This page contains brief details about the drug , it's indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Background and Date of Approval

Acebrophylline+acetylcysteine is approved for medical use for treating COPD (Chronic obstructive pulmonary disease) and asthma.

Mechanism of Action of undefined

Acebrophylline is involved in bronchodilation, muco-regulation, and reduces inflammation and acetylcysteine is an antioxidant which is involved in mucolytic activity. The mucoprotein is involved in the secretion of mucus and cellular debris  in  increasing its secretion in lungs. Acetylcysteine by this way decreases the viscosity of mucus and is involved in  pulmonary regulation activity.

Uses of undefined

Acebrophylline+acetylcysteine is used to treat chronic bronchopulmonary disease, acute   bronchopulmonary disease, pulmonary complication of cystic fibrosis, bronchial asthma, COPD (Chronic obstructive pulmonary disease), asthma.

undefined Drug administaration and Dosage available

Acebrophylline+acetylcysteine is available as a tablet which is administered orally with the advice of a doctor. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition.

Warnings, Precautions and Side Effects of undefined

Warnings

People who have allergies to the medicine or any of its ingredients should inform their doctor. Inform your doctor if you have phenylketonuria, angina attacks (tightness in your chest, neck, and arm), or cough before taking the medicine. Acebrophylline + acetylcysteine may pass through the placenta of pregnant women. Consult your doctor if you are planning to get pregnant or think you may be pregnant or while you are breastfeeding.

Precautions

The safety and effectiveness of the drug have not been established in children under 12 years. So, it is recommended to consult your doctor before taking the drug. The medicine should be taken as per the doctor's instructions. Acebrophylline + acetylcysteine should be administered with caution to individuals who habitually consume alcohol, as it may lead to unwanted side effects in such patients. So, it is important to inform your doctor before taking the medicine.

Side Effects

The common side effects that are experienced while you are on the treatment with  Acebrophylline+acetylcysteine, nausea, abdominal pain, headache.

Word Of Advice

Individuals with gastrointestinal problems should be cautious while taking the medicine to avoid undesirable side effects. Inform your doctor about your prescribed and non-prescribed medicine and take a proper diet while under medication. Avoid eating junk foods and get plenty of fresh air if you have nausea. It is recommended to avoid or limit your alcohol consumption during the acebrophylline + acetylcysteine medication. You may feel abdominal pain during the medication. Speak with your doctor if you have persistent abdominal pain.

Frequently Asked Question

References

  1. Lamp San Prospero S.p.A., Electronic medicines compendium (EMC), [ Revised on Aug 2021] [ Accessed on 11th Oct 2023] https://www.medicines.org.uk/emc/files/pil.2488.pdf
  2. KD Tripathi, Essentials of Medical Pharmacology, Antitubercular drugs, 7th edition, 2013, 771.
  3. Goodman & Gilman’s, Chemotherapy of Tuberculosis, Mycobacterium avium complex disease, and Leprosy, 12th edition, 2011, 1562-1563.
  4. Sumit Roy Tapadar et al., The Effect of Acebrophylline vs Sustained Release Theophylline in Patients of COPD- A Comparative Study,Journal of clinical and diagnostic research, Published on Sep 2014; Accessed on 11/10/2023;https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4225926
  5. Rivka S. Horowitz et al., Placental Transfer of N-Acetylcysteine Following Human Maternal Acetaminophen Toxicity, taylor and francis, Published on 29 Jul 2009; Accessed on 11/10/2023;https://www.tandfonline.com/doi/epdf/10.3109/15563659709001226?needAccess=true

Disclaimer

The drug information on this page is not a substitute for medical advice, it is meant for educational purposes only. For further details consult your doctor about your medical condition to know if you are eligible to receive this treatment.