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Zoladex LA 10.8mg Injection
Prescription Required
Salt Composition : Goserelin Acetate
Manufacturer : ASTRAZENECA PHARMA INDIA LTD
Origin of Medicine : United Kingdom
1 Prefilled Syringe(s)
Introduction to Zoladex La 10.8mg Injection
Zoladex LA 10.8mg injection, containing Goserelin Acetate, is an LHRH agonist used in chemotherapy. For men, it treats localized and advanced prostate cancer, both alone and with other drugs. Women use it for advanced breast cancer, endometriosis, uterine fibroids, and as a pre-surgery endometrial thinner. It also assists in treating infertility when combined with other medications.
This injection lowers testosterone in men and estrogen in women. Avoid use during pregnancy or breastfeeding. Notify your doctor if you have heart issues or experience mood changes such as depression or anxiety. Not suitable for children. Common side effects include hot flashes, urinary problems, and sexual dysfunction in men, and hot flashes, acne, sweating, and depression in women.
Uses of Zoladex La 10.8mg Injection
- In men, it is used in combination with other medications to treat prostate cancer, while in women, it treats advanced breast cancer.
- Used to treat endometriosis (A disorder in which tissue that normally lines the uterus grows outside the uterus) and uterine fibroids.
- Serves as an endometrial-thinning agent prior to uterine surgery and aids in treating infertility in women when used with other medications.
Therapeutic Effects of Zoladex La 10.8mg Injection
Zoladex LA 10.8mg injection belongs to luteinizing hormone-releasing hormone (LHRH) agonists. It works by inhibiting certain hormones, which may stimulate the growth of cancer cells. In males, it reduces testosterone levels; in females, it reduces estrogen levels.
Interaction of Zoladex La 10.8mg Injection with other drugs
Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional and vitamin supplements, and herbal products. Certain medications may interact with Zoladex LA 10.8mg injection and reduce effectiveness by causing undesirable side effects.
More Information about Zoladex La 10.8mg Injection
- Store Zoladex LA 10.8mg injection in the original package at room temperature ( Do not exceed 25°C)
- Keep away from children and pets
- If you miss an appointment to receive the injection, discuss it with your healthcare professional and reschedule the appointment.
How to consume Zoladex La 10.8mg Injection
Inform your healthcare provider about all the medicines you take, including prescription and over-the-counter medications, as well as nutritional and vitamin supplements, and herbal products. Certain medications may interact with the injection, reducing its effectiveness and causing undesirable side effects.
Safety Advices for Zoladex La 10.8mg Injection
Pregnancy
Zoladex LA 10.8mg injection should not be used during pregnancy. It can cause fetal harm. Inform your physician if you are pregnant or planning to get pregnant. It is necessary to consult a physician before starting the treatment.
Breast Feeding
Zoladex LA 10.8mg injection should not be used during breastfeeding. It is excreted in breast milk and causes harm to the unborn baby. Inform your physician if you are breastfeeding and get advice.
Lungs
It is unknown whether Zoladex LA 10.8mg injection can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.
Liver
It is safe to administer Zoladex LA 10.8mg injection in patients with liver disorders. No dose adjustment is required. Consult your physician for more advice.
Alcohol
It is not known whether it is safe to consume alcohol with Zoladex LA 10.8mg injection. Please consult your doctor.
Driving
Taking Zoladex LA 10.8mg injection does not usually affect your ability to drive. Please consult the doctor for more advice.
Side Effects of Zoladex La 10.8mg Injection
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Common:
- Acne
- Hot flushes and Sweating
- Swelling in the hands and legs
- Headache
- Depression and mood swings
- Erectile dysfunction
- Sexual dysfunction
- Pain, bruising, and bleeding
- Pain while urinating ( in men)
- Dryness or itching of the vagina
- Thinning of bones
Serious:
- Increased blood pressure
- Increased risk of Heart failure
- Increased risk of Diabetes
- Increased risk of stroke
- Injection site injury
- Severe skin reactions
Word of Advice
Before starting treatment, inform your physician about any existing health conditions you have, such as heart, diabetes, kidney, liver, or lung disorders. Males experiencing difficulty urinating should notify their doctor immediately. Avoid if you are allergic to goserelin or any of its ingredients. The duration of your treatment will vary based on your medical needs. While on this medication, avoid birth control pills and consider alternative contraceptive methods like condoms, diaphragms, or cervical caps.
FAQs
Q 1. How is Zoladex LA 10.8mg injection typically given (administered)?
Zoladex LA 10.8mg injection will be given to you by your healthcare professional. It is given under the skin (subcutaneously) in your stomach area every 4 weeks. Your doctor will decide the dose and duration of the therapy based on your condition and how well you respond to the treatment.
Q 2. Is Zoladex LA 10.8mg Injection considered chemotherapy?
Yes, Zoladex LA 10.8mg Injection is a chemotherapeutic agent used to treat hormone-sensitive cancers, such as breast and prostate cancers, as well as benign gynecological disorders, such as endometriosis and uterine fibroids. It also assists in reproductive treatments and manages precocious puberty.
Q 3. Can the Zoladex LA 10.8mg injection taken with other medications like paracetamol or ibuprofen?
The duration of Zoladex treatment varies; consult your doctor for specific guidance. You can take medications such as paracetamol, ibuprofen, or norethisterone concurrently with Zoladex.
Q 4. Is Zoladex LA 10.8mg injection used to treat infertility in women?
Yes, Zoladex LA 10.8mg injection is used in combination with other drugs to treat infertility in women.
Q 5. What are Zoladex LA 10.8mg Injection implants??
Zoladex LA 10.8mg Injection implants, containing the active ingredient goserelin acetate, are administered subcutaneously in the stomach area.
Fact Box of Zoladex La 10.8mg Injection
Molecule name: Goserelin Acetate | Therapeutic class: luteinizing hormone-releasing hormone (LHRH) agonists |
Pharmacological class: Anti-Neoplastic drug | Indications: 1. Prostate cancer in men 2. Breast cancer in women 3. Endometriosis 4. Uterine fibroids 5. Female infertility |
References
- Package leaflet: Information for the user Zoladex 3.6 mg Implant goserelin. (2015). [online] Available at: https://www.medicines.org.uk/emc/files/pil.1543.pdf [Accessed 24 Jan. 2023].
- HIGHLIGHTS OF PRESCRIBING INFORMATION. (2015). [online] Available at: https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/019726s050s051s052lbl.pdf [Accessed 24 Jan. 2023].
- HIGHLIGHTS OF PRESCRIBING INFORMATION. (2015b). [online] Available at: https://documents.tersera.com/zoladex-us/3.6mg_MagnumPI.pdf [Accessed 24 Jan. 2023].
- Tripathi, K.D. (2019). Essentials of medical pharmacology. New Delhi: Jaypee Brothers Medical Publishers, pp.263–264 [Accessed 24 Jan. 2023].
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