Uses of undefined

Casirivimab + Imdevimab is available as an injection. It is used to treat patients with confirmed acute COVID-19 infection. It is also indicated to prevent acute COVID-19 infection. Acute covid-19 infection is caused by a virus called coronavirus. People can get COVID-19 through contact with another person who has the virus. 

undefined Drug administaration and Dosage available

Casirivimab + Imdevimab is given as an infusion into your vein that lasts for 20 to 30 minutes, or it can be given as a subcutaneous (under the skin) injection. This injection will be given to you by a doctor or nurse who is experienced in the use of this type of treatment. They will monitor you closely while you are being given this medicine. Do not self-administer this medicine.

Warnings, Precautions and Side Effects of undefined

Warnings

This drug is indicated to cause severe hypersensitivity and infusion reactions like fever, difficulty breathing, reduced oxygen saturation, chills, fatigue, arrhythmia (e.g., atrial fibrillation, tachycardia, bradycardia), chest pain or discomfort, weakness, altered mental status, nausea, headache, bronchospasm, hypotension, hypertension, angioedema, throat irritation, rash including urticaria, pruritus, myalgia, vasovagal reactions (e.g., pre-syncope, syncope), dizziness, and diaphoresis. Inform your physician immediately if you experience any of these symptoms after receiving the injection. 

Precautions

Do not take Casirivimab + Imdevimab if you are allergic to Casirivimab + Imdevimab or any other ingredients. This medicine can cause allergic reactions following the infusion or injection; notify your physician immediately if you face any of the infusion reactions. Before you take this injection, inform your doctor if you have been vaccinated against COVID infection. Inform your doctor if you are pregnant or breastfeeding before initiating the treatment.   

Inform your healthcare provider about all your medicines, including prescription, over-the-counter, nutritional, vitamin supplements, and herbal products. Certain medications interact with Casirivimab + Imdevimab, reducing their effectiveness by causing undesirable side effects.

Side Effects

The side effects of Casirivimab + Imdevimab are injection site reactions like swelling, redness, and infusion reactions such as skin rash, nausea, vomiting, difficulty breathing, swelling in the face, feet, and hands, and cough. 

Word Of Advice

Store in a refrigerator (2°C to 8°C). Do not freeze. Protect the medicine from light and excessive moisture. Keep the medicine out of reach of children and pets. If you missed the dosing schedule, inform your healthcare professional immediately and reschedule. Self isolate and use infection control measures (eg, wearing mask, social distancing, avoid sharing personal items, clean and disinfecting “high touch” surfaces, and frequent handwashing). The most common side effects may include infusion-related reactions such as swelling in the hands, face, and feet, skin rash, breathing difficulties, cough, abdominal pain, and chest pain. Injection site reactions like swelling and redness at the injection site can also occur. 

Frequently Asked Question

• How effective is Casirivimab + Imdevimab in treating COVID-19? 
• Clinical studies have shown that Casirivimab + Imdevimab can significantly reduce the risk of hospitalization or death in high-risk individuals with COVID-19. However, the effectiveness may vary depending on individual factors, including the illness's severity and specific variants of the virus.

• Can Casirivimab + Imdevimab be used in combination with other COVID-19 treatments?
• Casirivimab + Imdevimab can be used alone or in combination with other COVID-19 treatments as determined by healthcare professionals. It is important to consult with healthcare providers to ensure proper treatment coordination and minimize potential interactions.

• How soon after testing positive for COVID-19 should Casirivimab + Imdevimab be administered?
• Casirivimab + Imdevimab is most effective when administered early after testing positive for COVID-19, ideally within 10 days of symptom onset. Early treatment helps reduce the severity of illness and the risk of hospitalization.

• Can Casirivimab + Imdevimab be used in pediatric patients?
• Yes, Casirivimab Can Casirivimab + Imdevimab be used as a substitute for COVID-19 vaccination?    

• Can Casirivimab + Imdevimab be used as a substitute for COVID-19 vaccination?  
• No, Casirivimab + Imdevimab is not a substitute for COVID-19 vaccination. Vaccination is the most effective way to prevent COVID-19 and its complications. Casirivimab + Imdevimab is specifically used for the treatment of individuals who have already tested positive for the virus and are at high risk of developing the infection.