Uses of undefined

Treosulfant is an anti-neoplastic medication belonging to the group called alkylating agents. This medicine is combined with Fludarabine to treat allogeneic hemopoietic stem cell transplant (alloHSCT) in adults with both malignant and non-malignant. In pediatric patients (older than one month), it treats malignant. 

undefined Drug administaration and Dosage available

Treosulfan injection is administered as an intravenous infusion into the vein. If this injection is recommended for you, it will be given by a healthcare professional. Do not self-administer. Your physician will choose the dosage and administration frequency based on the medical condition because it differs for each person.

Warnings, Precautions and Side Effects of undefined

Warnings

Do not take a Treosulfan injection if you are allergic to Treosulfan or its other ingredients. Notify your doctor if you have any infections or disorders with the heart, lungs, liver, or kidney. Before starting the treatment, inform your doctor if you took any live vaccine or have Fanconi anemia (inherited bone marrow failure syndromes) or other DNA breakage repair disorders. 

Precautions

This medicine may reduce the blood count (myelosuppression); your doctor will monitor your blood counts and liver enzymes regularly to detect their functions until recovery of the hematopoietic system. Before taking a Treosulfan injection, notify your doctor if you are pregnant or planning to get pregnant or breastfeeding. In pediatric patients, dermatitis diaper (inflammation of the skin in the diaper area) may occur, so napkins should be changed frequently for 6–8 hours. Contact your doctor for more information. 

Side Effects

The most common side effects of Treosulfan are diarrhea, constipation, weight loss, poor appetite, nausea, vomiting, excessive growth of hair in the skin, low blood counts, difficulty breathing, cough, liver problems, infections, headache, weakness, and skin rash. 

Serious side effects while taking Treosulfan are decreased blood cell count, infections, liver vein blockage, and lung inflammation.

Word Of Advice

Store at 25˚C, excursions permitted to 15˚C to 30˚C. Keep away from pets and children. Do not refrigerate. This medicine can cause fertility impairment; consult your doctor for more fertility concerns. Don't splash or spill the medicine anywhere on the skin. In infants under four months, there is a chance of getting a seizure. Hence monitor for nervous disorders and breathing problems. 

Frequently Asked Question

• How is Treosulfan dosage determined? 
• Treosulfan dosage is based on several factors, including the type and stage of the cancer being treated, the individual's overall health, and their response to the treatment.

• Can Treosulfan cause a lower level of Bilirubin? 
• One of the common side effects of Treosulfan is the lower level of Bilirubin. If you experience any side, contact your physician immediately. 

• Why is liver enzyme getting elevated during treatment with Treosulfan? 
• The reason for this elevation is not completely understood, but it is thought to be related to the drug's effects on certain enzymes involved in liver function. The elevation in liver enzymes is generally mild and temporary and typically resolves on its own or with dose adjustment of the Treosulfan tablet. 

• What if I missed a dose of Treosulfan?
• Do not miss your dose. Keep all your appointments with the dosing regularly. If you forget or miss an appointment, inform your healthcare professional and reschedule the dosing.

• Can I stop taking Treosulfan after I feel better?
• Even if you feel better, continue taking doxycycline until the prescription is completed. If you stop using Treosulfan injections too soon or skip doses, your illness may not be entirely treated.