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Boostrix Injection
Prescription Required
Salt Composition : Diptheria Pertussis Tetanus (dpt) Vaccine
Manufacturer : GLAXO SMITHKLINE PHARMACEUTICALS LTD
Origin of Medicine : India
1 Prefilled Syringe(s)
Introduction to Boostrix Injection
Boostrix Injections are the bacterial vaccine belonging to the class of combination vaccines containing the active ingredient Diphtheria Pertussis Tetanus (DPT) Vaccine. It is a vaccine used for protecting children against respiratory, skin disease, whooping cough, polio, hepatitis B, and influenza. Diphtheria is a contagious bacterial infection that primarily affects the respiratory system and results in complications, including heart and nervous system damage. Pertussis is characterized by severe coughing fits and a "whooping" sound during inhalation. It can be particularly dangerous for infants, causing serious complications such as pneumonia and seizures. Tetanus, also known as "lockjaw," is caused by a toxin produced by the bacterium. It mainly affects the nervous system and leads to severe muscle stiffness and spasms.
Before vaccinating, inform your doctor if you or your child has any problems with the blood that causes easy bruising, prolonged bleeding after minor cuts (e.g., hemophilia or thrombocytopenia) or if you are on blood-thinning medications. They will evaluate and determine the appropriate course of action regarding vaccination. If your child has taken a booster dose of diphtheria and tetanus vaccine within the last four weeks, the administration of this vaccine should be deferred. Your doctor will refer to official recommendations to determine the appropriate timing for the next vaccination. Suppose you or your child has a weakened or compromised immune system due to conditions like HIV infection, cancer, or immunosuppressive medications. In that case, the immune response to the Boostrix injection may be reduced. In such cases, your doctor will assess the risks and benefits of vaccination and may recommend alternative strategies or timing.
Do not use this vaccine if your child has an acute severe febrile illness because the immune system may already be compromised due to the illness, and receiving a vaccine during this time may not provide an optimal immune response. So, the vaccination should be delayed until you or your child has recovered completely. Suppose you or your child has experienced Guillain-Barré syndrome(a neurological disorder in which the body's immune system mistakenly attacks the peripheral nerves) within six weeks of a previous dose of a tetanus-containing vaccine. In that case, your doctor will evaluate the situation and decide whether this vaccine should be given. This vaccine during pregnancy allows protection to be passed on to the child in the womb to protect from whooping cough during the first few months of life. Booster doses are recommended in later childhood and adulthood to maintain protection. The Boostrix injection is administered in a series of doses during infancy and childhood to provide long-lasting immunity against the disease.
Uses of Boostrix Injection
- Prevention from three infectious diseases (diphtheria, pertussis, and tetanus).
Therapeutic Effects of Boostrix Injection
The Boostrix injection stimulates the body's immune system to produce antibodies against diphtheria, pertussis, and tetanus bacteria. These antibodies help to protect against future infection by these bacteria.
Interaction of Boostrix Injection with other drugs
Inform your doctor about all your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Boostrix Injection, reducing effectiveness by causing undesirable side effects.
More Information about Boostrix Injection
- Store the Boostrix Injection in a refrigerator between (2°C-8°C).
- Keep away from moisture, heat, and light.
- It should not be frozen.
How to consume Boostrix Injection
The Boostrix Injection is administered as an injection into the upper arm. The specific dosage and number of injections required can vary on the patient's age and vaccination history. For infants, the vaccine is typically given in three doses, with the first dose administered at birth or shortly after that and the second and third doses given at 1-2 months and six months of age.
Safety Advices for Boostrix Injection
Pregnancy
Consult your doctor if you are pregnant or think you might be pregnant or are planning to have a baby. Your doctor will help you decide if you should receive Boostrix Injection during pregnancy.
Breast Feeding
Consult your doctor if you are breastfeeding. Your doctor will help you decide if you should receive Boostrix Injection during breastfeeding.
Lungs
Patients with pre-existing lung disease should consult a healthcare provider before administering the Boostrix Injection.
Liver
Consult your doctor if you have any liver disease before administering the Boostrix Injection.
Alcohol
The Boostrix Injection is safe for individuals who consume alcohol. There is no data to suggest that alcohol consumption affects the safety or effectiveness of the vaccine.
Driving
The Boostrix Injection is not known to affect driving ability. It is an injected vaccine that does not contain substances known to cause drowsiness or impair motor skills.
Side Effects of Boostrix Injection
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Serious
- Lack of awareness or consciousness
- Fits
- Rashes
- Blisters
- Breathlessness
- Difficulty swallowing
- The sudden drop in blood pressure
Common
- Diarrhoea
- Vomiting
- High temperature
- Swelling and redness at the injection site
- Headache
- Nausea
- Aching or swollen joints
Word of Advice
Your doctor or nurse will not give you the vaccine into a blood vessel, into the buttocks, or under the skin. In case of blood clotting disorders, they may decide to inject under the skin, although this might result in more local side effects, including a small lump under the skin. If you have further doubts regarding the Boostrix Injection, ask your doctor, pharmacist, or nurse for clarification.
FAQs
Q 1. What does the Boostrix injection protect against?
The Boostrix injection protects against three diseases: diphtheria, pertussis (whooping cough), and tetanus.
Q 2. Who should receive the Boostrix injection?
The Boostrix injection is given to infants and young children as part of routine childhood immunization schedules. Booster doses are also recommended during adolescence and adulthood to maintain protection.
Q 3. What kind of vaccine is the Boostrix Injection?
The Boostrix Injection is a combination vaccine.
Q 4. Are there any side effects of the Boostrix injection?
Common side effects of the Boostrix injection may include rash, redness, pain or swelling at the injection site, mild fever, and fussiness. Serious side effects are mostly rare, but they can include allergic reactions. It's important to report any unusual or severe reactions to your doctor immediately.
Q 5. How is the Boostrix Injection administered?
Boostrix Injection can be administered into the upper arm for adults and older children. It can be administered in the thigh muscle of toddlers for younger children.
Q 6. Are three doses of the Boostrix Injection recommended?
Yes. Three doses of the Boostrix Injection are recommended. The first dose is given at around two months of age, followed by the second and third doses administered at approximately 4 to 6 weeks intervals. This initial schedule helps to gain a strong immune response in infants and children. Following the initial schedule, booster doses are recommended to maintain immunity throughout childhood and into adulthood. These booster doses help to give sustained protection against diphtheria, pertussis, and tetanus.
Q 7. How does the Boostrix injection work?
The Boostrix injection stimulates the body's immune system to produce antibodies against diphtheria, pertussis, and tetanus bacteria. These antibodies help to protect against future infection by these bacteria.
Q 8. Is the Boostrix injection mandatory?
The Boostrix injection is mandatory in many countries for routine immunization programs. However, requirements may vary by region or country. It's necessary to consult with your doctor or local health authority for information on vaccine requirements in your area.
Q 9. How long does the protection from the Boostrix injection last?
The protection from the Boostrix injection can last for several years, but booster doses are recommended to maintain immunity.
Fact Box of Boostrix Injection
Molecule name: Diphtheria Pertussis Tetanus (DPT) Vaccine | Therapeutic class: Bacterial vaccines |
Pharmacological class: Combination Vaccine | Indications: Prevention from three infectious diseases (diphtheria, pertussis, and tetanus). |
References
- Package leaflet: Information for the user REPEVAX- medicines. Available at: https://www.medicines.org.uk/emc/files/pil.5580.pdf (Accessed: 15 May 2023).
- Diphtheria Pertussis Tetanus (DPT) Vaccine, Package leaflet. Information for the user. Available at: https://www.fda.gov/media/74035/download (Accessed: 15 May 2023).
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