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Vascel 20mg Injection
Prescription Required
Salt Composition : Vasopressin
Manufacturer : CELON LABORATORIES LTD
Origin of Medicine : India
1 Ampoule(s)
Introduction to Vascel 20mg Injection
Vascel 20mg Injection contains an active component of vasopressin. It is also known as antidiuretic hormone (ADH), is a peptide hormone that plays a crucial role in maintaining water balance and regulating blood pressure in the body. This medication can be used for diabetes insipidus. This medication has been used as an alternative to epinephrine in some cases of cardiac arrest. In certain cases of severe hemorrhagic shock (life-threatening blood loss), it may be used to help increase blood pressure and support vital organ perfusion. Diabetes insipidus is a rare disorder characterized by excessive thirst and urination due to the insufficient production or response to antidiuretic hormone (Vascel 20mg Injection). Cardiac arrest is a sudden and life-threatening condition where the heart stops beating, leading to a cessation of blood flow and loss of consciousness.
One of the primary functions of this medication is to regulate water balance in the body. It also has vasoconstrictive effects on blood vessels. During times of physical or emotional stress, this medication is released as part of the body's stress response. It aids in water conservation and increases blood pressure to cope with stress. This medication has been linked to various social behaviors and bonding in certain animal species, including pair bonding and maternal behaviors.
It can manifest as allergic reactions or other adverse effects and requires careful monitoring and management by healthcare professionals during administration. Vascel 20mg Injection's water-retaining effects can potentially lead to low sodium levels (hyponatremia) if not appropriately monitored. Its vasoconstrictive effects can cause a significant increase in blood pressure. Therefore, it should be used cautiously in patients with hypertension or other cardiovascular conditions. Caution is required for proper dosage adjustment and monitoring in pediatric and elderly patients during its administration.
Uses of Vascel 20mg Injection
Vascel 20mg Injection is used to treat the following:
- Diabetes Insipidus
- Cardiac Arrest
- Hemorrhagic Shock
Therapeutic Effects of Vascel 20mg Injection
Vascel 20mg Injection acts by binding to V2 receptors in the kidneys to increase water reabsorption, reducing urine output in diabetes insipidus. In cardiac arrest, it targets V1 receptors in blood vessels, causing vasoconstriction, elevating blood pressure, and improving blood flow during resuscitation. In severe hemorrhagic shock, its vasoconstrictive effects help maintain blood pressure and support vital organ perfusion until definitive treatment can be provided. Proper monitoring and dosing are essential due to their potent cardiovascular effects.
Interaction of Vascel 20mg Injection with other drugs
Inform the doctor about your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Vascel 20mg Injection, reducing effectiveness by causing undesirable side effects.
More Information about Vascel 20mg Injection
- Store at room temperature, between 20°C to 25°C (68°F to 77°F).
- Keep away from moisture, heat, and light.
- It should not be frozen.
- Keep away from children and pets.
How to consume Vascel 20mg Injection
Vascel 20mg Injection can be administered through various routes, including intravenous (IV), intramuscular (IM), subcutaneous (SC), and intranasal, depending on the medical condition and the need for rapid or sustained effects. Proper administration should be done under the supervision of healthcare professionals to ensure safety and effectiveness.
Safety Advices for Vascel 20mg Injection
Pregnancy
During pregnancy, Vascel 20mg Injection should only be used when necessary and under the guidance of a healthcare professional. Close monitoring and consideration of potential risks are essential to ensure the well-being of both the mother and the baby.
Breast Feeding
The safety of Vascel 20mg Injection during breastfeeding is not well-established, and its use should be approached with caution. Before using this medication while breastfeeding, healthcare providers should be consulted.
Lungs
Regarding Vascel 20mg Injection, it is crucial to exercise caution when using this medication in patients with lung-related conditions, as it can potentially cause or worsen lung-related complications.
Liver
Caution should be exercised when using Vascel 20mg Injection in patients with liver conditions, as impaired liver function may affect drug metabolism.
Alcohol
Avoid consuming alcohol while taking Vascel 20mg Injection, as it may enhance side effects and disrupt water balance. Follow your healthcare provider's advice for safety and effectiveness.
Driving
The safety of driving while taking Vascel 20mg Injection can vary depending on individual responses to the medication. It may cause side effects such as dizziness, drowsiness, or blurred vision, impairing driving ability.
Side Effects of Vascel 20mg Injection
Vascel 20mg Injection causes some side effects like all medications, although not everyone will experience them.
Serious:
- Allergic reactions
- Chest pain or irregular heartbeats
- Severe headache
- Confusion
- Changes in mental state
- Seizures
- Severe abdominal pain or cramping
Common:
- Nausea or vomiting
- Stomach cramps
- Headache
- Dizziness or lightheadedness
- Runny or stuffy nose
- Increased thirst
- Water retention or swelling
Word of Advice
Caution should be exercised to monitor for severe allergic reactions, cardiovascular effects, and hyponatremia. Special care is required for patients with hepatic or renal impairment, the elderly, and pediatric patients, as they may have altered responses. During pregnancy and breastfeeding, the use of Vascel 20mg Injection should be approached cautiously, and potential drug interactions need to be considered. Excessive dosing or prolonged use might lead to tolerance and overdose risks. Patients with cardiovascular diseases, allergies to oxytocin, or epilepsy require close monitoring. Proper administration, dilution, and monitoring of intravenous infusions are essential, and intranasal formulations must adhere to recommended dosages to avoid complications. Awareness of the risk of water intoxication and gangrene is crucial, as is monitoring peripheral circulation. Careful assessment and active patient involvement are fundamental in ensuring the safe and effective use of this medication.
FAQs
Q 1. What should I do if I miss a dose of Vascel 20mg Injection?
If you miss a dose of Vascel 20mg Injection, contact your healthcare provider for guidance on what to do. Do not double the dose to make up for the missed one.
Q 2. Can Vascel 20mg Injection cause electrolyte imbalances?
Vascel 20mg Injection can cause hyponatremia (low sodium levels) due to its water-retaining effects. Monitoring electrolyte levels is important, especially in patients at risk of imbalances.
Q 3. Can Vascel 20mg Injection be used to treat septic shock?
While Vascel 20mg Injection has been studied to treat septic shock, it is not the first-line treatment and should be used with caution and under the supervision of a healthcare professional.
Q 4. Can Vascel 20mg Injection be used to stop bleeding during surgery?
Vascel 20mg Injection has been used to reduce bleeding during specific surgical procedures due to its vasoconstrictive effects. However, it should be administered by experienced healthcare professionals to avoid complications.
Q 5. Is there a risk of dependency on long-term Vascel 20mg Injection use?
Vascel 20mg Injection replacement therapy for diabetes insipidus is not typically associated with dependency. However, it is essential to follow the prescribed treatment plan and regular medical check-ups.
Q 6. Can Vascel 20mg Injection cause water intoxication?
Excessive Vascel 20mg Injection administration can lead to water retention and potentially cause water intoxication, leading to electrolyte imbalances. Proper dosing and monitoring are crucial to avoid this complication.
Fact Box of Vascel 20mg Injection
Molecule name: Vasopressin | Therapeutic class: Antidiuretic Agents |
Pharmacological class: Endogenous Peptide Hormone | Indications: 1. Diabetes Insipidus 2.Cardiac Arrest 3. Hemorrhagic Shock |
References
- KD Tripathi, Essentials of Medical Pharmacology, Antidiuretic drugs, 7th edition, 2013, 593-596.
- Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Regulation of renal function and vascular volume, 12th edition, 2011, 701-713.
- Mercury Pharmaceutical Ltd, Electronic medicines compendium (EMC), [Revised on 27 May 2022)] [Accessed on 29th May 2023], https://www.medicines.org.uk/emc/product/4117/smpc#gref
- American Regent, US Food and Drug Administration, [Revised on August 2020] [Accessed on 29th July],https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/212593s000lbl.pdf
Disclaimer
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