This page contains brief details about the drug , it's indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Background and Date of Approval

Cefixime + Potassium clavulanate was approved by U.S. Food and Drug Administration in 1989.

Mechanism of Action of undefined

Cefixime + Potassium clavulanate acts by blocking the synthesis of bacteria cell walls, which is essential for survival. It kills susceptible bacteria and stops the spread of diseases.

Potassium clavulanate is a beta-lactamase inhibitor (enzyme) that is produced by some bacteria that can inactivate and destroy certain antibiotics, including cephalosporins. 

Combining Cefixime + Potassium clavulanate with potassium clavulanate inhibits the activity of beta-lactamase enzymes produced by bacteria, preventing them from breaking down Cefixime + Potassium clavulanate. This allows Cefixime + Potassium clavulanate to remain active and exert its antimicrobial effect against susceptible bacteria.

Uses of undefined

Cefixime + Potassium clavulanate is indicated to treat bacterial infections of the nose, ear, throat, chest, lungs, urinary tract, and uncomplicated gonorrhea.

undefined Drug administaration and Dosage available

Tablet: Take the prescribed dose of Cefixime + Potassium clavulanate tablet by using the measuring cup or dosing syringe, or the dropper provided by the pack. Shake the pack well before each use.

Syrup: Take the prescribed dose of Cefixime + Potassium clavulanate syrup by using the measuring cup or dosing syringe, or the dropper provided by the pack. Shake the pack well before each use.

Warnings, Precautions and Side Effects of undefined

Warnings

Report to your physician immediately if you experience allergic reactions to Cefixime + Potassium clavulanate, other cephalosporin antibiotics, or any of the other ingredients of this medicine. Tell your doctor before treatment commencement with this medication if you have kidney or liver disease. 

Precautions

Consult your doctor before using this medication if you are pregnant or plan to have a baby. Cefixime + Potassium clavulanate should not be taken while pregnant unless specifically advised by your doctor. Avoid breastfeeding your baby while on the treatment with this medication. It is unknown if this medicine passes into the breast milk.

Side Effects

The side effects known to occur commonly during the treatment with Cefixime + Potassium clavulanate are nausea, stomach pain, diarrhea, indigestion (dyspepsia), headache, dizziness, flatulence (accumulation of gas), and itching. 

Word Of Advice

It is advised not to stop taking this medication on your own. Please consult your doctor before stopping this medication, as it makes the infection worsen and hard to treat. Driving or using machinery should be avoided as it may cause confusion and drowsiness. 

Frequently Asked Question

References

  1. KD Tripathi, Essentials of Medical Pharmacology, Beta-lactam antibiotics, 7th Edition, 2013, 726-728.
  2. Lupin Limited; US Food & Drug Administration, [Revised on May 2012], [Accessed on 13/05/2023 ], https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/203195s000lbl.pdf
  3. Sanofi., Electronic medicines compendium (EMC), [Revised on April 2022] [Accessed on 13/05/2023 ], https://www.medicines.org.uk/emc/files/pil.5534.pdf
  4. Shelly Rainforth Collins;  Clavulanate Potassium; Accessed on 13/05/2023; https://www.sciencedirect.com/topics/medicine-and-dentistry/clavulanate-potassium

Disclaimer

The drug information on this page is not a substitute for medical advice; it is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you are eligible to receive this treatment.