This page contains brief details about the drug , it's indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Background and Date of Approval
Vinorelbine is a chemotherapy medication that was approved to be used in 1994.
Mechanism of Action of undefined
Vinorelbine works by inhibiting the microtubule structures within the cell. Microtubule structures help cancer cells to divide and multiply. Inhibition of these structures slows the growth and multiplication of cancer cells.
Uses of undefined
- Non-small cell lung cancer (NSCLC)
- Breast cancer
undefined Drug administaration and Dosage available
Vinorelbine is available as solution for infusion in two doses of 10mg and 50mg.
Warnings, Precautions and Side Effects of undefined
Warnings
Before starting treatment with Vinorelbine inform your doctor if you have chest pain, had a heart attack and liver problems. If you have undergone radiation therapy including the liver, inform your doctor. Report to your doctor if you experience fever, chills, joint pain and cough as these may be the signs and symptoms of an infection. Inform your doctor about all the non-prescription medicines you have taken while being treated with Vinorelbine. If you plan on getting vaccinated or have undergone vaccination, then report it to your doctor before starting treatment with this medicine. Regular blood cell counts will be performed before and during treatment with Vinorelbine.
Precautions
Both men and women of child bearing age are advised to use effective contraceptive methods while being treated with Vinorelbine. Effective contraception is also to be taken for up to 3 months after the last dose of the medicine. Do not take this medicine if you are pregnant or think that you might be expecting. Contact your doctor immediately if you get pregnant while taking this medicine. Breastfeeding must not be done while taking Vinorelbine. In case a breast-feeding mother has to take this medication, then breast feeding is to be stopped. This medication may affect the ability to drive and use machines, hence it is recommended not to drive or use machines while being treated with this medication.
Side Effects
The common side effects that are likely to occur while you are on the treatment with Vinorelbine include, Nausea, vomiting, low blood cell counts, weakness, hair loss, swelling or sores in the throat or mouth, injection site reactions (redness, burning pain, vein discoloration), pain in the jaws, joints, and muscles, tiredness and diarrhea.
Word Of Advice
As this medicine can affect fertility, male patients should get advice on sperm conservation. Effective contraception is to be used by both men and women throughout the treatment Vinorelbine. Inform your doctor about nay medication or supplements you are taking before starting treatment with this medicine.
Frequently Asked Question
References
- Pierre Fabre Limited, Electronic medicines compendium (EMC), [Revised on Nov 2022] [ Accessed on 1st Dec 2022], https://www.medicines.org.uk/emc/files/pil.3912.pdf
- Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Cytotoxic agents, 12th edition, 2011, 1706.
- KD Tripathi, Essentials of Medical Pharmacology, Anticancer drugs, 7th edition, 2013, 865.
- Pierre Fabre Medicament, US Food and Drug administration, [Revised on Jan 2022] [ Accessed on 1st Dec 2022], https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/020388s037lbl.pdf
- Anna Capasso; Vinorelbine in Cancer therapy; Cancer Drug Targets; Published on July 2012; Accessed on 01/12/2022; https://pubmed.ncbi.nlm.nih.gov/22594474/
- Ying-Chun Xu et al; A systematic review of vinorelbine for the treatment of breast cancer; The Breast Journal; Published on April 2013; Accessed on 01/12/2022; https://pubmed.ncbi.nlm.nih.gov/23320984/
Disclaimer
The drug information on this page is not a substitute for medical advice; it is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you are eligible to receive this treatment.
