This page contains brief details about the drug , it's indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Background and Date of Approval

Potassium magnesium citrate is approved by the FDA for treating low potassium levels in the blood, a condition known as hypokalemia. This medication can be used to treat magnesium deficiency, which can occur due to poor dietary intake, certain medications, or certain health conditions that may interfere with magnesium absorption or increase magnesium excretion. It may also be used to help prevent the formation of certain types of kidney stones, such as calcium oxalate stones.

Mechanism of Action of undefined

Potassium magnesium citrate works by replenishing potassium and magnesium levels in the body, crucial for maintaining muscle and nerve function, regulating heart rhythm, and supporting bone health. The citrate component aids in preventing the formation of certain kidney stones by binding to urinary calcium and promoting the breakdown of existing stones. Together, these actions make this medication an effective solution for addressing mineral deficiencies and reducing the risk of specific kidney stones.

Uses of undefined

Potassium magnesium citrate is used for the treatment of hypokalemia, management of magnesium deficiency, prevention of kidney stones and potassium deficiency.

undefined Drug administaration and Dosage available

Potassium magnesium citrate is available in two dosage forms, tablets at 978 mg and sachets at 5 mg respectively. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. 

Warnings, Precautions and Side Effects of undefined

Warnings

It is not recommended to take this medication if you are allergic to the active substance potassium magnesium citrate and its components. This medication should be avoided by individuals with high levels of potassium in the blood (hyperkalemia). Taking additional potassium in such cases can further increase the risk of serious complications, such as irregular heartbeats or cardiac arrest. It is crucial to regularly check electrolyte levels, particularly magnesium and potassium, especially in people who are at risk of electrolyte imbalances or have kidney issues.

Precautions

Before taking potassium magnesium citrate supplements, women who are pregnant or nursing should speak with their healthcare professional as the safety of these supplements may not be well established at these times. Individuals with severe kidney impairment or those with a history of kidney disease may need to avoid or use. Dehydrated individuals should use this medication cautiously, as dehydration can affect kidney function and the body's ability to regulate potassium and magnesium levels. Furthermore, avoid using machinery or driving while receiving therapy if you feel lightheaded, and consult your doctor right away. It is really important to be safe, so make sure you discuss any concerns you may have with your healthcare professional.

Side Effects

Like any other drug, potassium magnesium citrate also has some side effects. The most common side effects people may experience are gastrointestinal disturbances, upset stomach, diarrhea. Patients may also experience serious side effects such as hyperkalemia, magnesium toxicity, allergic reactions. Keep an eye out for these signs and contact your doctor immediately if you experience any of them while receiving therapy.

Word Of Advice

Individuals with impaired kidney function should exercise caution, as the Potassium magnesium citrate can affect electrolyte balance, particularly potassium and magnesium levels, which are excreted through the kidneys. Regular monitoring of kidney function and electrolyte levels is crucial in such cases. Moreover, individuals with pre-existing cardiovascular conditions should use this medication with care, as fluctuations in potassium levels may impact heart function. Those with a history of allergic reactions to any of the components of this medication should consult a healthcare professional before use. Additionally, it is important to discuss all current medications and adhere to the prescribed dosage to prevent potential interactions and side effects associated with excessive intake of potassium and magnesium. 

Frequently Asked Question

References

  1. Thornton & Ross Ltd, Electronic Medicines Compendium (EMC),[Revised on 09 Nov 2020][ Assessed on 2nd Nov 2023], https://www.medicines.org.uk/emc/product/4922/smpc
  2. Joseph E Zerwekh et al; Reduction of renal stone risk by potassium-magnesium citrate during 5 weeks of bed rest; The Journal of Urology; [Published on June 2007] [Accessed on 2nd Nov 2023] https://pubmed.ncbi.nlm.nih.gov/17509313/

Disclaimer

The drug information on this page is not a substitute for medical advice. It is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you can receive this treatment.