This page contains brief details about the drug , it's indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Background and Date of Approval

Tadalafil + dapoxetine was approved for medical use to treat erectile dysfunction and premature ejaculation in men of the age group between 18 to 64 years.

Mechanism of Action of undefined

The combination medication tadalafil + dapoxetine helps men to obtain and sustain erections by relaxing blood vessels and increasing blood flow to the penis, significantly increasing the ejaculatory duration and enhancing ejaculatory control.

Uses of undefined

Tadalafil + dapoxetine helps people delay premature ejaculation and help them achieve and maintain good erections for sexual activities. An erection that is not strong enough for sexual engagement can be a result of erectile dysfunction. Men who ejaculate too soon and with minimal sexual arousal are said to be experiencing premature ejaculation.  It helps achieve a balanced sexual life in men.

undefined Drug administaration and Dosage available

Tadalafil + dapoxetine combination is available in tablet form containing tadalafil 10 mg and dapoxetine 30mg. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition.

Warnings, Precautions and Side Effects of undefined

Warnings

 Tadalafil + dapoxetine is not meant for use in women. Children and teenagers less than the age of eighteen should not use this medication. Avoid taking Tadalafil + dapoxetine if you are allergic to dapoxetine hydrochloride, tadalafil, or any of its components.

It is not recommended to use this medication if you have had a heart attack within the last three months, have low blood pressure, have mental health problems such as depression or mania, have a history of bleeding or blood clotting problems, or suffer from significant liver or renal impairment. Before beginning this treatment, tell your doctor about your condition and give them a thorough history of all your medications.

Precautions

Tadalafil + dapoxetine is only intended for treatment in men. It should not be given to women, therefore not suitable for pregnancy and breastfeeding. Inform your healthcare provider about any pre-existing lung diseases and severe liver conditions before starting the medication. Consuming alcohol is not advised due to its potential to affect both erection quality and induce dizziness. Furthermore, it is recommended to refrain from driving or operating heavy machinery due to the potential for dizziness and drowsiness. Always consult your doctor for personalised advice and guidance.

Side Effects

Tadalafil+Dapoxetine can cause side effects like any other medicine. Sometimes it may cause some serious side effects that include skin reactions (allergy, blisters), palpitations (increased heartbeats), priapism (prolonged erection), and commonly, people may experience dizziness, headache, blurred vision, nasal congestion, mood changes (irritable, anxious, agitated, or restless), nausea, vomiting, dry mouth.

Word Of Advice

It is recommended to drink at least one full glass of water with this medication to reduce the chance of fainting. Engaging in sexual activity can increase cardiac strain; if you get any symptoms, such as nausea, dizziness, or chest discomfort during intercourse, stop immediately and seek medical attention. If you experience prolonged and painful erections, immediate medical attention is necessary to prevent permanent erectile dysfunction. After taking the drug, if you feel dizzy, sit or lie down to avoid falling owing to low blood pressure. Consuming grapefruit juice for 24 hours before taking this medication is not recommended as it may increase the risk of medication toxicity.

Frequently Asked Question

References

  1. Cipla (EU) Limited, Electronic medicines compendium (EMC), [Revised on August 2021] [Accessed on Nov 2023] https://www.medicines.org.uk/emc/files/pil.10231.pdf 
  2. Menarini - Von Heyden GmbH, Electronic medicines compendium (EMC), [Revised on June 2021] [Accessed on Nov 2023] https://www.medicines.org.uk/emc/files/pil.1269.pdf 
  3. Eli Lilly and Company, Food and Drug Administration (FDA), [Revised on October 2011] [Accessed on Nov 2023] https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/021368s20s21lbl.pdf 
  4. KD Tripathi, Essentials of Medical Pharmacology, Androgens and Related Drugs, Drugs for Erectile Dysfunction, 8th edition, 2019, 328.

Disclaimer

 The drug information on this page is not a substitute for medical advice. It is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you can receive this treatment.