Uses of undefined

Lenvatinib is a medication that is used to treat several types of cancer, including thyroid, liver, and kidney cancer. In patients with radioactive iodine-refractory differentiated thyroid cancer, it can be used to slow the progression of the disease and reduce tumor size. It is also approved for the treatment of unresectable hepatocellular carcinoma (HCC), which is the most common type of liver cancer.

undefined Drug administaration and Dosage available

Lenvatinib is an oral medication that is usually taken once a day, at approximately the same time each day, with or without food. It should be taken as prescribed by a doctor or other healthcare provider. These capsules should be swallowed whole with a glass of water. They should not be crushed, chewed, or opened, as this can affect the way the medication is absorbed and decrease its effectiveness. You should not take a double dose to make up the second dose.

Warnings, Precautions and Side Effects of undefined

Warnings

Lenvatinib can cause an increase in blood pressure and increase the risk of heart attack, stroke, and other cardiovascular events. This medication can increase the risk of bleeding or hemorrhage and impair wound healing. It can cause kidney damage or kidney failure which results in proteinuria (an abnormal amount of protein in the urine). Sometimes it can cause hypothyroidism or other thyroid dysfunction. In rare cases, this medication can cause a condition called reversible posterior leukoencephalopathy syndrome (RPLS), which can cause seizures, confusion, and other neurological symptoms.

Precautions

Patients taking lenvatinib should monitor their blood pressure regularly, and if hypertension is not well-controlled, the dose needs to be adjusted or treatment may need to be stopped. Patients with a history of cardiovascular disease, history of bleeding, or taking blood thinners require close monitoring. Patients should inform their healthcare provider if they plan to have any surgical procedures during treatment as this medication increases the risk of bleeding. You should do urine tests regularly for protein checks and any signs of kidney problems while taking this medication. Women of reproductive age should use effective contraception while taking it and for at least one week after the last dose. You should do thyroid function testing regularly while taking and if there are signs of thyroid dysfunction tell your doctor immediately.

Side Effects

Lenvatinib can cause several side effects, some of which can be serious. Common side effects include fatigue, decreased appetite, weight loss, muscle pain, nausea, vomiting, and diarrhea. Patients may also experience high blood pressure. Other potential side effects include liver damage, blood clotting problems, and heart problems. Patients should be monitored closely for signs of liver damage, such as yellowing of the skin or eyes, dark urine, or abdominal pain. It can also increase the risk of blood clots, which can be life-threatening. This medication can cause serious heart problems, including heart attack, stroke, and heart failure.

Word Of Advice

If you are receiving close communication with your healthcare provider and report any concerns or side effects as soon as possible. Avoid getting pregnant and breastfeeding during treatment. Patients should avoid eating grapefruits as they affect the absorption of this drug. Patients should use sunscreen and wear protective clothing while outdoors to reduce the risk of sunburn or skin damage. You should avoid strenuous activities or exercise until you know how this medication is affecting you. Maintain a healthy and balanced diet during treatment to support your overall health and well-being. By being informed and engaged in your treatment, you can help ensure the best possible outcomes and manage any potential risks or complications associated.

Frequently Asked Question

• Can lenvatinib cause infertility?
• Lenvatinib can cause changes in menstrual periods and may affect fertility in some women. Patients should discuss their fertility concerns with their healthcare provider before starting this medication.

• Can lenvatinib cause hair loss?
• Yes, hair loss is a potential side effect of lenvatinib. However, not all patients experience hair loss while taking this medication. Patients should discuss the potential side effects with their healthcare provider before starting treatment.

• Can lenvatinib cause heart problems?
• Lenvatinib can cause high blood pressure, which may increase the risk of heart problems. Patients should have their blood pressure monitored regularly while taking this medication.

• Can I go for a teeth extraction if I am taking Lenvatinib?
• Before undergoing any dental procedures, it's important to inform your dentist and healthcare provider that you are taking lenvatinib. It can increase the risk of bleeding, and dental procedures that involve cutting or removing tissue may increase this risk further. Your healthcare provider and the dentist may recommend taking certain precautions, such as temporarily stopping of this medication before the procedure or adjusting your medication dose.

• Can lenvatinib cause vision problems?
• Yes, vision problems are a potential side effect of lenvatinib. Patients should report any changes in vision to their healthcare provider immediately.

• Can lenvatinib be used in children?
• Lenvatinib is not currently approved for use in children. The safety and efficacy in children have not been established.