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Verz 200mg Tablet
Prescription Required
Salt Composition : Voriconazole
Manufacturer : DR REDDY'S LABORATORIES LTD
Origin of Medicine : India
4 Tablet(s) In A Strip
Introduction to Verz 200mg Tablet
Verz 200mg tablet is an antifungal drug that contains an active ingredient called Voriconazole. It belongs to the medication class known as fungal ergosterol synthesis inhibitor. It is is prescribed for severe, life-threatening fungal infections and as a preventive measure for high-risk individuals, including those who have undergone bone marrow transplantation. This medicine should not be given to children younger than 2 years of age.Â
Do not take this medicine if you are allergic to Voriconazole or other medical ingredients. Before taking Verz 200mg tablet, it is important to notify your doctor if you have had an allergic reaction to other azoles, suffer from or have a history of liver disease, or have cardiomyopathy, irregular heartbeat, slow heart rate, or an abnormality of the electrocardiogram (ECG) called 'long QTc syndrome'. Additionally, it is crucial to avoid sunlight and sun exposure during treatment, protecting the skin with clothing and high-SPF sunscreen. Children should also follow these precautions. Some common side effects include fever, rash, nausea, vomiting, diarrhea, headache, swelling of the extremities, stomach pain, and breathing difficulties.
While on Verz 200mg tablet, promptly inform your doctor if you experience a sunburn, severe skin rash or blisters, bone pain, signs of adrenal insufficiency (chronic fatigue, muscle weakness, appetite loss, weight loss, abdominal pain), or signs of Cushing's syndrome (weight gain, fatty hump, rounded face, darkened skin, thinning skin, easy bruising, high blood sugar, excessive hair growth, excessive sweating). Inform your doctor if you have a known intolerance to certain sugars before taking this medicine because it contains lactose.Â
Uses of Verz 200mg Tablet
- Invasive Aspergillosis
- Candidemia in non-neutropenic patients
- Esophageal candidiasis
- Fungal infections (caused by Scedosporium apiospermum, Fusarium spp., and Fusarium solani)
- Candida infections
- Fungal infections in high-risk bone marrow transplant patients
Therapeutic Effects of Verz 200mg Tablet
Verz 200mg tablet works by blocking the production of ergosterol, disrupting fungal cell membranes and leading to cell death, ultimately eliminating the infection.
Interaction of Verz 200mg Tablet with other drugs
Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional or vitamin supplements, and herbal products you take or have taken before the treatment. Certain medications may interact with Verz 200mg tablet and can cause undesirable side effects.
More Information about Verz 200mg Tablet
- Keep out of sight and reach of pets and children.
- Do not freeze the medicine.
- Do not store above 30°C.
- Always check the expiry date before consuming it.
How to consume Verz 200mg Tablet
Take the Verz 200mg tablet as your physician advises. Usually, the tablets will be taken with or without food. Do not crush, chew, or open the medicine. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. Only stop taking the tablet if your doctor advises you to stop.
Safety Advices for Verz 200mg Tablet
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Pregnancy
 ÂAvoid taking Verz 200mg tablet during pregnancy unless directed by your doctor. Use effective contraception and notify your doctor immediately if you become pregnant while taking medicine.
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Breast Feeding
 ÂLimited information is available on using Verz 200mg tablet during breastfeeding. So, before starting the treatment, inform your doctor if you are breastfeeding. Contact your doctor for more information.
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Lungs
 ÂIt is unknown whether Verz 200mg tablet is safe for patients with lung problems. Inform your physician if you have any lung disease before starting the treatment. Contact your doctor if you experience any lung-related symptoms.
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Liver
 ÂVerz 200mg tablet should be used cautiously in liver patients. Before starting the treatment, notify your doctor about pre-existing liver conditions. Dose adjustment is needed in such conditions. Your doctor will check your liver to monitor its functions.Â
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Alcohol
 ÂIt is unsafe to consume alcohol while taking Verz 200mg tablet.
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Driving
 ÂVerz 200mg tablet could alter the driving ability or operating machinery capacity by causing blurred vision or uncomfortable sensitivity to light.
Side Effects of Verz 200mg Tablet
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Serious
- Rash
- Visual disturbances
- Liver problems
- Arrhythmias and QT prolongation
- Jaundice (Changes in blood tests of liver function)
- Pancreatitis (inflammation of the pancreas)
Common
- Fever, headache
- Nausea, vomiting, diarrhea
- Swelling of the extremities
- Itchiness and rashes
- Sinusitis
- Pain in the stomach, back
- Blood in urine
- Seizures
- Low BP
- Hair loss
- Low levels of glucose, sodium, potassium, WBC, platelet
- Neutrophil counts in the blood.
Word of Advice
Liver and heart patients should take Verz 200mg tablet cautiously and inform their doctor about all the underlying medical conditions. Do not stop the medicine until your doctor advises. Do not double-dose the medicine to make up for a forgotten dose.Â
Unless your doctor advises, do not consume this medicine if you are pregnant or breastfeeding while taking Verz 200mg tablet. Notify your doctor if you experience any serious side effects. Your medical professional will inform you if you need any dose adjustments. Contact your doctor for more information.
FAQs
Q 1. How does Verz 200mg tablet work?
Verz 200mg tablet inhibits ergosterol production, disrupting fungal cell membranes and leading to cell death, thereby eliminating the infection and relieving symptoms.
Q 2. Can you take Verz 200mg tablet when pregnant?
Consult your medical professional regarding the use of Verz 200mg tablet during pregnancy. The potential benefits and risks should be carefully assessed. Your doctor will suggest taking this medicine only if it's necessary.
Q 3. How long does Verz 200mg tablet take to work?
The effectiveness of Verz 200mg tablet can vary among individuals and depends on the specific fungal infection being treated. While some people may experience symptom improvement within a few days, others may require several weeks to see noticeable results. Discuss with your doctor for more information.
Q 4. What should I do if I miss a dose of Verz 200mg tablet?
If you miss a capsule dose, take it as soon as possible. However, if it's close to the time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose the Verz 200mg tablet.
Q 5. What are the side effects of Verz 200mg tablet?
Some common side effects of Verz 200mg tablet are nausea, vomiting, diarrhea, swelling of the extremities, itchiness and rashes, sinusitis, pain in the stomach and back, blood in urine, seizures, and hair loss.
Fact Box of Verz 200mg Tablet
Molecule Name: Voriconazole | Therapeutic class: Antifungal drug |
Pharmacological class: Fungal ergosterol synthesis inhibitor | Indications:Â 1. Invasive Aspergillosis 2. Candidemia in non-neutropenic patients 3. Esophageal candidiasis 4. Fungal infections (caused by Scedosporium apiospermum, Fusarium spp., and Fusarium solani) 5. Candida infections 6. Fungal infections in high-risk bone marrow transplant patients |
References
- Pfizer, Electronic Medicines Compendium (EMC), [Revised on Jul 2021] [Accessed on 02nd June 2023], https://www.medicines.org.uk/emc/files/pil.7976.pdf
- D.H. Dockrell, S. Sundar, B.J. Angus, R.P. Hobson, Infectious disease, Davidson’s Principles and Practice of Medicine, 22nd Edition, 2014, 293-386.
- Dr. Reddy’s Laboratories (UK) Ltd., Electronic Medicines Compendium (EMC), [Revised on July 2022] [Accessed on 02nd June 2023] PACKAGE LEAFLET: INFORMATION FOR THE USER (medicines.org.uk)
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