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Twinaqt Tablet
Last updated on 13 Jun 2026 | 07:27 AM (IST)
₹3015
MRP: ₹4302.56
(You Save ₹1287.56)
30 TABLET(s) IN A BOTTLE
Twinaqt Tablet contains dolutegravir and lamivudine, a fixed-dose combination used in the treatment of HIV infection. It works by inhibiting viral replication, helping reduce viral load and improve immune function. The tablet is taken orally as prescribed by a physician.
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Introduction
Twinaqt Tablet is a combination of antiretroviral medicine that contains two active substances, Dolutegravir and Lamivudine. It is indicated to treat Human Immunodeficiency Virus (HIV) in adults and adolescents over 12 who weigh at least 40 kg. HIV infection occurs when a person's immune system is attacked and weakened by the human immunodeficiency virus (HIV). This infection progressively weakens the immune system, making individuals more susceptible to opportunistic infections.
This drug is contraindicated and should not be used if you have any known allergy or hypersensitivity to this tablet or other ingredients in the medication. Antacids can interfere with the absorption of the drug and reduce its effectiveness. It is recommended not to take an antacid within 6 hours before or at least 2 hours after taking this tablet. You can take other acid-lowering medications, such as ranitidine, and omeprazole can be taken simultaneously with this tablet. You must consult your doctor for specific advice on taking acid-lowering medicines in conjunction with this medicine. Taking this tablet during the first weeks of pregnancy or when becoming pregnant may increase the risk of a malformed spinal cord in the baby. Inform your physician if you are pregnant, suspecting, or planning to get pregnant before taking this medicine. The doctor will explain the potential risks and benefits. Breastfeeding is not recommended because the viral infection can pass through breast milk with this Twinaqt Tablet.
Supplements or multivitamins with calcium, iron, or magnesium make the drug too difficult to absorb and reduce its effectiveness. Taking this tablet with food makes it possible to take these supplements concurrently. However, if you take it without food, avoid taking calcium, iron, or magnesium supplements for at least six hours before or two hours after taking the tablet. Consult your doctor for more guidance regarding using these supplements alongside Twinaqt Tablet. This tablet can interact with certain medications, potentially affecting their efficacy or increasing the risk of side effects. It's necessary to inform your doctor about all your medications, including prescription, over-the-counter, and herbal supplements, to ensure no potential Twinaqt drug interactions. Twinaqt price India varies by retailer and location.
Uses
Twinaqt uses are:
- Human Immunodeficiency Virus (HIV)
How Twinaqt Tablet Works
Twinaqt Tablet works by inhibiting different enzymes necessary for the replication of HIV. It blocks the integrase enzyme, preventing the insertion of viral DNA into the DNA of the host immune cells. The other drug inhibits the reverse transcriptase enzyme, essential for converting viral RNA into DNA
Interaction of Twinaqt Tablet with other drugs
Inform your doctor about all your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Twinaqt Tablet, reducing effectiveness by causing undesirable side effects.
Storage Conditions
- Store the Twinaqt Tablet at a controlled room temperature of (30°C).
- Keep it out of reach of children.
How to take Twinaqt Tablet
It is an orally available prescription drug. Your doctor will decide the Twinaqt dosage and duration of Twinaqt Tablet based on the disease condition and other factors. Always take this medicine as prescribed by your doctor. Take the tablet with or without food. Do not break, chew, or crush the tablet. Swallow the whole tablet with water.
Safety Advice for Twinaqt Tablet
Breast Feeding
Breastfeeding is not recommended because the viral infection can pass through breast milk with this Twinaqt Tablet.
Alcohol
It is unknown whether alcohol may interact with Twinaqt Tablet. Inform your physician if you drink alcoholic beverages.
Liver
You should tell your doctor if you have had liver diseases, including hepatitis B or C, before taking Twinaqt Tablet as they may reactivate the virus.
Lungs
It is unknown whether Twinaqt Tablet can be prescribed for patients with lung problems. Consult your doctor if you have any lung disease before starting the treatment.
Driving
Avoid driving if you feel unwell, as this Twinaqt Tablet, can make you feel dizzy and less alert.
Pregnancy
Taking Twinaqt Tablet during the first weeks of pregnancy or when becoming pregnant may increase the risk of a malformed spinal cord in the baby. Inform your physician if you are pregnant, suspecting, or planning to get pregnant before taking this medicine. The doctor will explain the potential risks and benefits.
Side Effects
Twinaqt side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Serious
- Severe allergic reactions (fever, rash, nausea, diarrhea, shortness of breath, swelling of the face or mouth, tiredness)
Common
- Headache
- Itching
- Dizziness, drowsiness
- Wind
- Stomach pain or discomfort
- Depression
- Difficulty sleeping, abnormal dreams
- Hair loss
- Muscle pain, joint pain
Expert tips
-
To prevent HIV transmission, never share needles, syringes, or any injecting equipment.
-
Always use sterile needles and syringes if using injectable drugs, and never share them with others.
-
Do not share personal items like toothbrushes, razor blades, or anything that may have blood or body fluids, as they can transmit HIV.
-
This medicine is unsafe for breastfeeding, as HIV can pass to the baby through breast milk. Use alternative feeding methods to support the infant’s nutrition.
-
If you forget to take Twinaqt Tablet for a day, take your usual dose the next day. Do not take a double dose.
FAQs about Twinaqt Tablet
Q1.
Can Twinaqt Tablet be used in combination with other drugs?
It can be combined with other antiretroviral drugs as an Twinaqt HIV treatment regimen. Combination therapy involving multiple antiretroviral drugs is the standard approach for treating HIV infection. This combination of medications from different drug classes helps to maximize the effectiveness of treatment and minimize the risk of developing drug resistance.
Q2.
What is the mechanism of action of Twinaqt Tablet?
Twinaqt Tablet work by inhibiting different enzymes that are necessary for the replication of HIV. It blocks the integrase enzyme, preventing the insertion of viral DNA into the DNA of the host immune cells. The other drug inhibits the reverse transcriptase enzyme, essential for converting viral RNA into DNA.
Q3.
What is the correct way to take Twinaqt Tablet?
Always take Twinaqt Tablet as prescribed by your doctor. Take the tablet with or without food. Do not break, chew, crush, or them. Swallow the whole with water.
Q4.
Whether Twinaqt Tablet are safe for breastfeeding?
Twinaqt Tablet is unsafe for breastfeeding because HIV infection can be easily passed to the baby through the breast milk, so it should be avoided.
Q5.
Who should not take Twinaqt Tablet?
Twinaqt Tablet should not be taken by individuals who are allergic to it or its ingredient`
Fact Box
|
Molecule name: |
Dolutegravir, Lamivudine |
|
Therapeutic class: |
Antiretrovirals |
|
Pharmacological class: |
1.Dolutegravir-Integrase inhibitors(INIs) 2.Lamivudine-Nucleoside reverse transcriptase inhibitors (NRTIs) |
|
Indications: |
Human Immunodeficiency Virus (HIV) |
References
- ViiV Healthcare UK Limited, Electronic medicines compendium (EMC), [ Revised on May 2021] [ Accessed on 17 May 2023],https://www.medicines.org.uk/emc/files/pil.10446.pdf
- Kandel CE, Walmsley SL, Dolutegravir - a review of the pharmacology, efficacy, and safety with the treatment of HIV, Drug Des Devel Ther., 2015, 7(9), 3547-55, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4500604/pdf/dddt-9-3547.pdf
- KD Tripathi, Essentials of Medical Pharmacology, Antiviral drugs, 7th edition, 2013, 807-808.
- Goodman & Gilman's, The Pharmacological Basis of Therapeutics, Antiretroviral agents and treatment of HIV infection, 12th edition, 2011, 1634-1635.
Disclaimer
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Author Details
Written By
Dr. B. Deiva
Pharm D
Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 13 Jun 2026 | 07:27 AM (IST)
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