Uses of undefined

By facilitating the clotting process, Factor VIII helps prevent and control bleeding episodes in individuals with hemophilia A and other conditions associated with low factor VIII levels. It reduces the chance of complications such as bleeding, excessive blood loss, and related health issues

undefined Drug administaration and Dosage available

Factor VIII is usually administered through a vein (intravenously) by your physician in a hospital setting. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. Do not self-administer this injection.

Warnings, Precautions and Side Effects of undefined

Warnings

The use of this drug increases the cardiovascular risk. It is highly advised to discuss with your physician if you have any existing heart disease condition before initiating the treatment with Factor VIII. A central venous access device (CVAD) may sometimes be required to administer this drug treatment. It's important to consider the risks associated with CVAD-related complications, including local infections, bacteremia (bacterial infection in the bloodstream), and catheter site thrombosis (blood clot formation at the catheter site). Proper care and monitoring should be exercised to minimize these risks. The development of inhibitors (antibodies) is a known complication that can occur during treatment with this medicine. These inhibitors can interfere with the effectiveness of the treatment. Patients receiving Factor VIII therapy should be closely monitored for the development of inhibitors. If bleeding is uncontrolled with this drug, you must notify your doctor immediately.

Precautions

If you regularly or repeatedly receive human plasma-derived Factor VIII products, your doctor may recommend vaccination against hepatitis A and B. It is because there is a possible risk of exposure to these viruses through plasma-derived products. Vaccination can help protect against these infections. This drug is contraindicated in individuals with known hypersensitivity or allergy to it or its component. Stop taking this tablet and contact your doctor immediately if you develop a rash or skin symptoms. Inform your doctor of any heart, thyroid, kidney, or liver disease. Your physician may prescribe you a low dose and perform regular blood tests. If you are pregnant or breastfeeding, consult your doctor for more advice before starting the treatment with Factor VIII.

Side Effects

The side effects known to occur commonly during the treatment with Factor VIII are reddening of the skin, burning and stinging at the injection site, chills, flushing, headache, hives, hypotension, lethargy, nausea, restlessness, tachycardia, tightness of the chest, tingling, vomiting and wheezing.

Word Of Advice

Good dental hygiene is important to maintain oral health and prevent tooth and gum disease. It is particularly relevant for individuals with bleeding disorders such as hemophilia A, as they may be more susceptible to excessive bleeding. If you notice any changes in your symptoms or have concerns about the treatment with Factor VIII, immediately communicate them to your physician for more advice.

Frequently Asked Question

• Is Factor VIII derived from human plasma or produced through recombinant DNA technology?
• Factor VIII is available in both forms. It can be derived from human plasma, which undergoes a purification process or is produced using recombinant DNA technology. Both forms are effective in providing the necessary Factor VIII for treatment.

• Can Factor VIII be used in children?
• Yes, Factor VIII can be used in children. The dosage and administration may vary based on the child's age, weight, and needs. Pediatric patients with hemophilia A can benefit from regular treatment with Factor VIII to prevent and manage bleeding episodes.

• Are there any potential side effects of Factor VIII?
• The most common side effect of Factor VIII is the development of inhibitors (antibodies) that can interfere with the effectiveness of the treatment. Other possible side effects include allergic reactions, infusion site reactions, and the risk of blood clots.

• How is Factor VIII administered?
• Factor VIII is administered intravenously (IV) through a needle inserted into a vein by your physician in a hospital setting. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. 

• Can Factor VIII be used during surgery or dental procedures?
• Factor VIII can be used before surgery or dental procedures in individuals with hemophilia A to prevent excessive bleeding. Coordinating with the healthcare team is important to ensure proper dosing and timing.