Uses of undefined

Lorlatinib Tablet has been developed to treat adults with Non-small cell lung cancer (NSCLC) that resulted due to mutation in Anaplastic Lymphoma Kinase and ROS-1 genes and has spread to other parts of the body.

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Your doctor will decide the dose and duration of Lorlatinib based on the disease condition and other factors. Take the tablet at the same time everyday, with or without food. Do not chew, crush, or break the tablet. Swallow the whole tablet with water. If you forgot to take the tablet, simply take your next dose at the scheduled time. Do not take a double dose to make up for a forgotten dose.

Warnings, Precautions and Side Effects of undefined

Warnings

Tell your Healthcare provider before starting this treatment if you have kidney problem, breathing trouble, seizures, depression, diabetes, heart problems or high blood pressure. During the Lorlatinib Tablet treatment, your doctor may periodically monitor your blood pressure, blood sugar, liver, cholesterol and kidney parameters to prevent serious complications. Report to your doctor if you have had a history of heart failure, depressive episodes or seizures. Get immediate medical attention if you are feeling very thirsty, sick, weak or tired.

Precautions

Lorlatinib Tablet may decrease fertility in males which could affect your ability to father a child. Male patients with female sexual partners should use an effective contraceptive during this treatment and continue for at least three months after the last dose of Lorlatinib. It is recommended for female patients to do a pregnancy test before beginning this treatment as Lorlatinib is not recommended for use during pregnancy. Discuss effective non hormonal contraceptive methods with your health care provider and use them during this treatment and continue for at least six months after the last dose.

Side Effects

The common side effects that are likely to occur while you are on the treatment with Lorlatinib Tablet are swelling of arms, legs, hands and feet, numbness and tingling, weight gain, forgetfulness, confusion, tiredness, breathing difficulty, joint pain, diarrhoea, depression, irritability, high cholesterol and triglyceride levels, cough. If you experience any adverse reactions such as breathlessness, hallucination or suicidal thoughts, report to your doctor immediately

Word Of Advice

Lorlatinib Tablet might cause breathing difficulty and problems with thinking. Hence it is advisable to avoid driving or operating machines during this treatment. Tell your Healthcare provider before starting this treatment if you are taking any prescription medicines, over the counter medicines, vitamins or herbal supplements.

Frequently Asked Question

• Can I drink alcohol while taking Lorlatinib?
• It is generally recommended to avoid drinking alcohol while taking Lorlatinib, as alcohol can increase the risk of liver damage.

• What should you know before taking Lorlatinib tablets?
• Lorlatinib tablets can alter cholesterol and triglyceride levels in the blood, slow down heart rate, increase your blood pressure and glucose levels. Hence, your health care provider will monitor your symptoms and blood parameters before and during this treatment.

• Is it safe for women of reproductive age to use Lorlatinib Tablet?
• While for women with reproductive potential subjected to Lorlatinib Tablet, it is advisable to discuss with your doctor the effective birth control methods (non-hormonal) during the treatment. Also, it is essential to continue birth control treatment for a minimum of 6 months after the last dose, as this medicine may impair fertility.

• What should you do if you miss a dose of Lorlatinib Tablet?
• If you miss a dose of Lorlatinib Tablet, take it as soon as you remember. However, if your next dose is due within 4 hours, skip this dose and take your next dose at your regular time. Do not take 2 doses to make up for your missed dose.

• What are the side effects of Lorlatinib Tablet?
• The common side effects that are likely to occur while you are on the treatment with Lorlatinib Tablet are Swelling of arms, legs, hands and feet, numbness and tingling, weight gain, forgetfulness, confusion, tiredness, breathing difficulty, joint pain, diarrhoea, depression, irritability, high cholesterol and triglyceride levels, cough.

• When should you contact your physician?
• Reach out to your physician right away if you experience problems with thinking like forgetfulness or confusion, seeing or hearing things that are not real, depression, suicidal thoughts, seizures, changes in speech or sleep pattern.