This page contains brief details about the drug , it's indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Background and Date of Approval
Cilostazol was initially approved by the United States Food and Drug Administration (FDA) for medical use in the United States in 1999.
Mechanism of Action of undefined
Cilostazol is a selective phosphodiesterase III (PDE3) inhibitor in various cells, mainly in platelets. Inhibiting PDE3 increases intracellular cAMP (cyclic adenosine monophosphate) levels in platelets and vascular smooth muscle cells. Increased cAMP levels lead to decreased intracellular calcium concentrations, inhibiting platelet aggregation and vasodilation. This dual antiplatelet and vasodilatory effect helps improve blood flow, reduce thrombus formation, and alleviate symptoms associated with peripheral arterial disease and intermittent claudication.
Uses of undefined
Cilostazol is primarily used for the management and improvement of intermittent claudication. Additionally, it is prescribed for peripheral arterial disease (PAD) to enhance blood flow and reduce the risk of thrombosis
undefined Drug administaration and Dosage available
Cilostazol is administered orally in the form of tablets. It is taken orally with or without food, as directed by a healthcare professional. The recommended starting dosage and any necessary dose adjustments are determined based on the specific condition being treated and the patient's response to the medication.
Warnings, Precautions and Side Effects of undefined
Warnings
Cilostazol can increase the risk of bleeding. This medication may affect the cardiovascular system, potentially leading to palpitations or worsening certain heart conditions. It can lead to an allergic reaction, such as rash, itching, swelling, dizziness, or difficulty breathing.
Precautions
It is important to be cautious before taking Cilostazol if you have a bleeding disorder or are taking other blood-thinning medications.If you experience irregular heartbeat or chest pain, seek medical attention promptly. If you develop signs of an allergic reaction, such as rash, itching, swelling, dizziness, or difficulty breathing, stop taking cilostazol and seek immediate medical help.
Side Effects
Common side effects of Cilostazol include headache, diarrhea, abnormal stools, palpitations, and fast or irregular heartbeat. Other possible side effects may include dizziness, weakness, and increased heart rate. Some individuals may experience bleeding, including gastrointestinal bleeding or bruising. Allergic reactions, though rare, are possible and may manifest as rash, itching, swelling, dizziness, or trouble breathing.
Word Of Advice
Cilostazol can increase the risk of bleeding, so it is important to be cautious if you have a bleeding disorder or are taking other blood-thinning medications. It may also affect your heart and cause palpitations, so be watchful if you have any heart conditions. People with liver or kidney problems should use it carefully and may need adjustments in their dosage. If you have had recent surgery or known allergies to it or any other medications, inform your doctor. It can interact with other medications, so let your healthcare provider know about all the drugs you are taking. If you have heart failure, a bleeding disorder, or are older, consult your doctor before taking this medication.
It is a good idea to consult your healthcare provider about consuming alcohol while taking this medication. Always follow your doctor's advice, and if you experience any unusual symptoms, let your doctor know immediately.
Frequently Asked Question
References
- Mylan, Electronic medicines compendium (EMC), [Revised on 9th Mar 2020] [Accessed on 19th Oct 2023],https://www.medicines.org.uk/emc/product/2609/smpc#gref
- Otsuka America Pharmaceutical Inc., US Food and Drug Administration, [Revised on July 2017 ] [Accessed on 19th 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/020863s024lbl.pdf
Disclaimer
The drug information on this page is not a substitute for medical advice; it is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you can receive this treatment.
