This page contains brief details about the drug , it's indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Background and Date of Approval
The combination of Cannabis Leaf Extract, Ashwagandha (Withania somnifera), Brahmi (Bacopa monnieri), and Tulsi (Ocimum sanctum) represents a synergy of traditional and modern herbal medicine. Each component is known for its distinct therapeutic benefits, and together, they offer a comprehensive solution for managing stress, anxiety, cognitive decline, and chronic pain.
Recent clinical trials have focused on this combination’s potential in addressing anxiety-related disorders, neurodegenerative diseases, and chronic inflammatory conditions. Studies conducted in 2020-2023 have demonstrated its efficacy in reducing cortisol levels, enhancing cognitive function, and alleviating chronic pain. Regulatory bodies in countries like India, Australia, and parts of Europe have approved this herbal blend as a complementary therapy, recognising its safety profile and effectiveness in integrative healthcare settings.
Mechanism of Action of undefined
This unique combination works through multiple synergistic mechanisms:
- Endocannabinoid System Modulation: Cannabis Leaf Extract interacts with CB1 and CB2 receptors, helping regulate pain, inflammation, and mood, while also providing anxiolytic effects.
- Adaptogenic and Neuroprotective Actions: Ashwagandha and Brahmi act as adaptogens, reducing cortisol levels and enhancing the body's resilience to stress. Brahmi further supports cognitive function by promoting neurogenesis and synaptic plasticity.
- Anti-Inflammatory and Antioxidant Properties: Tulsi and Cannabis Leaf Extract reduce oxidative stress and inflammation by modulating inflammatory cytokines and enhancing antioxidant enzyme activity.
- Holistic Stress Reduction: This combination balances the HPA (hypothalamic-pituitary-adrenal) axis, reducing the physiological impact of chronic stress and improving overall well-being.
Together, these mechanisms offer a holistic approach to managing stress, anxiety, chronic pain, and cognitive decline.
Uses of undefined
This herbal combination is widely used for:
- Stress and Anxiety Management: Effective in reducing cortisol levels, promoting relaxation, and improving sleep quality.
- Cognitive Enhancement: Beneficial for memory, focus, and concentration, especially in conditions like mild cognitive impairment and early-stage dementia.
- Pain and Inflammation Relief: Suitable for chronic pain conditions such as arthritis, fibromyalgia, and neuropathic pain.
- Immune System Support: Enhances immune resilience by modulating inflammatory pathways and boosting antioxidant activity.
- Mood Regulation: Helpful in managing symptoms of mild depression and mood swings.
undefined Drug administaration and Dosage available
This combination is available in various forms, including:
- Capsules/Tablets: Commonly dosed at 250-500 mg per day, depending on the condition being treated.
- Tinctures/Oils: Often administered sublingually for faster absorption, with dosage adjusted based on individual needs.
- Powdered Form: Can be mixed with water or herbal teas, typically 1-2 teaspoons per day.
Dosage should be personalised and guided by a healthcare professional, depending on the individual’s age, weight, and condition.
Warnings, Precautions and Side Effects of undefined
Warnings
- Psychoactive Effects: Products containing higher THC levels may cause mild euphoria or drowsiness.
- Drug Interactions: Potential interactions with sedatives, antidepressants, and immunosuppressants.
- Pregnancy and Breastfeeding: Not recommended due to limited safety data during these periods.
Precautions
- Allergic Reactions: Monitor for signs of allergies, such as rash, itching, or breathing difficulties.
- Mental Health Conditions: Use cautiously in individuals with a history of psychiatric disorders.
- Monitoring: Regular follow-ups are advised for long-term users to monitor liver and kidney function.
Side Effects
Common side effects may include:
- Mild drowsiness
- Dry mouth
- Gastrointestinal discomfort
- Dizziness
- Nausea
Serious side effects are rare but may include allergic reactions or altered liver enzyme levels.
Word Of Advice
Consult a healthcare provider before starting this combination, especially if you are on medication for chronic conditions or have underlying health issues. Proper dosage and monitoring are essential for safe and effective use.
Frequently Asked Question
References
Disclaimer
This information is intended for educational purposes only and should not replace professional medical advice. Always consult your healthcare provider for personalised guidance.
