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Vincristine GLS 1mg Injection
Prescription Required
Salt Composition : Vincristine Sulphate
Manufacturer : GLS PHARMA LTD
Origin of Medicine : India
1 Vial(s)
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Introduction to Vincristine Gls 1mg Injection
Vincristine GLS 1mg Injection is a chemotherapy medication containing the active constituent Vincristine sulphate. This medication belongs to a class of drugs called vinca alkaloids, which inhibit the growth of cancer cells. It treats blood, head, breast, neck, kidney, bone, or lung cancers. It is used in treating rhabdomyosarcoma (cancer that affects muscle tissue) and neuroblastoma (cancer that develops from immature nerve cells). It may also be used to treat multiple myeloma (cancer of plasma cells), thyroid cancer, and a blood disorder known as idiopathic thrombocytopenic purpura (ITP). Cancer is a disorder in which cells multiply in an uncontrolled and abnormal manner.
This chemotherapy medicine should not be used if you have an untreated infection or Charcot-Marie-Tooth syndrome (a disorder that causes weakness in the leg muscles). Talk to your physician if you have breathing problems, mental health illness, liver disorders, low blood cell count, or nervous disorders, or if you are having radiotherapy before taking Vincristine GLS 1mg Injection. Like all chemotherapy drugs, it can cause side effects, such as nausea, vomiting, constipation, hair loss, and fatigue. Patients should discuss the potential benefits and risks of treatment with their doctor.
Uses of Vincristine Gls 1mg Injection
Vincristine GLS 1mg Injection used in the treatment of:Â
- Cancers of blood, head, neck, breast, kidney, bone, or lung
- Idiopathic thrombocytopenic purpura (ITP)
- Multiple myeloma
- Rhabdomyosarcoma
- Thyroid cancer
- Neuroblastoma
Therapeutic Effects of Vincristine Gls 1mg Injection
The therapeutic effect of Vincristine GLS 1mg Injection is to inhibit the growth and spread of cancer cells. It disrupts the formation and function of microtubules, which are structures inside cells that help with cell division and movement. By interfering with microtubule function, this medication can prevent cancer cells from dividing and multiplying and can also cause them to die.
Interaction of Vincristine Gls 1mg Injection with other drugs
Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Vincristine GLS 1mg Injection Injection and reduce effectiveness by causing undesirable side effects.
More Information about Vincristine Gls 1mg Injection
- Vincristine GLS 1mg Injection should be stored at 2 °C - 8°C
- Protect it from light.
- Keep it in its original packaging until it is ready to be used.
- Keep reach out of the reach of children and pets.
- Should be disposed of properly.
How to consume Vincristine Gls 1mg Injection
Vincristine GLS 1mg Injection is usually administered intravenous injection (IV) by a healthcare professional in a hospital or clinical setting. It should not be taken orally or applied topically to the skin. If you miss a dose, then do not double the dose to make up for the missed one.
Safety Advices for Vincristine Gls 1mg Injection
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Pregnancy
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Vincristine GLS 1mg Injection is unsafe during pregnancy as it can cause fetal harm. It is s recommended to avoid this medication during pregnancy.
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Breast Feeding
 ÂYou need to talk to your doctor if you are breastfeeding before taking Vincristine GLS 1mg Injection. It may cause harm to the baby.
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Lungs
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Vincristine GLS 1mg Injection is used to treat lung cancer, but like all chemotherapy drugs, it can cause several side effects, including those that affect the lungs. In rare cases, it can cause pulmonary toxicity, which is damage to the lungs that can lead to breathing difficulties, coughing, and other respiratory symptoms. So it is better to consult a doctor if you have any concerns or pre-existing lung disease.
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Liver
  Vincristine GLS 1mg Injection is primarily metabolized in the liver, so inform your healthcare provider if you have any liver problems or diseases. In some cases, it may cause liver toxicity, leading to elevated liver enzymes or other liver problems.Â
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Alcohol
 ÂIt is recommended to avoid consuming alcohol while taking Vincristine GLS 1mg Injection, as alcohol can increase the risk of certain side effects associated with the medication, such as stomach ulcers or gastrointestinal bleeding.
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Driving
  Patients receiving Vincristine GLS 1mg Injection should be advised to avoid driving or operating machinery if they experience side effects such as fatigue, dizziness, or blurred vision, impairing a patient's ability to drive or operate machinery safely.
Side Effects of Vincristine Gls 1mg Injection
Like all medications, Vincristine GLS 1mg Injection Injection can cause side effects, although not everyone who takes it will experience them.Â
Serious:
- Severe allergic reactions
- Pulmonary toxicity (lung damage)
- Liver toxicity
- Neurotoxicity (damage to the nervous system)
- Tumor lysis syndrome (life-threatening complication in which cancer cells release their contents into the bloodstream)
Common:
- Nausea and vomiting
- Constipation
- Loss of appetite
- Hair loss
- Fatigue
- Muscle weakness
- Numbness or tingling in the hands and feet (peripheral neuropathy)
- Increased risk of infection
- Easy bruising or bleeding
- Mouth sores
- Changes in mood or behavior
- Difficulty sleeping
Word of Advice
If you are receiving Vincristine GLS 1mg Injection, it's important to be proactive in managing your treatment and monitoring your symptoms. Keep a close line of communication with your healthcare provider and report any concerns or side effects as soon as possible. Avoid getting pregnant and breastfeeding during treatment. Take steps to care for yourself physically and emotionally during treatment, and seek support from loved ones and professionals as needed. Maintain a healthy and balanced diet during treatment to support your overall health and well-being. By being informed and engaged in your treatment, you can help ensure the best possible outcomes and manage any potential risks or complications.
FAQs
Q 1. Can Vincristine GLS 1mg Injection be used to treat other conditions besides cancer?
Vincristine GLS 1mg Injection is primarily used to treat various types of cancer. However, it may also be used to treat certain non-cancerous conditions, such as autoimmune disorders.
Q 2. Is Vincristine GLS 1mg Injection available in oral form?
No, Vincristine GLS 1mg Injection is only available as an injectable solution administered by a healthcare provider.
Q 3. Can Vincristine GLS 1mg Injection cause hair loss?
Yes, hair loss is a potential side effect of Vincristine GLS 1mg Injection treatment, but it is usually temporary and reversible after treatment is completed.
Q 4. Can Vincristine GLS 1mg Injection cause nerve damage?
Yes, nerve damage is a potential side effect of Vincristine GLS 1mg Injection treatment, and patients receiving this medication should be monitored closely for any signs of neuropathy.
Q 5. Can Vincristine GLS 1mg Injection be used in children?
Yes, Vincristine GLS 1mg Injection can be used in children, but the dose and administration frequency may differ from those used in adults.
Q 6. Can Vincristine GLS 1mg Injection affect fertility?
Yes, Vincristine GLS 1mg Injection may cause temporary or permanent infertility in both men and women. Patients need to discuss their fertility concerns with their healthcare provider before starting treatment.
Fact Box of Vincristine Gls 1mg Injection
Molecule name: Vincristine sulphate | Therapeutic class: Anticancer |
Pharmacological class: Vinca alkaloids | Indications:Â 1. Cancers of the blood, head, neck, breast, kidney, bone, or lung 2. Idiopathic thrombocytopenic purpura (ITP) 3. Multiple myeloma 4. Rhabdomyosarcoma 5. Thyroid cancer 6. Neuroblastoma |
References
- Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Cytotoxic agents, 12th edition, 2011, 1707.
- KD Tripathi, Essentials of Medical Pharmacology, Anticancer drugs, 7th edition, 2013, 865.
- Hospira UK Ltd, Electronic medicines compendium (emc), [Revised on March 2022] [ Accessed on 18 April 2023], https://www.medicines.org.uk/emc/files/pil.1501.pdf
- Hospira, Inc, US Food and Drug Administration, [Revised on July 2013] [ Accessed on 18th April 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/071484s042lbl.pdf
- Jan Skubnik et al; Vincristine in Combination Therapy of Cancer: Emerging Trends in Clinics; Biology; Published on 31/08/2021; ; Accessed on 18th April 2023; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8468923/
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