This page contains brief details about the drug , it's indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Background and Date of Approval

Amino acids are approved as nutritional supplements to improve the nutritional status of patients with chronic disease.

Mechanism of Action of undefined

Amino acids operate by undergoing a process called transamination by taking nitrogen from some non-essential amino acids. This process decreases the formation of urea and prevents the accumulation of uremic toxins, thus improving kidney health. Additionally, it ensures the intake of essential amino acids.

Uses of undefined

Amino acids are vital for mechanical support, nerve generation and impulses, immune protection, cell and tissue growth, and coordination in the human body. These supplements are used as an adjuvant in improving the nutritional status of kidney, liver, and elderly patients. They may also be effective in weight loss and help improve mood and sleep.

undefined Drug administaration and Dosage available

Amino acids are available in the form of powder, granules and tablets. The dose and frequency vary according to body weight and disease condition.

Warnings, Precautions and Side Effects of undefined

Warnings

During the amino acids treatment, your doctor may periodically monitor your serum calcium, serum phosphate, and other kidney parameters to prevent serious complications. Report to your doctor if you have been diagnosed with hereditary phenylketonuria.

Precautions

Aminoacids usually don’t impact the health of pregnant women and breastfeeding mothers. However, exercise caution and discuss with your doctor before using amino acid supplements or any combination tablets during pregnancy and breastfeeding.

Side Effects

Amino acids are not associated with any serious side effects. However, hypercalcemia is the most common side effect.

Word Of Advice

Your healthcare provider will regularly monitor your serum calcium levels to check for hypercalcemia and suggest reducing the intake of calcium and vitamin D sources.

Eat a calorie-rich diet. Take amino acids only on your healthcare provider’s recommendation. Inform your doctor if you have any other kidney disease and about all the underlying medical conditions. Do not stop the medicine until your doctor advises. Do not double-dose the medicine to make up for a forgotten dose. Notify your doctor if you experience any serious side effects. Your medical professional will inform you if you need any dose adjustments. Contact your doctor for more information.

Frequently Asked Question

References

  1. Rivpra formulation PVT LTD, [Revised on Jan 2021] [Accessed on Nov 2023], https://www.centaurpharma.com/downloads/2021/nephrology/NEFROGARD.pdf
  2. Alexander Zemchenkov, Irina N.Konakova; Efficacy of the Essential Amino Acids and Keto-Analogues on the CKD progression rate in real practice in Russia - city nephrology registry data for outpatient clinic; BMC Nephrology; [Published on 07/07/2016]; [Accessed on 23/11/2023] https://bmcnephrol.biomedcentral.com/articles/10.1186/s12882-016-0281-z
  3. Arun Sharma et al.; Rationale of α-Ketoanalogue Supplemented with Low Protein Diet for the Treatment of Chronic Kidney Disease; Journal of Karnali Academy of Health Sciences; [Published on 09/01/2021]; [Accessed on 23/11/2023]; https://jkahs.org.np/jkahs/index.php/jkahs/article/view/415/222
  4. Che-Hsiung Wu et al.; Ketoanalogues supplementation decreases dialysis and mortality risk in patients with anemic advanced chronic kidney disease; [Published on 05/05/2021]; [Accessed on 23/11/2023]; http://www.ncbi.nlm.nih.gov/pmc/articles/pmc5419544/

Disclaimer

The drug information on this page is not a substitute for medical advice, it is meant for educational purposes only. For further details consult your doctor about your medical condition to know if you are eligible to receive this treatment.