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Acriptega Tablet
Prescription Required
Salt Composition : Dolutegravir,lamivudine,tenofovir Disoproxil Fumarate
Manufacturer : MYLAN PHARMACEUTICALS PVT LTD
Origin of Medicine : India
30 Tablet(s) In A Bottle
Introduction to Acriptega Tablet
Acriptega tablet consists of the active substance called Dolutegravir, Lamivudine, Tenofovir disoproxil fumarate. Dolutegravir is an antiviral medicine belonging to the integrase inhibitor family. Lamivudine, Tenofovir disoproxil fumarate, which belongs to the antiretroviral medicine class. This medicine treats HIV (human immunodeficiency virus) infection in adults and children with 40kg or greater. It is a nucleotide reverse transcriptase inhibitor (NRTI) and works by inhibiting the enzymes (HIV reverse transcriptase), which is important for virus replication. While consuming this medicine, you may still develop infections related to HIV. Although effective antiretroviral therapy reduces the risk, HIV transmission is still possible when using this medication. Contact your doctor for more information.
Do not take Acriptega tablet if you are allergic to Dolutegravir, Lamivudine, Tenofovir Disoproxil Fumarate, or its other medical ingredients. Patients diagnosed with pancreatitis or at risk of pancreatitis should take this combination of medicine cautiously. During this treatment, your doctor may periodically monitor your blood counts, bone mineral density, liver and kidney parameters to prevent serious complications. Notify your doctor if you have or had a history of lactic acidosis (excess lactic acid), pancreatitis (inflammation in the pancreas), bone disease (osteonecrosis - the death of bone tissue), fractures, liver (chronic hepatitis B), or kidney problems.
Inform your doctor if you are planning to get pregnant or think you may be pregnant. Breastfeeding is not recommended while taking Acriptega tablet due to the potential transmission of HIV infection to the baby from mother.
Uses of Acriptega Tablet
- Human Immunodeficiency Virus 1 (HIV) infection in adults and children (40kg or greater).
Therapeutic Effects of Acriptega Tablet
Acriptega tablet lowers HIV by inhibiting its replication. It increases the number of CD4 (T) cells, enabling the immune system to fight other infections. This lowers the risk of severity and death associated with a weak immune system.
Interaction of Acriptega Tablet with other drugs
Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional and vitamin supplements, and herbal products. Certain medications interact with Efavirenz, Lamivudine, Tenofovir Disoproxil Fumarate and reduce their effectiveness by causing undesirable side effects.
More Information about Acriptega Tablet
- Store at 30°C.
- Protect the medicine from light and excessive moisture.
- Keep the drug out of reach of children and pets.
How to consume Acriptega Tablet
It is taken orally. Your doctor will decide the dose and duration of Acriptega based on the disease condition and other factors. Always take this medicine as prescribed by your doctor. Take the tablet at the same time. Do not take an additional dose to compensate for the missed dose. Do not chew, dissolve, crush, or break the tablet.
Safety Advices for Acriptega Tablet
Pregnancy
Notify your healthcare professional if you are pregnant or planning to have a baby think you may be pregnant. Your physician will conduct regular tests to monitor the development of your child. Ask for suggestions before taking the Acriptega tablet.
Breast Feeding
It is unsafe to breastfeed if you are with HIV infection. Consult your doctor for more information about Acriptega tablets.
Lungs
It is unknown whether Acriptega tablet is safe for patients with lung problems. Inform your physician if you have any lung disease before starting the treatment. Contact your doctor if you experience any lung-related symptoms.
Liver
Inform your physician about any underlying liver disorders before taking Acriptega tablet should be used cautiously in liver disease patients. Your doctor may monitor your liver enzymes. Consult your physician before taking this medicine.
Alcohol
Do not consume alcohol while taking the Acriptega tablet, as this injection may cause drowsiness with alcohol.
Driving
It is unsafe to drive while taking Acriptega tablet because this medicine might cause vision problems and tiredness, so avoid driving and operating machinery during this treatment.
Side Effects of Acriptega Tablet
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Serious:
- Rapid breathing
- Drowsiness
- Nausea, vomiting, and stomach pain
- Severe allergic reactions
- Severe mood disturbances, depression, and suicidal thoughts
- Confusion, forgetfulness, seizures, and tremor
- Liver toxicity (yellow skin, dark urine, light-colored skin)
- Kidney damage
Common:
- Bloating, flatulence
- Headache
- Sleeplessness
- Skin reactions
- Wheezing, swelling, or lightheadedness
- Hair loss
- Diarrhea
- Bone disorders
- Weakness
- Anemia
Word of Advice
Inform your doctor about your underlying infections. If you have advanced HIV (AIDS), you may develop signs of infection and inflammation or worsen the signs of an existing infection once treatment is started. Report your doctor for side effects. It is mandatory to tell your medical professional if you are consuming other medicines that may damage your kidneys. Always consume the dose recommended by your doctor. Acriptega tablet does not reduce the risk of transmitting HIV to others via sexual contact or blood contamination. You must continue the medication to avoid this complication. Always use effective contraception to have safe sex.
FAQs
Q 1. When should you report to your healthcare provider while taking Acriptega?
Reach out to your healthcare provider if you experience symptoms of hypersensitivity reactions or lactic acidosis and any other side effects. Also, reach out to your doctor if you have overdosed on the Acriptega tablet.
Q 2. Is Acriptega used to prevent HIV?
Yes, Acriptega is an antiretroviral medication to treat and manage HIV infection. It contains three active ingredients, Abacavir, Lamivudine, and Dolutegravir, which work together to inhibit the replication of HIV in the body. This medication is not typically used solely for prevention but rather for the treatment and suppression of HIV in individuals who are already diagnosed with the virus.
Q 3. Is that okay to refrigerate the Acriptega?
Store Dolutegravir, Lamivudine,Tenofovir disoproxil fumarate tablets below 30°C in its original container, away from the reach of children.
Q 4. What are the symptoms of lactic acidosis?
Unusual weakness, tiredness, muscle pain, trouble breathing, stomach pain, nausea, vomiting, dizziness, lightheadedness, irregular heartbeat, and feeling cold, especially in your legs and arms, are the most prominent symptoms of lactic acidosis.
Q 5. How can I manage side effects while taking Acriptega tablet?
Contact your doctor instantly if you experience any side effects while taking Acriptega tablet. Your physician may also recommend over-the-counter or prescription medications to help manage your side effects.
Q 6. Is Acriptega a PEP drug?
Yes, Acriptega tablet is a medication that is used as part of Pre-Exposure Prophylaxis (PEP) to help prevent HIV infection in individuals who are at high risk of contracting the virus.
Q 7. what is Acriptega used for?
Acriptega treats HIV in adults and children (≥40kg) by inhibiting enzymes necessary for virus replication. While it reduces transmission risk, HIV-related infections and transmission remain possible during its use.
Q 8. How to take Acriptega?
It is taken orally. Your doctor will decide the dose and duration of Acriptega based on the disease condition and other factors. Always take this medicine as prescribed by your doctor. Take the tablet at the same time. Do not take an additional dose to compensate for the missed dose. Do not chew, dissolve, crush, or break the tablet.
Fact Box of Acriptega Tablet
Molecule name: Dolutegravir + Lamivudine + Tenofovir disoproxil fumarate | Therapeutic class: Antiretrovirals |
Pharmacological class: 1. Integrase strand transfer inhibitor (INSTI) 2. Nucleoside reverse transcriptase inhibitors (NRTIs) | Indications: HIV-1 Infection
|
References
- Aurobindo Pharma, US Food and Drug Administration, [Revised on Apr 2018] [Accessed on 22nd May 2023] https://www.accessdata.fda.gov/drugsatfda_docs/pepfar/209618PI.pdf
- KD Tripathi, Antiviral Drugs (Anti-retrovirus), Essentials of Medical Pharmacology, 8th Edition, 2019, 860-872.
- https://hivinfo.nih.gov/understanding-hiv/fact-sheets/fda-approved-hiv-medicines
- https://www.hiv.gov/hiv-basics/hiv-prevention/using-hiv-medication-to-reduce-risk/pre-exposure-prophylaxis
Disclaimer
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