doctor if you experience any liver-related symptoms.
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Alcohol
 ÂAvoid consuming alcohol while taking the Terifrac Pen injection. Alcohol can impair the body's immune system, making it less effective in fighting infections. Contact your doctor for more information.Â
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Driving
 ÂIt is unsafe to drive while taking this medicine. People may experience side effects, including dizziness, drowsiness, or fatigue, after using Terifrac Pen injection. In that case, avoid driving or operating heavy machinery.
Side Effects of Terifrac Pen Injection
Terifrac Pen injection causes some side effects like all medications, although not everyone will experience them.Â
Serious
- Hypercalcemia
- Allergic reactions that affect skin and breathing.
- Skin reactions such as rashes, bruising, swelling, and itching at the site of injection.
Common
- Arthralgia
- Nerve Pain
- Nausea
- Sickness
- Headache
- Dizziness
- Increased sweating
- Breathlessness
- Muscle cramps
- Increase in blood cholesterol levels.
- Chest pain
- Burning sensation below the breastbone
- Anaemia
Word of Advice
Notify your doctor if you experience any serious side effects. Your medical professional will inform you if you need any dose adjustments. Contact your doctor for more information. Regular monitoring of serum calcium levels is essential to identify and manage hypercalcemia. In patients with orthostatic hypotension or pre-existing hyperparathyroidism, Terifrac Pen injection should be used cautiously. The duration of treatment with this medication is generally limited, and its use is not advised in pediatric patients.
FAQs
Q 1. Can I use Terifrac Pen injection with other medications?
Before using this medicine, it is essential to consult your doctor, as they can interact with various other medications. Getting suggestions from your doctor will help ensure the safe and appropriate use of Terifrac Pen injection with your current medication regimen.
Q 2. Can Terifrac Pen injection be used in individuals with a history of cancer?
Terifrac Pen injection is generally not recommended for individuals with a history of cancer, especially skeletal malignancies or bone metastases. The medication has been associated with an increased risk of osteosarcoma, and its safety in individuals with a history of cancer has not been well established.
Q 3. Is it okay to consume alcohol while taking Terifrac Pen injection?
Do not consume alcohol while taking Terifrac Pen injection because alcohol can impair the body's immune system, making it less effective in fighting infections. Contact your doctor for more information.
Q 4. Can Terifrac Pen injection be used in men with osteoporosis?
Yes, Terifrac Pen injection can be used in men with osteoporosis. While osteoporosis is more commonly associated with women, men can also develop the condition. It can effectively increase bone density and reduce fracture risk in men with osteoporosis.
Q 5. What are the side effects of Terifrac Pen injection?
Terifrac Pen injection may cause side effects, including common ones such as injection site reactions, nausea, dizziness, and headache. Serious side effects, though rare, can include the development of osteosarcoma, a type of bone cancer, and the potential for hypercalcemia, which can lead to symptoms like excessive thirst and muscle weakness.
Fact Box of Terifrac Pen Injection
Molecule name: Terifrac Pen injection  | Therapeutic class: Bone formation stimulator |
Pharmacological class: Parathyroid hormone analogs | Indications: Used to reduce osteoporosis in men and postmenopausal women. |
References
- Eli Lilly and Company Limited, Electronic medicines compendium (EMC), [Revised on April 2023], [Accessed on 11th August 2023], https://www.medicines.org.uk/emc/files/pil.3634.pdf
- Eli Lilly and Company, US Food and Drug Administration, [Revised on September 2021],[Accessed on 11th August 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/021318Orig1s056lbl.pdf
- KD Tripathi, Hormones and Drugs Affecting Calcium Balance, Essentials of Medical Pharmacology, 8th Edition, 2019, 360-372
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