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UNIZOX 1GM INJECTION_103351 (1)
UNIZOX 1GM INJECTION_103351 (2)
UNIZOX 1GM INJECTION_103351 (3)
UNIZOX 1GM INJECTION_103351 (1)
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Unizox 1gm Injection

Prescription Required

Salt Composition : Ceftizoxime

Manufacturer : UNITED BIOTECH PVT LTD

Origin of Medicine : India

MRP: ₹448
Price : ₹380
You Save : ₹68 (15%)

1 Vial(s)

Pincode
Delivery By -

Introduction to Unizox 1gm Injection

Unizox 1gm injection contains an active component as Ceftizoxime.  It treats various bacterial infections by interfering with the bacteria's ability to form cell walls, ultimately leading to their death. It is generally used when infections are suspected to be caused by bacteria that are resistant to other antibiotics or when a broader spectrum of coverage is needed. This medication is commonly prescribed to treat infections such as urinary tract infections (UTIs), respiratory tract infections, skin and soft tissue infections, intra-abdominal infections, and certain types of sepsis. It may treat cellulitis, abscesses, and other skin and soft tissue infections caused by susceptible bacteria. This medication might treat infections within the abdominal cavity, such as peritonitis, caused by susceptible bacteria. Cellulitis is a bacterial skin infection characterized by red, swollen, and painful areas caused by bacteria entering the skin through a wound or opening. Urinary tract infections (UTIs) are bacterial infections affecting the urinary system, causing frequent urination, pain, and discomfort.

Unizox 1gm injection should not be used in individuals with known hypersensitivity to cephalosporin antibiotics or penicillins due to the risk of allergic reactions. You should not use this medication if you have a history of severe allergic reactions (such as anaphylaxis) to beta-lactam antibiotics. Additionally, inform your doctor if you have a kidney disease, as this medication is primarily eliminated through the kidneys. When considering its usage in children, healthcare providers will determine appropriate dosages based on weight and closely monitor for adverse reactions. For older people, it's important to change the amount of Unizox 1gm injection they take based on how well their kidneys work. We also need to watch out for any interactions with other medications they might be taking, make sure they drink enough fluids and take care of their overall health. These steps are necessary to ensure that Unizox 1gm injection is safe and works well for them.


Uses of Unizox 1gm Injection

Unizox 1gm injection is used in the following:

  • Urinary tract infections (UTIs)
  • Respiratory tract infections
  • Skin and soft tissue infections
  • Intra-abdominal infections
  • Gynecological infections
  • Sepsis and bloodstream infections
  • Surgical prophylaxis
  • Bone and joint infections
  • Bacterial meningitis

Therapeutic Effects of Unizox 1gm Injection

Unizox 1gm injection interferes with bacterial cell wall synthesis by inhibiting the formation of peptidoglycan, a crucial cell wall component. This weakens the cell wall's integrity, leading to bacterial cell lysis and death. This medication primarily targets gram-negative bacteria and is effective against many bacterial species.


Interaction of Unizox 1gm Injection with other drugs

Inform the doctor about your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Unizox 1gm injection, reducing effectiveness by causing undesirable side effects. 


More Information about Unizox 1gm Injection

  • Store at room temperature, up to 20°C to 25°C.
  • Keep away from moisture, heat, and light.
  • It should not be frozen.
  • Keep away from children and pets.

How to consume Unizox 1gm Injection

Unizox 1gm injection can be administered through two main routes: intravenous (IV), where the medication is directly infused into a vein for rapid effect, and intramuscular (IM), which involves injection into a muscle for slower absorption. The choice between these routes depends on the severity of the infection and the patient's condition, as determined by healthcare professionals.


Safety Advices for Unizox 1gm Injection

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Pregnancy

  

It is unknown whether Unizox 1gm injection is safe in pregnancy or not, so it should be used during pregnancy only if clearly needed and under the guidance of a healthcare provider.

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Breast Feeding

  

Unizox 1gm injection is generally considered safe during breastfeeding. However, it's important to consult a healthcare professional before using it to assess potential risks and benefits.

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Lungs

  

When considering Unizox 1gm injection for individuals with lung conditions, it's important to communicate your medical history to your healthcare provider.

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Liver

  

Unizox 1gm injection should be used cautiously in individuals with pre-existing liver conditions. It's important to inform your healthcare provider about any past liver problems you have or had. 

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Alcohol

  

It's advisable to avoid alcohol consumption while taking Unizox 1gm injection. Alcohol is unsafe while taking this medication as it might interfere with the effectiveness of the medication and increase the risk of side effects.

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Driving

  

Some individuals might experience side effects like dizziness or drowsiness. If these side effects occur, caution should be exercised while driving or operating machinery.


Side Effects of Unizox 1gm Injection

Unizox 1gm injection causes some side effects like all medications, although not everyone will experience them. 

Serious:

  • Anaphylactic reactions
  • Clostridium difficile-associated diarrhea (CDAD)

Common:

  • Gastrointestinal disturbances
  • Skin reactions
  • Injection site reactions
  • Fever and liver enzyme elevation

Word of Advice

Individuals with known allergies to cephalosporin antibiotics or penicillins must exercise caution due to the potential for allergic reactions. Before starting Unizox 1gm injection, give a complete medical history, including kidney disorders, gastrointestinal conditions like colitis, liver problems, bleeding disorders, and diabetes, to the doctor. Special attention is needed for pediatric and older adult patients, as dosages might require adjustment based on age-related factors. 

Those with lung conditions or bleeding disorders require close attention. Prolonged or inappropriate antibiotic use can lead to antibiotic-resistant organisms' development, so use it only as the doctor prescribes. Individuals with impaired renal function require close monitoring, and caution should be exercised in immunosuppressed patients. Individuals should for check regularly the signs of allergic reactions, bleeding issues, or changes in glucose test results. Sticking to the complete course of treatment, even if symptoms improve, is important. Maintaining a open communication with healthcare providers and adhering to their guidance is important for safety.


FAQs

Q 1. Should I complete the full course of Unizox 1gm injection treatment?

Yes, it's important to complete the full course of treatment as prescribed by your healthcare provider, even if your symptoms improve before the course is finished.

Q 2. What should I do if I experience adverse reactions with Unizox 1gm injection?

If you experience severe allergic reactions, difficulty breathing, or any unusual symptoms while taking Unizox 1gm injection, seek medical attention immediately.

Q 3. Can Unizox 1gm injection cause antibiotic resistance?

Prolonged or inappropriate use of antibiotics can contribute to antibiotic resistance. Using Unizox 1gm injection responsibly as prescribed can help mitigate this risk.

Q 4. Can I adjust the dosage of Unizox 1gm injection on my own?

Dosage adjustments should always be made under the guidance of a healthcare provider. Self-adjusting dosages can lead to inadequate treatment or increased risks of side effects.

Q 5. Can Unizox 1gm injection interfere with birth control?

Unizox 1gm injection does not typically interfere with hormonal birth control methods like birth control pills. However, it's advisable to discuss potential interactions with your healthcare provider.

Q 6. Can I drink grapefruit juice while taking Unizox 1gm injection?

Unizox 1gm injection does not have a known interaction with grapefruit juice. However, it's always advisable to consult your healthcare provider about any potential interactions with your specific medications.


Fact Box of Unizox 1gm Injection

Molecule name:  Ceftizoxime

Therapeutic class: Antibacterial agents

Pharmacological class: Third-generation cephalosporins

Indications: 

1. Urinary tract infections (UTIs)

2. Respiratory tract infections

3. Skin and soft tissue infections

4. Intra-abdominal infections

5. Gynecological infections

6. Sepsis and bloodstream infections

7. Surgical prophylaxis

8. Bone and joint infections

9. Bacterial meningitis


References

  1. Ceftizoxime: a third-generation cephalosporin active against anaerobic bacteria, Committee on Antimicrobial Agents,  [Published on 1st Jun 1990] [Accessed on 14th August 2023] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1452577/
  2. Fujisawa Healthcare, Inc., [Revised on Aug 2007] [Accessed on 14th Aug 2023], https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=3574df06-fec5-4888-8080-3b817addfb02&type=display
  3. KD Tripathi, Beta-Lactam Antibiotics, Essentials of Medical Pharmacology, 8th Edition, 2019, 766-783.

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