This page contains brief details about the drug , it's indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Background and Date of Approval
Glutathione is an anti-oxidant, anti-melanogen, anti-aging, anti-fungal, anti-inflammatory, anti-malignant, and anti-ageing substance. Melanil is a fungal substance that is produced by Acetobacter (Acetobacter) and Aspergillus (Aspergillus) fungal species. It is also found in Penicillium. Melanin is a pigment that is naturally produced in the body. It is responsible for the color of the eyes, hair, and skin. It is necessary for tyrosine, an amino acid, to produce melanin. Kojic acid blocks tyrosine, which prevents melanin production. A decrease in melanin production may lighten the skin. Besides skin-lightening, glutathione also reduces inflammation and pain and protects the skin from light.
Mechanism of Action of undefined
Glutathione is a natural substance produced by the liver, which plays a significant role in protecting the cells from oxidative damage. It consists of amino acids glutamine, cysteine and glycine. It inhibits the action of enzymes that produce melanin. Kojic acid is a natural metabolic product synthesized by fungi. It has anti-inflammatory and antiproliferative properties that hinders melanin production by inhibiting the activity of an enzyme called tyrosinase. It also guards the skin from harmful UV rays. Glutathione + Kojic acid supplementation helps in protecting the cells and tissues from damage and reduces oxidative stress.
Uses of undefined
Glutathione + Kojic acid cream has been developed to reduce pain and inflammation and improve overall skin health. It is an antioxidant and antimelanogenic that helps treat ageing skin by reducing the production of melanin. It effectively treats various skin problems like hyperpigmentation, freckles, melasma, fine lines, wrinkles, bacterial and viral skin infections and also protects the skin from UVA and UVB rays of the sun.
undefined Drug administaration and Dosage available
Glutathione + Kojic acid is available in the form of 15ml Cream. Clean and dry the affected part of your skin and apply a thin film of the cream until you see desired results. Avoid contact with eyes.
Warnings, Precautions and Side Effects of undefined
Warnings
Contact your doctor immediately if you experience symptoms of skin allergies. Report to your doctor if you have had a history of any other medical conditions.
Precautions
It is not known if Glutathione + Kojic acid interferes with pregnancy or breastfeeding. Hence, it is advisable to tell your healthcare provider if you are pregnant, think you could be pregnant, breastfeeding or planning to have a baby.
Side Effects
Glutathione + Kojic acid does not lead to any prominent side effects and is generally safe to use. However, if you experience any undesirable effects like irritation and inflammation while using this product, report to your healthcare provider immediately.
Word Of Advice
Glutathione + Kojic acid is not known to interfere with your ability to drive or handle machines. Use this product exactly as prescribed by your healthcare provider to achieve desirable results
Frequently Asked Question
References
- Sinee Weschawalit et al., Glutathione and its antiaging and antimelanogenic effects, Clin Cosmet Investig Dermatol. 2017; 10: 147–153, [Accessed on 5th May 2023], https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5413479/pdf/ccid-10-147.pdf
- Sonthalia S, Daulatabad D, Sarkar R. Glutathione as a skin whitening agent: Facts, myths, evidence and controversies. Indian J Dermatol Venereol Leprol 2016, 82, 262-272, [Accessed on 5th May 2023], https://ijdvl.com/glutathione-as-a-skin-whitening-agent-facts-myths-evidence-and-controversies/
- Rashmi Sarkar, Pooja Arora and K Vijay Garg, Cosmeceuticals for Hyperpigmentation: What is Available?, J Cutan Aesthet Surg., 2013, 6(1), 4–11, [Accessed on 5th May 2023], https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3663177/
- Rochelle C Monteiro, et al., A Comparative Study of the Efficacy of 4% Hydroquinone vs 0.75% Kojic Acid Cream in the Treatment of Facial Melasma, Indian Journal of Dermatology, 2013, 58(2): 157, [Accessed on 5th May 2023], https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3657227/
- Saeedi M, Eslamifar M, Khezri K, Kojic acid applications in cosmetic and pharmaceutical preparations, Biomedicine & pharmacotherapy, 2018, 110, 582-593, [Accessed on 5th May 2023], https://reader.elsevier.com/reader/sd/pii/S0753332218367477?token=21F716647C2CB20DCD2568D464C1AFF176748895219BF23F983152695639A06D238F12C65407440EFFE15427DF42C349&originRegion=eu-west-1&originCreation=20210618092518
Disclaimer
The drug information on this page is not a substitute for medical advice, it is meant for educational purposes only. For further details consult your doctor about your medical condition to know if you are eligible to receive this treatment.
