Uses of undefined

Efavirenz, Lamivudine and Tenofovir disoproxil Fumarate is indicated as a complete regimen to treat human immunodeficiency virus infection in adults and paediatric patients weighing at least 40kg.

undefined Drug administaration and Dosage available

Efavirenz, Lamivudine and Tenofovir disoproxil fumarate is available as film coated tablets consisting of 600mg of Efavirenz, 300mg of Lamivudine and 300mg of Tenofovir disoproxil fumarate. The usual recommended dosage of this combination regimen is one tablet every day, preferably at bedtime.

Warnings, Precautions and Side Effects of undefined

Warnings

Do not take this medication if you have experienced hypersensitivity reactions to Efavirenz, lamivudine or Tenofovir disoproxil fumarate. Patients who are diagnosed with pancreatitis or at risk of pancreatitis should take this combination medicine with caution. During the Efavirenz, Lamivudine and Tenofovir disoproxil Fumarate Tablet treatment, your doctor may periodically monitor your blood counts, bone mineral density, liver and kidney parameters to prevent serious complications. Report to your doctor if you have had a history of heart failure, seizures, pancreatitis, bone disease, fractures, liver or kidney problems. Seek immediate medical attention from a nearby hospital if you experience any psychiatric symptoms like depression or suicidal thoughts during this treatment.

Precautions

Adults of childbearing potential should consider using an effective contraceptive to prevent unwanted pregnancy. Avoid getting pregnant during and 12 weeks after the last dose of Efavirenz, Lamivudine and Tenofovir disoproxil Fumarate. If you are pregnant or think you might be pregnant, your physician might suggest an alternative treatment as this combination regimen is not recommended during early pregnancy. Breastfeeding is not recommended due to potential transmission of HIV from mother to the baby.

Side Effects

The common side effects that are likely to occur while you are on the treatment with Efavirenz, Lamivudine and Tenofovir disoproxil Fumarate Tablet are impaired concentration, abnormal dreams, headache, nausea, muscle pain, tiredness, diarrhoea, rash, dizziness, insomnia, pain, depression, asthenia and cough. Some serious adverse reactions include bone loss, worsening of Hepatitis B, acute kidney injury, immune reconstitution syndrome, etc. If you experience any allergic reactions after taking this tablet, report to your doctor immediately.

Word Of Advice

Efavirenz, Lamivudine and Tenofovir disoproxil Fumarate can make you feel tired and dizzy. Hence, you should avoid driving or handling machines during this treatment. 

Frequently Asked Question

• What should you not take with Efavirenz, lamivudine and tenofovir disoproxil fumarate?
• It is not recommended to take Efavirenz, lamivudine and tenofovir disoproxil fumarate tablet with other HIV medications. Tell your healthcare provider if you are taking any other medications, over-the counter drugs, vitamin or herbal supplements.

• How to store Efavirenz, Lamivudine and Tenofovir disoproxil Fumarate Tablets?
• Store Efavirenz, Lamivudine and Tenofovir disoproxil Fumarate Tablets below 30°C in its original container, away from the reach of children.

• What should you do if you miss a dose of Efavirenz, Lamivudine and Tenofovir disoproxil Fumarate Tablet?
• If you missed a dose of Efavirenz, Lamivudine and Tenofovir disoproxil Fumarate Tablet, take one tablet as soon as you remember. However, if it is almost time for your next dose, skip this dose and take your next dose as per schedule. Do not take two doses to compensate for the missed dose.

• What are the required laboratory parameters prior to starting this treatment?
• If you are an adolescent or adult of childbearing potential, your healthcare provider will perform pregnancy test before prescribing this treatment. Other prominent tests include test for HBV infection, blood cholesterol, blood glucose, serum creatinine, estimated creatinine clearance, liver parameters and urine protein.

• How do you know if you are hypersensitive to Efavirenz, Lamivudine or Tenofovir disoproxil fumarate?
• Watch out for symptoms like severe rash, Steven’s Johnsons syndrome, swelling of face or lips and reach out to your healthcare provider immediately if you experience any of these symptoms.

• What are some of the long-term side effects of this combination regimen?
• Some serious side effects of this combination regimen include worsening of hepatitis B, bone loss, acute kidney injury, pancreatitis, immune reconstitution syndrome, liver toxicity and hypersensitivity reactions.

• What are the psychiatric symptoms associated with the use of Efavirenz, Lamivudine or Tenofovir disoproxil fumarate?
• Feelings of sadness, hopelessness, anxiety, restlessness, trust issues, seeing or hearing things that are not real, inability to move or speak normally and thoughts about hurting self are some of the most prominent psychiatric symptoms associated with the use of Efavirenz, Lamivudine or Tenofovir disoproxil fumarate.