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U-Frag 5000IU Injection
Prescription Required
Salt Composition : Urokinase
Manufacturer : BHARAT SERUMS & VACCINES LTD
Origin of Medicine : India
1 Vial(s)
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Introduction to U-frag 5000iu Injection
U-Frag 5000IU injection contains an active component of Urokinase. This medication is used to break down and dissolve blood clots that have formed within blood vessels, helping to restore blood flow and prevent serious complications like pulmonary embolism, deep vein thrombosis (DVT), peripheral arterial thrombosis, acute ischemic stroke, central venous catheter thrombosis and myocardial infarction (heart attack). Deep vein thrombosis (DVT) is the formation of blood clots in a deep vein, often in the legs. Pulmonary embolism (PE) is the blockage of a lung artery by a blood clot that travels from elsewhere in the body. Peripheral arterial thrombosis is the formation of blood clots in peripheral arteries, restricting blood flow to limbs. Acute ischemic stroke is the sudden loss of blood flow to the brain, leading to brain cell damage. Central venous catheter thrombosis formation of a blood clot around a catheter placed in a large vein. Myocardial infarction is damage to the heart muscle due to a blocked coronary artery.
Hypersensitivity reactions, including rash, swelling, difficulty breathing, or rapid heartbeat, can occur with this medication use. Patients require monitoring for allergic symptoms, and medical attention is sought if any signs of hypersensitivity appear. U-Frag 5000IU injection is contraindicated in individuals with active internal bleeding, bleeding disorders, recent brain/spinal/eye surgery, severe uncontrolled hypertension, intracranial neoplasm, bacterial endocarditis, or aneurysm/vascular malformation. These contraindications help ensure the safe use of this medication based on specific medical conditions and risks. U-Frag 5000IU injection may be recommended for use in children and the elderly in specific medical situations, but its use requires a thorough evaluation by healthcare professionals.
Uses of U-frag 5000iu Injection
U-Frag 5000IU injection is used to treat the following:
- Deep vein thrombosis (DVT)
- Pulmonary embolism (PE)
- Peripheral arterial thrombosis
- Acute ischemic stroke
- Central venous catheter thrombosis
Therapeutic Effects of U-frag 5000iu Injection
U-Frag 5000IU injection operates by converting plasminogen into plasmin, an enzyme responsible for breaking down fibrin, a protein essential for blood clot formation. By facilitating the dissolution of clots, this medication helps restore blood flow in conditions like thrombosis, embolism, and stroke.
Interaction of U-frag 5000iu Injection with other drugs
Inform the doctor about your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with U-Frag 5000IU injection, reducing effectiveness by causing undesirable side effects.
More Information about U-frag 5000iu Injection
- Store at room temperature, between 20°C to 25°C (68°F to 77°F).
- Keep away from moisture, heat, and light.
- It should not be frozen.
- Keep away from children and pets.
How to consume U-frag 5000iu Injection
U-Frag 5000IU injection is typically administered intravenously (IV) through a vein, allowing direct delivery into the bloodstream. This route ensures rapid distribution throughout the body, enabling its thrombolytic action to dissolve blood clots and restore blood flow in various medical conditions such as deep vein thrombosis, pulmonary embolism, and acute ischemic stroke.
Safety Advices for U-frag 5000iu Injection
Pregnancy
Pregnant women or those planning to become pregnant should discuss all potential risks and benefits of using U-Frag 5000IU injection with their healthcare provider.
Breast Feeding
Due to the potential for U-Frag 5000IU injection to be excreted into breast milk and its potential effects on the nursing infant,always consult a healthcare provider.
Lungs
The medication's effects and potential risks may be influenced by pre-existing lung conditions. Before using U-Frag 5000IU injection or any medication, individuals with lung issues should consult a healthcare provider.
Liver
The metabolism and clearance of U-Frag 5000IU injection may be affected in patients with liver dysfunction, potentially leading to altered drug levels and an increased risk of bleeding or other adverse effects. Before using this medication, individuals with liver conditions should consult a healthcare provider.
Alcohol
It is generally advisable to avoid alcohol consumption while undergoing U-Frag 5000IU injection treatment. Alcohol can affect blood clotting and may potentially increase the risk of bleeding or other complications.
Driving
It is important to consider potential indirect effects, such as bleeding complications or side effects like dizziness or weakness, which could impact your ability to drive safely.
Side Effects of U-frag 5000iu Injection
U-Frag 5000IU injection cause some side effects like all medications, although not everyone will experience them.
Serious:
- Bleeding
- Allergic reactions
- Drop in blood pressure
Common:
- Bleeding or bruising
- Nausea or vomiting
- Fever
- Low blood pressure
- Flushing
- Chest pain
Word of Advice
When using U-Frag 5000IU injection, it's important to take several precautions to ensure safe and effective treatment. Consider the potential risks and benefits, especially if you have a history of bleeding disorders, allergies, liver or kidney impairment, lung conditions, or recent surgery. Pregnant or breastfeeding individuals should consult their healthcare provider. Monitor for signs of bleeding, allergic reactions, or changes in blood pressure. Inform your healthcare provider about all medications and supplements you're taking. Be cautious if this affects your ability to drive or operate machinery. Patients with stroke history, recent trauma, hypertension, or clotting disorders need close monitoring. Promptly report any adverse effects, and maintain regular communication with your healthcare provider for tailored guidance throughout Uokinase therapy.
FAQs
Q 1. Can U-Frag 5000IU injection be self-administered at home?
U-Frag 5000IU injection is typically administered by healthcare professionals in a controlled medical setting due to its potential risks and the need for close monitoring.
Q 2. What should I do if I miss a dose of U-Frag 5000IU injection?
U-Frag 5000IU injection is administered under medical supervision, so missing a dose is unlikely. If you have concerns, consult your healthcare provider.
Q 3. How long does U-Frag 5000IU injection treatment usually last?
The duration of U-Frag 5000IU injection treatment varies based on the specific condition being treated and individual patient factors. Your healthcare provider will determine the appropriate duration.
Q 4. Does U-Frag 5000IU injection have any effect on fertility?
There is limited information available on U-Frag 5000IU injection's effects on fertility. Consult your healthcare provider if you have concerns.
Q 5. How often will I need blood tests while on U-Frag 5000IU injection treatment?
Blood tests may be conducted regularly to monitor clotting parameters and overall health. Your healthcare provider will determine the appropriate testing schedule.
Q 6. Are the side effects of U-Frag 5000IU injection reversible once treatment is stopped?
Most side effects, such as bleeding or other reactions, are typically reversible once treatment with U-Frag 5000IU injection is discontinued under medical supervision.
Fact Box of U-frag 5000iu Injection
Molecule name: Urokinase | Therapeutic class: Fibrinolytic agent |
Pharmacological class: Thrombolytics | Indications: 1. Deep vein thrombosis (DVT) 2. Pulmonary embolism (PE) 3. Peripheral arterial thrombosis 4. Acute ischemic stroke5. Central venous catheter thrombosis |
References
- Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Blood coagulation and anticoagulant, fibrinolytic, and antiplatelet drugs, 12th edition, 2011, 852.
- KD Tripathi, Essentials of Medical Pharmacology, Drugs affecting Coagulation, bleeding and thrombosis, 7th edition, 2013, 627.
- Syner-Medica Ltd, Electronic medicines compendium (EMC), [Revised on 27th Jul 2023] [ Accessed on 7th August 2023], https://www.medicines.org.uk/emc/product/264/smpc#gref
Disclaimer
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