Uses of undefined

Inclisiran  is used to lower  high cholesterol levels in your blood (primary hypercholesterolaemia, including heterozygous familial and non-familial, or mixed dyslipidemia)  together with a statin or a cholesterol-lowering diet.

undefined Drug administaration and Dosage available

Inclisiran will be administered to you by a healthcare professional in a hospital setting.  It is usually administered as a subcutaneous injection into the abdomen, upper arm, or thigh. Your doctor will decide the dose, route of administration, and frequency based on your disease condition and other factors. The second dose is given after 3 months and the subsequent dose every 6 months. It is available in the dose of 284mg.

Warnings, Precautions and Side Effects of undefined

Warnings

It is not recommended to use this medication if you are allergic to the active compound Inclisiran or its components. It is not recommended to use during pregnancy and breastfeeding, it is advised to consult your physician regarding further queries. It is not recommended for use in children and adolescents below 18 years.

Precautions

You should be taking a statin and following a diet to reduce your cholesterol before beginning this therapy. For the duration that you are receiving inclisiran, you should continue taking the statin and adhering to this cholesterol-lowering diet. Do not stop taking this medicine without consulting your doctor. Talk to your doctor if you have kidney disorders, breathing problems, liver disorders, heart problems, intolerance to sugars before taking this medicine. Inform your physician or pharmacist of any additional medications you are taking, have recently taken, or may take, including over-the-counter medications and herbal remedies.

Side Effects

The common side effects that are likely to occur while you are on the treatment with Inclisiran Injection are injection site reactions like redness, rash and pain, arthralgia, bronchitis, fever, chills and headache . If you experience any allergic reactions and serious adverse reactions, report to your doctor immediately.

Word Of Advice

It is advised to adopt heart-healthy lifestyle practices, such as eating a balanced diet low in saturated and trans fats, exercising frequently, keeping a healthy weight, and quitting smoking, in addition to taking inclisiran. It is advised not to stop your regular statin medications and follow proper diet since inclisiran is only effective along with these two therapies. It is not recommended to discontinue the drug without the advice of a healthcare professional even if your symptoms improve.  Follow your doctor's advice and routinely check your cholesterol levels. This facilitates monitoring inclisiran's efficacy and enables prompt modification of your treatment regimen, if necessary. If a dose is missed for more than three months, a new dosing regimen needs to be initiated. 

Frequently Asked Question

• Can Inclisiran be used during pregnancy or breastfeeding?
• The safety of Inclisiran during pregnancy and breastfeeding has not been established. It is important to consult with a healthcare provider before using Inclisiran if you are pregnant, planning to become pregnant, or breastfeeding.

• How often do I need to have my cholesterol levels checked while taking Inclisiran?
• Your healthcare provider will determine how often you need to have your cholesterol levels checked based on your individual health status and treatment response. Regular monitoring of cholesterol levels is typically recommended during Inclisiran therapy.

• Can I stop taking my other cholesterol-lowering medications if I start Inclisiran?
• It is important to follow your healthcare provider's instructions regarding the use of other cholesterol-lowering medications while taking Inclisiran. Inclisiran may be used in addition to other medications to achieve optimal cholesterol control.

• What should I do if I miss a dose of Inclisiran?
• If you miss a dose of Inclisiran, contact your healthcare provider to reschedule the missed dose. Usually inclisiran is given at an interval of 3 months. It is important to maintain the prescribed dosing schedule to ensure the effectiveness of Inclisiran therapy in lowering LDL cholesterol levels.

• What are the common side effects of Inclisiran?
• Common side effects of Inclisiran may include injection site reactions (such as pain, redness, or swelling), flu-like symptoms (such as fever, chills, or body aches), and headache. These side effects are usually mild and temporary.