Uses of undefined

Ruxolitinib treats myelofibrosis, polycythemia vera, and graft versus host disease (GvHD).

undefined Drug administaration and Dosage available

Ruxolitinib is available as a tablet with 5mg, 10 mg, 15 mg, 20 mg, and 25 mg. The recommended dose of Ruxolitinib is based on platelet count. If the platelet count is greater than 200,000/mm3, the recommended dose is 20 mg twice daily. Take this medication with or without food. Avoid crushing or chewing instead of swallowing it whole.

Warnings, Precautions and Side Effects of undefined

Warnings

Inform your doctor immediately if you experience allergies (hypersensitive) with Ruxolitinib and its ingredients. If you have liver, kidney, or heart problems, report to your doctor. You might require routine blood tests while taking Ruxolitinib to monitor your blood counts. Tell your physician if you notice any signs of infection such as fever, sore throat, or rash or if you have or ever had skin cancer, tuberculosis, or infections before taking this medication.

Precautions

Consult your doctor before using Ruxolitinib if you are pregnant or plan to have a baby. Even though there are limited studies on humans, animal studies have shown harmful effects on the developing baby. Before prescribing them, your doctor will weigh the benefits and potential risks. Effective contraceptive methods used by men and women during treatment are recommended to avoid pregnancy. Avoid breastfeeding your baby while on this medication as it is unknown if Ruxolitinib passes into the breastmilk.

Side Effects

The common side effects that are likely to occur while you are on the treatment with Ruxolitinib are dizziness, headache, high cholesterol levels, weight gain, high blood pressure, difficulty in breathing, pain in the chest, constipation, flatulence, etc. If you experience skin rash with blisters, low blood cell count, fever, chills, or infections, report to your physician immediately.

Word Of Advice

Ruxolitinib is unsuitable for children and adolescents below 18. Regular blood tests are recommended to monitor your blood cells, liver and kidney function, and lipid levels during treatment with this medicine. If you have lactose intolerance, inform your doctor before starting this therapy. Driving or using machinery should be avoided if you feel tired or sleepy, which may impair your vision.

Frequently Asked Question

•  What is Ruxolitinib used for?
• Ruxolitinib treats myelofibrosis, polycythemia vera, and graft versus host disease (GvHD).

• What class of medication is Ruxolitinib?
• Ruxolitinib belongs to a group of medicines called Tyrosine kinase inhibitors. 

• What are the side effects of Ruxolitinib?
• The common side effects of Ruxolitinib include dizziness, headache, high cholesterol levels, weight gain, high blood pressure, difficulty breathing, pain in the chest, constipation, and flatulence.

• How does  Ruxolitinib work?
• Ruxolitinib works by preventing the abnormal growth and multiplication of blood cells by blocking the enzymes JAK1 and JAK2 (Janus Associated Kinases). It helps in stopping or reducing the spread of cancer cells.

• Is Ruxolitinib safe while driving?
• Ruxolitinib is unsafe while driving or handling machines since it may cause dizziness.

• Does Ruxolitinib cause fatigue?
• Ruxolitinib may cause fatigue due to anemia (low red blood cell counts). If this disturbs or persists for a long time, consult your doctor for advice.

• Can children use Ruxolitinib?
• Yes, Ruxolitinib can be used by children aged 12 and above.