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Adthal 50mg Capsule
Prescription Required
Salt Composition : Thalidomide
Manufacturer : ADLEY FORMULATIONS
Origin of Medicine : India
10 Capsule(s) In A Strip
Introduction to Adthal 50mg Capsule
Adthal 50mg Capsule belongs to the class of medication called immunomodulatory agents. It consists of the active ingredient Thalidomi. It is primarily indicated to treat patients recently diagnosed with multiple myeloma. Multiple myeloma is a type of cancer mainly affecting certain white blood cells called the plasma cell. These cells grow uncontrolled and accumulate in the bone marrow, damaging the bones and kidneys. It is also prescribed for treating moderate to severe new lesions in leprosy. Leprosy is a chronic disease that affects the skin and nerves and is caused by a bacteria called Mycobacterium leprae.
The common side effects that are likely to be associated with Adthal 50mg Capsule are Sleepiness, headache, dizziness, rashes, pain, tiredness, constipation, nausea, impotence, loss of appetite, fever, depression, etc. Inform your doctor if any of these side effects disturb or persist in you. Consult your physician and use an effective contraceptive to avoid unwanted pregnancy during this treatment.
Inform your medical professional if you are allergic to Adthal 50mg Capsule and its ingredients. Inform your doctor if you have blood clots, heart attack, neuropathy (pain in the hands or feet caused by nerve damage), slow heart rate, low and high blood pressure, liver or kidney problems, viral infections like HIV, hepatitis B virus, and varicella zoster. Your physician will monitor the thyroid function before and during treatment with this medication. Stop taking Adthal 50mg Capsule and consult a doctor immediately if you think you are pregnant, if you have irregular periods, missed a period, have any change in menstrual bleeding, or if you had sex without using effective birth control. It is not recommended for adolescents and children under 18 years of age.
Uses of Adthal 50mg Capsule
- Adjunct to Dexamethasone for treating newly diagnosed multiple myeloma.
- Treatment of moderate to severe leprosy.
- Prevention of recurrence of skin lesions in leprosy.
Therapeutic Effects of Adthal 50mg Capsule
Adthal 50mg Capsule reduces inflammation and regulates the immune system. It works by enabling the body’s immune system and attacking the cancer cells. It inhibits tumor necrosis factor-alpha, increases the production of interleukin-10 and interacts with the T-cells to generate an immune response. It halts the growth of blood vessels in cancer cells and arrests their development.
Interaction of Adthal 50mg Capsule with other drugs
Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional or vitamin supplements, and herbal products you take or have taken before the treatment. Certain medications may interact with Adthal 50mg Capsule and can cause undesirable side effects.
More Information about Adthal 50mg Capsule
- Do not store above 30°C
- Keep out of sight and reach of pets and children.
- Do not freeze the medicine.
- Always check the expiry date before consuming it.
How to consume Adthal 50mg Capsule
Take the Adthal 50mg Capsule as your physician advises. Take medicine at a fixed time. Do not crush, chew, or open the medicine. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition.
Safety Advices for Adthal 50mg Capsule
Pregnancy
Adthal 50mg Capsule causes birth defects and the death of the fetus and it is unsafe to consume during pregnancy. Inform your physician before taking this medicine if you are pregnant or think you might be pregnant.
Breast Feeding
Adthal 50mg Capsule is unsafe to consume because it passes through breast milk. Consult your physician for advice before breastfeeding.
Lungs
It is unknown whether Adthal 50mg Capsule is safe for patients with lung problems. Inform your physician if you have any lung disease before starting the treatment. Contact your doctor if you experience any lung-related symptoms.
Liver
It is unknown whether Adthal 50mg Capsule is safe for patients with liver problems. Inform your physician if you have any liver disease before starting the treatment. Contact your doctor if you experience any liver-related symptoms.
Alcohol
It is not recommended to consume alcohol while taking Adthal 50mg Capsule. Consult your doctor for more information.
Driving
Avoid driving or doing things that require concentration if you experience any side effects. Contact your doctor for more information.
Side Effects of Adthal 50mg Capsule
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Serious
- Nerve damage
- Decreased blood pressure
- Low WBC count
- Slow heartbeat
- Serious allergic reactions
- Tumor lysis syndrome
- Sudden pain in the chest or difficulty breathing
- Pain and swelling of legs
- Bleeding or bruising without injury
Common
- Sleepiness
- Rashes
- Headache
- Dizziness
- Impotence
- Decreased energy or strength
- Pain
- Tiredness
- Low calcium and blood count levels
- Swelling of hands and feet
- Constipation
- Numbness or tingling
- Nausea and reduced appetite
- Anxiety, depression, confusion and mood swings
- Fever
- Weight loss or weight gain
- Indigestion, vomiting and dry mouth
- Muscle cramps
- Blurred vision
- Chest infection, lung disease
- Ear problems
- Kidney damage
Word of Advice
Talk to your physician if you have had a heart attack, blood disorders, high BP or high cholesterol. Inform your physician before starting treatment, seizures, skin reactions or severe infections. Inform your physician if you smoke or drink alcohol. Before starting the treatment, inform your doctor about all the underlying medical conditions. Do not stop the medicine until your doctor advises. Do not double-dose the medicine to make up for a forgotten dose. Notify your doctor if you experience any serious side effects. Contact your doctor for more information.
FAQs
Q 1. Can children use Adthal 50mg Capsule?
No, Adthal 50mg Capsule is not recommended for usage in children and young people under 18.
Q 2. What is the best time to take a Adthal 50mg Capsule?
It is best to take a Adthal 50mg Capsule once a day at bedtime. This will make you less likely to feel sleepy at other times.
Q 3. What happens if I miss my Adthal 50mg Capsule dose?
Take the recommended dose if you miss a Adthal 50mg Capsule dose by less than 12 hours. If you miss this dose by more than 12 hours, skip the missing dose and start your next dose at the regular time.
Q 4. What are the side effects of Adthal 50mg Capsule?
The most common side effects of Adthal 50mg Capsule are sleepiness, rashes, headache, dizziness, impotence, decreased energy, pain, tiredness, low calcium and blood count levels, swelling of hands and feet, constipation, numbness or tingling, nausea, reduced appetite, anxiety, depression, confusion, mood swings, fever, weight changes, indigestion, vomiting, dry mouth, muscle cramps, blurred vision, chest infection, lung disease, ear problems, and kidney damage.
Q 5. Is it safe to become a father to a child while taking Adthal 50mg Capsule?
It is not safe to become a father while taking Adthal 50mg Capsule because this medication passes into the semen, which leads to severe birth defects in the unborn baby.
Q 6. Can I donate my blood while taking Adthal 50mg Capsule?
No, You should not donate blood while taking Adthal 50mg Capsule during treatment and four weeks after discontinuation of this medication. Because the donated blood might be given to pregnant women as it causes birth defects in the unborn baby.
Fact Box of Adthal 50mg Capsule
| Molecule Name: Thalidomide | Therapeutic class: Immunomodulatory agents
|
Pharmacological class: Anti-infectives
| Indications: 1. Adjunct to Dexamethasone for treating newly diagnosed multiple myeloma. 2. Treatment of moderate to severe leprosy. 3. Prevention of recurrence of skin lesions in leprosy |
References
1. Celgene Europe B.V, Electronic Medicines Compendium (EMC), [Revised on Aug 2021] [Accessed on 19th August 2023], https://www.medicines.org.uk/emc/files/pil.6317.pdf
2. Celgene Corporation, US Food and Drug Administration, [Revised on Jun 2019] [Accessed on 19th August 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/020785s067lbl.pdf
3. Douglas F. Lake and Adrienne D. Briggs, Immunopharmacology, Lange’s Basic & Clinical Pharmacology, 14th Edition, 2018, 977-1002.
4. D.H. Dockrell, S. Sundar, B.J. Angus, R.P. Hobson, Infectious Disease, Davidson’s Principles and Practice of Medicine, 22nd Edition, 2014, 293-386.
Disclaimer
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