This page contains brief details about the drug , it's indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Background and Date of Approval

N-Acetylcysteine is a mucolytic drug developed by the U.S. Food And Drug Administration and initially approved for treating chronic bronchitis.

Mechanism of Action of undefined

N-Acetylcysteine works by replenishing the levels of glutathione, a naturally occurring antioxidant in the body. It helps protect cells from damage caused by oxidative stress and can break down thick mucus, making it easier to clear from the airways.

Uses of undefined

N-Acetylcysteine is used to thin and loosen mucus in the airways, making it easier to clear. This is particularly beneficial in respiratory conditions such as chronic obstructive pulmonary disease (COPD), cystic fibrosis, and reduces the symptoms of chronic bronchitis. Some individuals take it for its potent antioxidant effects. It also plays a major role as a life-saving antidote for treating acetaminophen overdose, which can cause severe liver damage if not properly addressed.

undefined Drug administaration and Dosage available

Take the N-Acetylcysteine as advised by your physician. Do not crush, chew, or open the medicine. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. Only stop taking the tablet if your doctor advises you to stop.

Warnings, Precautions and Side Effects of undefined

Warnings

If you are allergic to this drug or any of its ingredients, do not use it. Individuals who suffer from bronchial asthma, duodenal ulcers, or a history of kidney or liver issues should use this drug cautiously, and dosage adjustments may be necessary. Be cautious if you have histamine intolerance.

Precautions

Prolonged treatment with this drug may influence histamine metabolism and lead to intolerance symptoms, such as headaches, runny nose, or itching. Limited information is available about using this during pregnancy and breastfeeding. Consult your doctor before starting the treatment with N-Acetylcysteine.

Side Effects

The side effects known to occur commonly during the treatment with N-Acetylcysteine are abdominal pain, headache, dizziness, inflammation of the oral mucous lining, impaired digestion, and confusion. Some serious side effects include allergic reactions, blistering, peeling, bleeding, or scaling of the skin.

Word Of Advice

This drug can be taken with or without food. If it upsets your stomach, taking it with a meal may help minimize gastrointestinal discomfort. Drink plenty of water while using the drug to help prevent dehydration, especially if you are experiencing respiratory issues. Take N-Acetylcysteine consistently at the same times each day to maintain steady levels in your body.

Frequently Asked Question

References

  1. Hermes Pharma Gmbh, Electronic medicines compendium (EMC), [Revised on May 2022] [ Accessed on 4th Sep 2023], https://www.medicines.org.uk/emc/files/pil.13849.pdf
  2. Anna M Sadowska et al., Role of N-Acetylcysteine in the management of COPD, [Published on 2006] [Accessed on 4th Sep 2023], https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2707813/
  3. C Stey et al., The effect of oral N-Acetylcysteine in chronic bronchitis: A quantitative systematic review, [Published on 2000] [Accessed on 4th Sep 2023], https://pubmed.ncbi.nlm.nih.gov/10968500/

Disclaimer

The drug information on this page is not a substitute for medical advice; it is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you are eligible to receive this treatment.