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Vaprin 50mg Tablet
Prescription Required
Salt Composition : Azathioprine
Manufacturer : ZYDUS CADILA
Origin of Medicine : India
10 Tablet(s) In A Strip
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Introduction to Vaprin 50mg Tablet
Vaprin 50mg Tablet contains an active component as Azathioprine. It is an immunosuppressive medication used to treat various autoimmune diseases and to prevent organ rejection after organ transplantation.It can help reduce joint inflammation and pain in people with rheumatoid arthritis.This medication is used to manage conditions like Crohn's disease and ulcerative colitis, helping to control inflammation in the gastrointestinal tract.It can be used to treat certain manifestations of lupus when other treatments are not sufficient. Rheumatoid arthritis is a chronic autoimmune disorder that causes inflammation and pain in the joints, affecting mobility and joint function.Crohn's disease is a chronic inflammatory bowel disease that affects the digestive tract, causing symptoms like abdominal pain, diarrhea, and weight loss. Ulcerative colitis is a chronic inflammatory bowel disease that leads to inflammation and ulcers in the colon and rectum.
Vaprin 50mg Tablet can cause hypersensitivity reactions in some individuals, leading to symptoms like rash, swelling, fever, nausea, and blood disorders. The immunosuppressive effects of this medication can make it difficult for the body to fight infections. Therefore, it is typically avoided in individuals with active infections.It should be avoided in patients with severe bone marrow suppression or blood disorders. In cases of severe kidney dysfunction,its use should be carefully considered and also needs close monitoring. It is generally not recommended for individuals with active malignancies or a history of certain cancers due to its potential to increase the risk of malignancy. Vaprin 50mg Tablet can be used in children and older adults for certain autoimmune conditions and organ transplantation, but its use requires careful monitoring due to age-related factors and potential risks.
Uses of Vaprin 50mg Tablet
Vaprin 50mg Tablet is used in the following:
- Autoimmune diseases
- Inflammatory bowel diseases (IBD)
- Organ transplantation
- Autoimmune hepatitis
Therapeutic Effects of Vaprin 50mg Tablet
Vaprin 50mg Tablet involves being converted into an active metabolite called 6-mercaptopurine within the body. 6-mercaptopurine is a purine analog, and it interferes with the synthesis of DNA and RNA in rapidly dividing cells, including immune cells. This disruption of nucleic acid synthesis suppresses the activity of the immune system by inhibiting the proliferation of immune cells. As a result, this medication reduces the production of antibodies and immune cells responsible for attacking the body's tissues in autoimmune diseases. The immunosuppressive effect helps to alleviate inflammation and control the symptoms of autoimmune conditions while also preventing the body from rejecting transplanted organs.
Interaction of Vaprin 50mg Tablet with other drugs
Inform the doctor about your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Vaprin 50mg Tablet, reducing effectiveness by causing undesirable side effects.Â
More Information about Vaprin 50mg Tablet
- Store at room temperature, between 20°C to 25°C (68°F to 77°F).
- Keep away from moisture, heat, and light.
- It should not be frozen.
- Keep away from children and pets.
How to consume Vaprin 50mg Tablet
Vaprin 50mg Tablet can be administered through oral (by mouth) route. It is available in the form of tablets or oral suspension for easy ingestion. It is important to follow the recommended dosage and schedule for this medication to ensure its effectiveness and safety in treating various medical conditions.
Safety Advices for Vaprin 50mg Tablet
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Pregnancy
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Vaprin 50mg Tablet is generally not recommended during pregnancy, as it may harm the developing fetus.
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Breast Feeding
 ÂVaprin 50mg Tablet is generally not recommended during breastfeeding as it pass into breast milk.
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Lungs
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If you experience anyrespiratory symptoms, such as cough, shortness of breath, or chest pain, promptly inform your healthcare provider.
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Liver
  It is advisable to limit or avoid alcohol consumption while taking Vaprin 50mg Tablet, as alcohol can interact with the medication and increase the risk of liver problems.Always consult a health care provider if you have any liver problems.
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Alcohol
 ÂIt is essential to seek guidance from a qualified healthcare professional to understand potential risks and ensure it is safe based on your individual health and circumstances.
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Driving
  Vaprin 50mg Tablet may cause dizziness or drowsiness in some individuals. If you experience these side effects, avoid driving or operating heavy machinery until you know how the medication affects you.
Side Effects of Vaprin 50mg Tablet
Azoran 50mg Tablet causes some side effects like all medications, although not everyone will experience them.Â
Serious:
- Severe allergic reactions
- Severe liver problems
- Pancreatitis
- Severe bone marrow suppression
- Interstitial Pneumonitis
- Serious Infections
- Development of malignancies (including lymphoma)
Common:
- Nausea and vomiting
- Diarrhea
- Loss of appetite
- Rash or skin reactions
- Headache
- Hair loss
- Increased susceptibility to infections
- Bone marrow suppression (anemia, leukopenia, thrombocytopenia)
Word of Advice
Inform your healthcare provider of any allergies, liver or kidney problems, ongoing infections, and pre-existing medical conditions. Vaprin 50mg Tablet can weaken the immune system, increasing the risk of infections, so avoid close contact with sick individuals. Regular blood tests are necessary to monitor blood cell counts, and genetic testing may help optimize dosing for some individuals. Practice sun protection, limit alcohol consumption, and discuss family planning options if needed.Always take this medication as prescribed, attend regular check-ups, and be vigilant for any side effects or changes in your health.Â
FAQs
Q 1. How long does it take for Vaprin 50mg Tablet to start working?
The response to Vaprin 50mg Tablet can vary among individuals and depends on the medical condition being treated. It may take several weeks to months to experience the full benefits of the medication. Your healthcare provider will monitor your progress and adjust the treatment plan as needed.
Q 2. Can I stop taking Vaprin 50mg Tablet if my symptoms improve?
No, do not stop taking Vaprin 50mg Tablet without consulting your healthcare provider, even if your symptoms improve. Suddenly stopping the medication can lead to a flare-up of the underlying condition or organ rejection after transplantation. Always follow your doctor's instructions regarding the dosage and duration of treatment.
Q 3. Can Vaprin 50mg Tablet cause pancreatitis?
In rare cases, Vaprin 50mg Tablet may cause pancreatitis, characterized by severe abdominal pain, nausea, and vomiting. Seek immediate medical attention if you experience such symptoms.
Q 4. What should I do if I miss a dose of Vaprin 50mg Tablet?
If you miss a dose of Vaprin 50mg Tablet, take it as soon as you remember. However, if it is close to the time of your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.
Q 5. Can Vaprin 50mg Tablet be used to treat COVID-19 or viral infections?
Vaprin 50mg Tablet is not effective against viral infections like COVID-19. It is primarily used to manage autoimmune conditions and prevent organ rejection after transplantation. Always consult your healthcare provider for appropriate treatment options for viral infections.
Q 6. Can I receive live vaccines while on Vaprin 50mg Tablet?
Avoid receiving live vaccines while on Vaprin 50mg Tablet, as the medication can weaken the immune response to live vaccines. Consult your healthcare provider for vaccination recommendations while on immunosuppressive therapy.
Fact Box of Vaprin 50mg Tablet
Molecule name: Azathioprine | Therapeutic class:Â Immunomodulator |
Pharmacological class: Immunosuppressive agents | Indications:Â 1. Autoimmune diseases 2.Inflammatory bowel diseases (IBD) 3. Organ transplantation 4.Autoimmune hepatitis |
References
- Mylan, Electronic Medicines Compendium (EMC), [Revised on 05 Aug 2022] [Accessed on 7th August 2023], https://www.medicines.org.uk/emc/product/2540/smpc#gref
- Sebela Pharmaceuticals Inc., US Food & Drug Administration, [Revised on Dec 2018] [Accessed on 7th August 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/016324s039lbl.pdf
- O Mohammedi, Kassim TA, Azoran 75mg Tablet, NCBI Bookshelf, [Revised on Ist May, 2023.], [Accessed on7th August 2023 ], https://www.ncbi.nlm.nih.gov/books/NBK542190/
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