Uses of undefined

Efavirenz, Emtricitabine and Tenofovir disoproxil Fumarate is indicated as a complete regimen to treat human immunodeficiency virus infection in adults and paediatric patients older than 12 years of age.

undefined Drug administaration and Dosage available

Efavirenz, Emtricitabine and Tenofovir disoproxil fumarate is available as film coated tablets consisting of 600mg of Efavirenz, 200mg of Emtricitabine and 300mg of Tenofovir disoproxil fumarate. The usual recommended dosage of this combination regimen is one tablet every day, preferably at bedtime.

Warnings, Precautions and Side Effects of undefined

Warnings

Do not take this medication if you have experienced hypersensitivity reactions to Efavirenz, Emtricitabine or Tenofovir disoproxil fumarate. Patients who are diagnosed with pancreatitis or at risk of pancreatitis should take this combination medicine with caution. During the Efavirenz, Emtricitabine and Tenofovir disoproxil Fumarate Tablet treatment, your doctor may periodically monitor your blood counts, bone mineral density, liver and kidney parameters to prevent serious complications. Report to your doctor if you have had a history of heart failure, seizures, pancreatitis, bone disease, fractures, mental illnesses, liver or kidney problems. Seek immediate medical attention from a nearby hospital if you experience any psychiatric symptoms like depression or suicidal thoughts during this treatment.

Precautions

Adults of childbearing potential should consider using an effective contraceptive to prevent unwanted pregnancy. Avoid getting pregnant during and 12 weeks after the last dose of Efavirenz, Emtricitabine and Tenofovir disoproxil Fumarate. If you are pregnant or think you might be pregnant, your physician might suggest an alternative treatment as this combination regimen is not recommended during early pregnancy. Breastfeeding is not recommended due to potential transmission of HIV from mother to the baby.

Side Effects

The common side effects that are likely to occur while you are on the treatment with Efavirenz, Emtricitabine and Tenofovir disoproxil Fumarate Tablet are diarrhoea dizziness, impaired concentration, headache, nausea, vomiting, weakness, muscle pain, tiredness, rash, pain, depression, and electrolyte imbalance. Other possible side effects include high body fat and dark spots or freckles on skin. Some serious adverse reactions include bone loss, pancreatitis, worsening of Hepatitis B, acute kidney injury, immune reconstitution syndrome, etc. If you experience any allergic reactions after taking this tablet, report to your doctor immediately.

Word Of Advice

Efavirenz, Emtricitabine and Tenofovir disoproxil Fumarate can make you feel tired and dizzy. Hence, you should avoid driving or handling machines during this treatment

Frequently Asked Question

• What should you not take with Efavirenz, Emtricitabine and tenofovir disoproxil fumarate?
• It is not recommended to take Efavirenz, Emtricitabine and tenofovir disoproxil fumarate tablet with other HIV medications. Tell your healthcare provider if you are taking any other medications, over-the counter drugs, vitamin or herbal supplements.

• How to store Efavirenz, Emtricitabine and Tenofovir disoproxil Fumarate Tablets?
• Store Efavirenz, Emtricitabine and Tenofovir disoproxil Fumarate Tablets between 20-25°C in its original container, away from the reach of children.

• What should you do if you miss a dose of Efavirenz, Emtricitabine and Tenofovir disoproxil Fumarate Tablet?
• If you missed a dose of Efavirenz, Emtricitabine and Tenofovir disoproxil Fumarate Tablet, take one tablet as soon as you remember. However, if it is almost time for your next dose, skip this dose and take your next dose as per schedule. 

• What are the required laboratory parameters prior to starting this treatment?
• If you are an adolescent or adult of childbearing potential, your healthcare provider will perform pregnancy test before prescribing this treatment. Other prominent tests include test for HBV infection, blood cholesterol, blood glucose, serum creatinine, estimated creatinine clearance, liver parameters and urine protein.

• What other precautions should you follow during HIV treatment?
• It is advisable to avoid sharing needles and personal items like toothbrush and razors with others. Always follow safe sexual practices by using protection. Do not stop taking HIV medications without telling your doctor.

• What are some of the long-term side effects of this combination regimen?
• Some serious side effects of this combination regimen include worsening of hepatitis B, bone loss, acute kidney injury, pancreatitis, immune reconstitution syndrome, liver toxicity lactic acidosis and hypersensitivity reactions.

• Why should you take Efavirenz, Emtricitabine and Tenofovir disoproxil fumarate tablet on an empty stomach?
• Efavirenz, Emtricitabine and Tenofovir disoproxil fumarate should be taken on an empty stomach, preferably at bedtime to minimize the risk of side effects.