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Trombopag 50mg Tablet
Prescription Required
Salt Composition : Eltrombopag
Manufacturer : NATCO PHARMA LTD
Origin of Medicine : India
7 Tablet(s) In A Strip
Introduction to Trombopag 50mg Tablet
Trombopag 50mg tablet is an anticoagulant drug belonging to the thrombopoietin (TPO) receptor agonist category, containing the active ingredient Eltrombopag. It treats low platelet counts caused by primary immune thrombocytopenia (ITP) or hepatitis C (HCV) infection. ITP refers to an autoimmune disorder in which the immune system destroys platelets. Platelets are blood cells that aid in clotting and protect blood vessel walls. When platelet levels are low, it can result in severe bleeding and bruising. This tablet is also used in adults to treat low blood counts caused by severe aplastic anaemia (a serious blood disease that occurs when the bone marrow fails to produce enough new blood cells).
This drug should not be used in individuals with known hypersensitivity or allergic reactions to the drug or its components. Allergic reactions can range from mild to severe and may include symptoms such as rash, itching, swelling, dizziness, or difficulty breathing. Trombopag 50mg tablet are contraindicated in patients with severe liver impairment or active liver disease. This drug can potentially cause hepatotoxicity, as increased liver enzymes and bilirubin levels indicate. Using this drug in individuals with severe liver disease can further worsen liver function, so caution is advised. Your doctor will recommend that you are checked for cataracts. Your doctor should arrange regular testing if you do not have routine eye tests. You may also be checked for bleeding in or around your retina (the light-sensitive layer of cells at the back of the eye).
If you stop taking this tablet, your blood platelet count is likely to become low again within several days. The platelet count will be monitored, and your doctor will discuss appropriate precautions. A very high blood platelet count may increase the risk of blood clotting. However, blood clots can also form with normal or even low platelet counts. Your doctor will adjust your dose of this medicine to ensure that your platelet count does not become too high. Do not take this tablet with dairy products or drinks, as the calcium in these items affects the absorption of the medicine. Use effective birth control during the treatment, and if you become pregnant, you must inform your doctor. Trombopag 50mg tablet are not advised for children under one with ITP. It is also not recommended for patients under 18 with low platelet counts caused by hepatitis C or severe aplastic anaemia. Tell your doctor if you are taking, have recently taken, or might take other medicines. It includes medicines obtained without a prescription and vitamins.
Uses of Trombopag 50mg Tablet
Trombopag 50mg tablet is used to treat,
- Low platelet counts are caused by primary immune thrombocytopenia (ITP) or hepatitis C virus (HCV) infection.
- Severe aplastic anemia.
Therapeutic Effects of Trombopag 50mg Tablet
Trombopag 50mg tablet stimulates megakaryocytes (the large bone marrow cells) responsible for producing platelets. By raising the number of platelets in the blood, this drug prevents bleeding and bruising.
Interaction of Trombopag 50mg Tablet with other drugs
Inform your healthcare provider about your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications include antacid medicines, statins, ciclosporin, methotrexate, topotecan, lopinavir, or ritonavir, and vitamin and mineral supplements may interact with Trombopag 50mg tablet and reduce effectiveness by causing undesirable side effects
More Information about Trombopag 50mg Tablet
- Store Trombopag 50mg tablet at room temperature (25°C).
- Keep the medicine out of reach of children and pets.
How to consume Trombopag 50mg Tablet
It is an orally available prescription drug. Your doctor will decide the dose and duration of the drug based on the disease condition and other factors. Always take an Trombopag 50mg tablet as prescribed by your doctor. Take the tablet with or without food. Do not chew, crush, or break the tablet. Swallow the whole tablet with water.
Safety Advices for Trombopag 50mg Tablet
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Pregnancy
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Trombopag 50mg tablet is not recommended for pregnant patients because it may cause fetal harm. You must inform your doctor if you are pregnant, suspecting, or planning to get pregnant during the treatment.
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Breast Feeding
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It is not known whether Trombopag 50mg tablet passes into breast milk. If you are breastfeeding or planning to breastfeed, tell your doctor.
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Lungs
  It is unknown whether Trombopag 50mg tablet can be prescribed for patients with lung problems. Consult your doctor if you have any lung diseases before starting the treatment.
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Liver
  Trombopag 50mg tablet should be cautiously administered in patients with severe liver diseases. Dose adjustments are necessary for severe liver failure. Inform your doctor if you have liver issues before initiating the therapy.
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Alcohol
 ÂIt is unknown whether alcohol may interact with the Trombopag 50mg tablet. Inform your physician if you drink alcoholic beverages.
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Driving
  Driving vehicles or operating heavy machinery is unsafe after taking the Trombopag 50mg tablet. It may cause dizziness and impair concentration.
Side Effects of Trombopag 50mg Tablet
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Common
- Nausea
- Diarrhea, abdominal pain
- Common cold
- Cough
- Respiratory tract infection
- Back pain
- High temperature, cough
- Loss of appetite
- Hair loss
- Swelling in feet or hands
- Headache, dizziness
- Mouth and throat pain
- Joint pain
Word of Advice
Ensure that in the 2 hours after or 4 hours before you take this medication, you don’t consume dairy foods (such as cheese or butter), milk or milkshakes, antacids, and supplements containing iron, aluminum, magnesium, calcium, selenium, zinc, or calcium. If you forget to take the Trombopag 50mg tablet, take your next dose at the usual time. Do not take more than one dose of this drug daily. Don’t stop taking this tablet without talking to your doctor. If your doctor advises you to stop treatment, your platelet count will be checked each week for four weeks. If you have any doubts regarding the use of this medicine, ask your doctor.
FAQs
Q 1. What is ITP?
Immune thrombocytopenia, also known as ITP, is a rare blood disorder. People with ITP have insufficient platelets in their blood. A low platelet count can cause bruising and bleeding.
Q 2. Who should not use the Trombopag 50mg tablet?
People with immune (primary thrombocytopenia (ITP) and children under one should not use Trombopag 50mg tablet. It is also not suggested for people with severe aplastic anemia and hepatitis C.
Q 3. Will you be monitored during treatment with the Trombopag 50mg tablet?
Yes, you will be monitored during the Trombopag 50mg tablet. Your healthcare provider will regularly access your white blood cell, platelets, blood clotting factors, heart rate, eye test, and complete blood count.
Q 4. Is it safe to take a Trombopag 50mg tablet on an empty stomach?
Yes, Trombopag 50mg tablet should be taken on an empty stomach. Because antacids, mineral and vitamin supplements (iron, calcium, magnesium, aluminum, selenium, and zinc), dairy products, calcium-enriched foods, and fortified juices interfere with this drug absorption. So, please take them at least two hours before or four hours after taking the medication.
Q 5. What happens if you discontinue using the Trombopag 50mg tablet?
If you discontinue using Trombopag 50mg tablet suddenly, it decreases platelet count as it can lead to severe bleeding. However, telling your healthcare practitioner before discontinuing this medication is advisable.
Q 6. How to store a Trombopag 50mg tablet?
Store Trombopag 50mg tablet at 25°C and out of the reach of children. After the expiration date, do not use this medication
Fact Box of Trombopag 50mg Tablet
| Molecule name: Eltrombopag | Therapeutic class: Anticoagulant |
| Pharmacological class: Thrombopoietin (TPO) receptor agonist | Indications:Â 1. Low platelet counts caused by immune primary thrombocytopenia (ITP) or hepatitis C virus (HCV) infection. 2. Severe aplastic anaemia. |
References
- Novartis Pharmaceuticals UK Limited, Electronic medicines compendium (EMC), [ Revised on Jan 2022] [Accessed on 22 May 2023], https://www.medicines.org.uk/emc/files/pil.508.pdf
- GlaxoSmithKline, US Food and Drug Administration, [ Revised on October 2008] [Accessed on 22 May 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/022291lbl.pdf
- Revolade, Annex I summary of Product Characteristics - European Medicines Agency. Available at: https://www.ema.europa.eu/en/documents/product-information/revolade-epar-product-information_en.pdf [Accessed on 22 May 2023].
Disclaimer
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